Results 241 to 250 of about 448,727 (340)

siRNA Delivery via Cross‐Linked Gelatin Microparticles Enables Targeted Modulation of Osteogenic‐Vascular Cross‐Talk: An Advanced Human 3D in Vitro Test System for Therapeutic siRNA

Advanced Healthcare Materials, EarlyView.
Osteogenic‐angiogenic cross‐talk is a vital prerequisite for vascularized bone regeneration. In this study, we investigated the effects of siRNA‐mediated silencing of two inhibitory proteins, Chordin and WWP‐1, via CaP‐NP‐loaded gelatin microparticles in osteogenically differentiated microtissues.
Franziska Mitrach, Jonas Kubat, Stefan Simm, Alexandra H. Springwald, Burak Demir, Anton Liebezeit, Michael C. Hacker, Michaela Schulz‐Siegmund   +7 more
wiley   +1 more source

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

Advanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang, Si‐Bo Yang, Yan Luo, Xiao‐Di Sun, Bo‐Hao Chang, Da‐Qiang Zhou, Jun‐Jie Jiang, Ya‐Nan Li, Jie‐Hong Wu, Hui‐Juan Jin, Hang Yang, Hang Hu, Yi‐Fan Zhou, Bo Hu   +13 more
wiley   +1 more source

Sox5 controls the establishment of quiescence in neural stem cells during postnatal development. [PDF]

PLoS Biol
Medina-Menéndez C, Tirado-Melendro P, Li L, Rodríguez-Martín P, Melgarejo-de la Peña E, Díaz-García M, Valdés-Bescós M, López-Sansegundo R, Morales AV.   +8 more
europepmc   +1 more source

Microprinted Stem Cell Niches Reveal Compounding Effect of Colony Size on Stromal Cells‐Mediated Neural Differentiation

, 2017
Ramila Joshi, Pradip Shahi Thakuri, James C. Buchanan, Jun Li, Hossein Tavana   +4 more
openalex   +2 more sources

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

Advanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre, Margherita Bernardeschi, Matteo Battaglini, Gianni Ciofani   +3 more
wiley   +1 more source

The effects of cannabidiol and its main metabolites on human neural stem cells. [PDF]

Exp Biol Med (Maywood)
Latham LE, Gu Q, Liu S, Wang C, Liu F.
europepmc   +1 more source

Mitochondrial Transplantation via Magnetically Responsive Artificial Cells Promotes Intracerebral Hemorrhage Recovery by Supporting Microglia Immunological Homeostasis

Advanced Materials, Volume 37, Issue 13, April 2, 2025.
A type of magnetically responsive artificial cells (ACs) has been developed, demonstrating the loading of mitochondria and self‐enclosure processes to ensure the protection of mitochondrial transport via the bloodstream. The treatment with ACs effectively transplanted mitochondria around the lesion, thereby improving neurological recovery by supporting
Mi Zhou, Jinhui Zang, Yuxuan Qian, Qiang Zhang, Yifan Wang, Tingting Yao, Hongyu Yan, Kai Zhang, Xiaojun Cai, Lixian Jiang, Yuanyi Zheng   +10 more
wiley   +1 more source

Correction to: Remyelination of chronic demyelinated lesions with directly induced neural stem cells. [PDF]

Brain
europepmc   +1 more source

The Critical Balance Between Quiescence and Reactivation of Neural Stem Cells. [PDF]

Biomolecules
Elkin AM, Robbins S, Barros CS, Bossing T.   +3 more
europepmc   +1 more source

Effect of spinal cord extracts after spinal cord injury on proliferation of rat embryonic neural stem cells and Notch signal pathway in vitro

, 2014
Qingzhong Zhou, Ge Zhang, Haibo Long, Fei Lei, Fei Ye, Xufeng Jia, Yunlong Zhou, Jianping Kang, Daxiong Feng   +8 more
openalex   +1 more source