Results 191 to 200 of about 4,989,359 (237)
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A new approach to the synthesis of neuraminic acid analogues
Tetrahedron Letters, 1991Abstract 2-Alkoxy acrylate derivatives 8 and 11 , readily prepared from D-glucono-1,5-lactone by ring opening and β-elimination, are converted into neuraminic acid analogues 9 and 12 via debenzylation and spontaneous cyclization or ring closure via oxymercuration-demercuration, respectively.
Petinka I. Vlahova +2 more
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The serum neuraminic acid distribution. I. Methodology.
The Journal of laboratory and clinical medicine, 1957Abstract 1.1. The quantitative distribution of serum neuraminic acid between the albumin and globulin protein fractions, as separated by salt fractionation, was investigated for 37 normal subjects (26 adults and 11 children) and for 111 patients with neurologic and nonneurologic diseases using a modified diphenylamine colorimetric reaction.
Abraham Saifer, Shirley Gerstenfeld
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Arg314 is essential for catalysis by N-acetyl neuraminic acid synthase from Neisseria meningitidis.
Biochemistry, 2013The sialic acid N-acetylneuraminic acid (NANA) has a key role in the pathogenesis of a select number of neuroinvasive bacteria such as Neisseria meningitidis.
Dmitri D. A. Joseph +2 more
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Neuraminic acid-specific modification and tritium labelling of gangliosides
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 19771. A crude ganglioside mixture and pure GM1 and GD1a from bovine brain grey matter were prepared on a large scale. 2. The C7- and G8-analogues of NeuNAc were prepared from Collocalia mucoid and their structures established by gas-liquid chromatography and mass spectrometry. 3.
Anthony P. Corfield +3 more
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�ber den Neuramins�uregehalt in kindlichen Blutseren
Klinische Wochenschrift, 1959Die an die Blutserumeiweiskorper gebundene Neuraminsaure wurde bei 60 Kindern sowie bei 12 Muttern und ihren neugeborenen Kinden nach der vonBohm u. Mitarb. angegebenen Methodik bestimmt. Es konnte dabei nachgewiesen werden, das bei Fruhgeborenen, reifen Neugeborenen und jungen Sauglingen der Serum-Neuraminsaurespiegel niedriger liegt als bei ...
Wolfgang Pullig, Hanns Löhr
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Applied Microbiology and Biotechnology, 1995
In an optimized sorbitol/yeast extract/mineral salt medium up to 12 U/l CMP-N-acetyl-neuraminic-acid (Neu5Ac) synthetase was produced by Escherichia coli K-235 in shake-flask culture. A colony mutant of this strain, E. coli K-235/CS1, was isolated with improved enzyme formation: in shake flasks with a yield of up to 20.8 U/l and 54 mU/mg protein in the
Matthias Kittelmann +4 more
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In an optimized sorbitol/yeast extract/mineral salt medium up to 12 U/l CMP-N-acetyl-neuraminic-acid (Neu5Ac) synthetase was produced by Escherichia coli K-235 in shake-flask culture. A colony mutant of this strain, E. coli K-235/CS1, was isolated with improved enzyme formation: in shake flasks with a yield of up to 20.8 U/l and 54 mU/mg protein in the
Matthias Kittelmann +4 more
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Neuraminic acid — Structure, Chemistry, Biological Activity
2002Abstract The interest in the sialic acids chemistry has rapidly increased in last years, especially since their involvement in the regulation of a great variety of biological phenomena was recognised. In this paper we are interested in the biological function of sialic acid that it is able to interact with biomolecules, as well as viruses are.
Armandodoriano Bianco +1 more
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Alterations of acyl-neuraminic acids on T-lymphocytes in cases of melanoma
Klinische Wochenschrift, 1988Content and distribution of the different sialic acids on human lymphocytes, isolated from 7-10 ml of fresh human blood, were determined using microanalytical methods, such as HPLC and a colorimetric test. Comparison of the data of patients with melanoma with those of healthy persons shows an evident increase of the sialic acid content combined with a ...
W Klose +5 more
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Some Observations on Certain Mucoproteins containing Neuraminic Acid
Nature, 1959IT is now well established1–4 that mucoproteins, particularly those containing neuraminic acids, play a major part in the natural defences of the human body. With the object of determining what part is played by such mucoproteins in human cancer we have assessed the amount and distribution of mucoproteins containing neuraminic acid by determination of ...
S. A. BARKER +3 more
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, 2014
Quinoxaline derivatization has been the most commonly used approach for sialic acid quantitation of biological samples and glycoproteins by either HPLC or LC-MS/MS.
Libo Wang +4 more
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Quinoxaline derivatization has been the most commonly used approach for sialic acid quantitation of biological samples and glycoproteins by either HPLC or LC-MS/MS.
Libo Wang +4 more
semanticscholar +1 more source