Results 171 to 180 of about 134,617 (294)

Pulsed Electromagnetic Fields: A Novel Attractive Therapeutic Opportunity for Neuroprotection After Acute Cerebral Ischemia

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives Acute cerebral ischemia is characterized by several pathological processes evolving during time, which contribute to the final tissue damage. Secondary processes, such as prolonged inflammatory response, impaired mitochondrial function and oxidative stress, are responsible for the progression of brain injury to the peri‐infarct area,
Fioravante Capone, Simona Salati, Fabrizio Vincenzi, Micaela Liberti, Giorgio Aicardi, Francesca Apollonio, Katia Varani, Ruggero Cadossi, Vincenzo Di Lazzaro   +8 more
wiley   +1 more source

Prenatal valproate exposure alters midbrain and striatal neuronal morphology along with dopamine levels. [PDF]

Brain Struct Funct
Bugar Bodorova B, Havranek T, Mihalj D, Kupkova K, Bogyova E, Falougy HE, Bacova Z, Bakos J.   +7 more
europepmc   +1 more source

Somatic cell reprogramming for Parkinson's disease treatment

Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

Structural alteration of neurons in schizophrenia and its relation with auditory hallucination. [PDF]

Eur Psychiatry
Mizutani R, Saiga R, Yamamoto Y, Inomoto C, Kajiwara H, Kakimoto Y, Yasutake M, Uesugi M, Takeuchi A, Uesugi K, Terada Y, Suzuki Y, Nikitin V, De Carlo F, Torii Y, Kushima I, Ozaki N, Iritani S, Arai M, Oshima KI, Itokawa M.   +20 more
europepmc   +1 more source

Cordycepin mediates neuroprotection against apoptosis via ERK/CREB signaling activation in Aβ1–42‐induced neuronal cell models

Ibrain, Volume 11, Issue 1, Page 84-97, Spring 2025.
This study demonstrates cordycepin's neuroprotective effects against Aβ1–42‐induced apoptosis in neuronal cells, mediated through the activation of the extracellular signal‐regulated kinase/cyclic AMP‐responsive element‐binding protein (ERK/CREB) signaling pathway.
Wenshu Zhou, Cheng Wang, Yige Tan, Philip Lazarovici, Xiaoyan Wen, Shaoping Li, Wenhua Zheng   +6 more
wiley   +1 more source

APOE3 astrocytes can rescue lipid abnormalities and dystrophic neurites of APOE4 human neurons. [PDF]

PNAS Nexus
Halim DO, Di Biase E, Rajon A, Jordi L, Hallett PJ, Isacson O.   +5 more
europepmc   +1 more source

Multimodal MRI and multiomics reveal high‐risk neurophenotype in brain‐gut circuits as therapeutic target for Crohn's disease

Interdisciplinary Medicine, EarlyView.
Through a translational framework combining prospective dual‐center clinical cohorts with dextran sulfate sodium‐induced colitis models, this work integrated advanced neuroimaging, multi‐omics and neuromodulation interventions to redefine the high‐risk neurophenotype as a sustained pathogenic driver rather than a mere phenomenon, proposing brain‐gut ...
Xuehua Li, Ruonan Zhang, Xiaodi Shen, Shaochun Lin, Chuhuai Wang, Weikai Zheng, Weimiao Kong, Zihao Lin, Rongchang Li, Caiguang Liu, Xin Cao, Li Huang, Weitao He, Jinjiang Lin, Haijie Wang, Zhoulei Li, Marietta Iacucci, Subrata Ghosh, Zhenpeng Peng, Canhui Sun, Minhu Chen, Guang Yang, Yejun Wang, Ren Mao, Shi‐Ting Feng   +24 more
wiley   +1 more source

Paternal Exposure to the Neonicotinoid Pesticide Clothianidin Alters Sperm MicroRNA Profiles in Mice and Intergenerationally Reduces Locomotor Activity in Male Offspring

Journal of Applied Toxicology, EarlyView.
ABSTRACT Accumulating evidence suggests that paternal environmental factors have epigenetic effects on sperm and influence offspring. Neonicotinoid pesticides (NNs), which are widely used around the world, are known to affect offspring phenotypes through maternal exposure in mice, but the effect of the paternal exposure remains unknown.
Makiko Ito, Tetsushi Hirano, Sarika Nunobiki, Ayano Yoshimoto, Yukako Hara, Yuya Ishida, Sakura Yonoichi, Youhei Mantani, Toshifumi Yokoyama, Yoshiaki Tabuchi, Yoshinori Ikenaka, Nobuhiko Hoshi   +11 more
wiley   +1 more source

AAV-Driven miR-146a Promotes Neurite Outgrowth and Axonal Regeneration in Cortical Neurons. [PDF]

J Neurochem
Matos VUS, Almeida RA, Ferreira CG, Alves MTR, Braga MP, Silva MC, da Silva TF, Guimarães PPG, Soriani FM, Caramelli P, Costa MR, Michel U, Ribas VT.   +12 more
europepmc   +1 more source

Clinical Applications of Electrical Conductivity Imaging Using MRI

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Magnetic resonance imaging (MRI) has emerged as a noninvasive technique for probing the electrical properties of biological tissues: electrical conductivity and relative permittivity. This review focuses on the electrical conductivity and provides a comprehensive overview of applications across both low‐ and high‐frequency regimes.
Stefano Mandija, Khin Khin Tha, Nitish Katoch, Cihan Göksu, Ulrich Katscher, Rosalind Sadleir, Kyu‐Jin Jung, Jierong Luo, Ilias I. Giannakopoulos, Dong‐Hyun Kim, Karin Shmueli, Riccardo Lattanzi, Yusuf Ziya Ider, Axel Thielscher, Cornelis van den Berg   +14 more
wiley   +1 more source