Results 1 to 10 of about 56,568 (206)

Method for AFM investigation of lateral forces required for the surface detachment of neurites [PDF]

open access: yesScientific Reports
Resprouting of neurites to establish direct connections between stimulation electrodes and spiral ganglion neurons is of considerable interest in current cochlear implant research.
Vinzent Braemer, Gerrit Paasche
doaj   +2 more sources

Quantitative reconstruction of neuronal mitochondrial network in neurites and somata in rat hippocampus and prefrontal cortex [PDF]

open access: yesFrontiers in Physiology
IntroductionMitochondrial networks exhibit striking heterogeneity in their morphology and distribution across different neuronal compartments, reflecting the diverse metabolic demands of these structures.MethodsIn this study, we used automated tape ...
Lu Wang   +27 more
doaj   +2 more sources

Infectivity of Human Olfactory Neurons to SARS-CoV-2: A Link to Anosmia

open access: yesOman Medical Journal, 2021
Objectives: We sought to determine whether SARS-CoV-2 infections are associated with anosmia and if this virus infects other neuronal cells. We utilized male and female olfactory neuronal cell lines and other olfactory cell lines to determine the viral ...
Omar Bagasra   +5 more
doaj   +1 more source

Magnetic activation of TREK1 triggers stress signalling and regulates neuronal branching in SH-SY5Y cells

open access: yesFrontiers in Medical Technology, 2022
TWIK-related K+ 1 (TREK1) is a potassium channel expressed in the nervous system with multiple functions including neurotransmission and is a prime pharmacological target for neurological disorders.
Michael Rotherham   +8 more
doaj   +1 more source

Formation of Three-Dimensional Spheres Enhances the Neurogenic Potential of Stem Cells from Apical Papilla

open access: yesBioengineering, 2022
Cell-based neural regeneration is challenging due to the difficulty in obtaining sufficient neural stem cells with clinical applicability. Stem cells from apical papilla (SCAPs) originating from embryonic neural crests with high neurogenic potential ...
Mohammed S. Basabrain   +8 more
doaj   +1 more source

Probing brain tissue microstructure with MRI: principles, challenges, and the role of multidimensional diffusion-relaxation encoding

open access: yesNeuroImage, 2023
Diffusion MRI uses the random displacement of water molecules to sensitize the signal to brain microstructure and to properties such as the density and shape of cells. Microstructure modeling techniques aim to estimate these properties from acquired data
Björn Lampinen   +9 more
doaj   +1 more source

A peptide inhibitor that rescues polyglutamine-induced synaptic defects and cell death through suppressing RNA and protein toxicities

open access: yesMolecular Therapy: Nucleic Acids, 2022
Polyglutamine (polyQ) diseases, including spinocerebellar ataxias and Huntington’s disease, are progressive neurodegenerative disorders caused by CAG triplet-repeat expansion in the coding regions of disease-associated genes. In this study, we found that
Shaohong Isaac Peng   +5 more
doaj   +1 more source

Sphingomyelin in Human Breast Milk might be Essential for the Hippocampus Maturation

open access: yesFrontiers in Bioscience-Landmark, 2022
Background: It has been established that sphingomyelin present human breast milk is useful for the brain maturation and cognitive development. At 10 days of breastfeeding the sphingomyelin content is double that present in cow’s milk and its content is ...
Elisabetta Albi   +15 more
doaj   +1 more source

Are there roles for heterogeneous ribosomes during sleep in the rodent brain?

open access: yesFrontiers in Molecular Biosciences, 2022
The regulation of mRNA translation plays an essential role in neurons, contributing to important brain functions, such as brain plasticity and memory formation. Translation is conducted by ribosomes, which at their core consist of ribosomal proteins (RPs)
Isla M. Buchanan   +4 more
doaj   +1 more source

RNA Localization and Local Translation in Glia in Neurological and Neurodegenerative Diseases: Lessons from Neurons

open access: yesCells, 2021
Cell polarity is crucial for almost every cell in our body to establish distinct structural and functional domains. Polarized cells have an asymmetrical morphology and therefore their proteins need to be asymmetrically distributed to support their ...
Maite Blanco-Urrejola   +6 more
doaj   +1 more source

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