Results 21 to 30 of about 56,568 (206)

Morphological identification and development of neurite in Drosophila ventral nerve cord neuropil. [PDF]

open access: yesPLoS ONE, 2014
In Drosophila, ventral nerve cord (VNC) occupies most of the larval central nervous system (CNS). However, there is little literature elaborating upon the specific types and growth of neurites as defined by their structural appearance in Drosophila ...
Guangming Gan, Huihui Lv, Wei Xie
doaj   +1 more source

The Combinatorics of Neurite Self-Avoidance [PDF]

open access: yesNeural Computation, 2011
During neural development in Drosophila, the ability of neurite branches to recognize whether they are from the same or different neurons depends crucially on the molecule Dscam1. In particular, this recognition depends on the stochastic acquisition of a unique combination of Dscam1 isoforms out of a large set of possible isoforms.
Elizabeth M. Forbes   +2 more
openaire   +5 more sources

Neurite Outgrowth: A Flick of the Wrist [PDF]

open access: yesCurrent Biology, 2007
A new study has shown that, near the tip of a growing axon, dephosphorylation of the microtubule-associated protein Doublecortin is controlled by protein phosphatase 1 and its regulator spinophilin. This results in spatially regulated microtubule bundling within the axon and more efficient axon outgrowth.
Dehmelt, L., Halpain, S.
openaire   +3 more sources

A Method to Culture GABAergic Interneurons Derived from the Medial Ganglionic Eminence

open access: yesFrontiers in Cellular Neuroscience, 2018
Understanding the mechanisms guiding interneuron development is a central aspect of the current research on cortical/hippocampal interneurons, which is highly relevant to brain function and pathology.
Sira A. Franchi   +8 more
doaj   +1 more source

The role of TLR4 in the paclitaxel effects on neuronal growth in vitro. [PDF]

open access: yesPLoS ONE, 2013
Paclitaxel (Pac) is an antitumor agent that is widely used for treatment of solid cancers. While being effective as a chemotherapeutic agent, Pac in high doses is neurotoxic, specifically targeting sensory innervations.
Elena E Ustinova   +3 more
doaj   +1 more source

Construction of an image recognition algorithm based on neurite outgrowth of human motor neurons and its application in toxicological evaluation

open access: yes陆军军医大学学报, 2023
Objective To develop an MATLAB algorithm for the automated measurement of motor neuron (MN) neurites and apply this algorithm to evaluate the organophosphate flame retardant tris (2-chloroethyl) phosphate (TCEP) on the growth of MN neurites.
DAI Zhiyuan   +5 more
doaj   +1 more source

The interplay between branching and pruning on neuronal target search during developmental growth: functional role and implications. [PDF]

open access: yesPLoS ONE, 2011
Regenerative strategies that facilitate the regrowth and reconnection of neurons are some of the most promising methods in spinal cord injury research. An essential part of these strategies is an increased understanding of the mechanisms by which growing
Remus Oşan, Emily Su, Troy Shinbrot
doaj   +1 more source

The cytoskeleton and neurite initiation [PDF]

open access: yesBioArchitecture, 2013
Neurons begin their life as simple spheres, but can ultimately assume an elaborate morphology with numerous, highly arborized dendrites, and long axons. This is achieved via an astounding developmental progression which is dependent upon regulated assembly and dynamics of the cellular cytoskeleton.
openaire   +3 more sources

Cryopreservation of Primary Mouse Neurons: The Benefit of Neurostore Cryoprotective Medium

open access: yesFrontiers in Cellular Neuroscience, 2018
Primary neuronal culture from rodents is a well-established model to investigate cellular neurobiology in vitro. However, for this purpose cell cultures need to be generated expressly, requiring extensive animal handling.
Francesca Pischedda   +7 more
doaj   +1 more source

Competitive dynamics during resource-driven neurite outgrowth. [PDF]

open access: yesPLoS ONE, 2014
Neurons form networks by growing out neurites that synaptically connect to other neurons. During this process, neurites develop complex branched trees. Interestingly, the outgrowth of neurite branches is often accompanied by the simultaneous withdrawal ...
J J Johannes Hjorth   +3 more
doaj   +1 more source

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