Results 11 to 20 of about 56,568 (206)
Local NGF and GDNF levels modulate morphology and function of porcine DRG neurites, In Vitro. [PDF]
PLoS ONE, 2018 Nerve terminals of primary sensory neurons are influenced by their environment through target derived trophic factors, like nerve growth factor (NGF) or glial cell line-derived neurotrophic factor (GDNF).
Andreas Klusch +5 more
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Mechanical stress activates neurites and somata of myenteric neurons [PDF]
Frontiers in Cellular Neuroscience, 2015 The particular location of myenteric neurons, sandwiched between the 2 muscle layers of the gut, implies that their somata and neurites undergo mechanical stress during gastrointestinal motility.
Eva Maria Kugler +6 more
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Patterns, 2021 Summary: One of the most challenging frontiers in biological systems understanding is fluorescent label-free imaging. We present here the NeuriTES platform that revisits the standard paradigms of video analysis to detect unlabeled objects and adapt to ...
Arianna Mencattini +12 more
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Uncovering kinesin dynamics in neurites with MINFLUX
Communications BiologyNeurons grow neurites of several tens of micrometers in length, necessitating active transport from the cell body by motor proteins. By tracking fluorophores as minimally invasive labels, MINFLUX is able to quantify the motion of those proteins with ...
Jan Otto Wirth +5 more
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Mechanisms of neurite repair [PDF]
Current Opinion in Neurobiology, 2020 Upon receiving injury signals, neurons can activate various pathways to reduce harm, initiate neuroprotection, and repair damaged neurite without cell death. Here, we review recent progresses in the study of neurite repair focusing on neuronal cell-autonomous mechanisms, including new findings on ion channels that serve as key regulators to initiate ...
Liu, Han-Hsuan, Jan, Yuh-Nung
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BIO-PROTOCOL, 2016 Neurite outgrowth in culture provides an easy way to determine the effects of a particular substrate or exogenous factor on neuron behavior. Dissociated neurons can be plated on a variety of substrates and the length of the longest neurite outgrowth can be compared.
Angela Filous, Jerry Silver
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Frontiers in Neuroscience, 2020 Subcellular protein delivery is especially important in signal transduction and cell behavior, and is typically achieved by localization signals within the protein.
María Gamarra +11 more
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Ataxia in Patients With Bi-Allelic NFASC Mutations and Absence of Full-Length NF186
Frontiers in Genetics, 2019 The etiology of hereditary ataxia syndromes is heterogeneous, and the mechanisms underlying these disorders are often unknown. Here, we utilized exome sequencing in two siblings with progressive ataxia and muscular weakness and identified a novel ...
Malin Kvarnung +26 more
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Consequences of Neurite Transection In Vitro [PDF]
Journal of Neurotrauma, 2012 In order to quantify degenerative and regenerative changes and analyze the contribution of multiple factors to the outcome after neurite transection, we cultured adult mouse dorsal root ganglion neurons, and with a precise laser beam, we transected the nerve fibers they extended.
Cengiz, Nurettin +4 more
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Frontiers in Cellular Neuroscience, 2019 Functional recovery is poor after peripheral nerve injury and delayed surgical repair or when nerves must regenerate over long distances to reinnervate distant targets.
Tessa Gordon +2 more
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