Results 201 to 210 of about 134,617 (294)

Effects of Tributyltin Chloride on Human Neuronal Differentiation and Mice Brain Development

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT According to the developmental origins of health and disease hypothesis, perinatal exposure to an environmental toxicant during the development of the nervous system could cause a permanent cellular modification that may promote the appearance of neurodegenerative diseases at an older age.
Ester López‐Gallardo   +10 more
wiley   +1 more source

Neuronal Subtype-Specific Expression of γ-Enolase: Its Role in Neuronal Differentiation. [PDF]

open access: yesNeuromolecular Med
Horvat S   +5 more
europepmc   +1 more source

A thermoplastic microfluidic platform with integrated electrospun scaffolds for assessing brain cell‐specific drug selectivity

open access: yesVIEW, EarlyView.
Schematic representation of the microfluidic platform with its advantages. Abstract A major challenge in pharmacology is the limited selectivity of therapeutic compounds toward specific tissues or cells. Drugs often distribute systemically before reaching the intended site of action, affecting nontarget cells and potentially reducing efficacy or ...
Maria Testa   +8 more
wiley   +1 more source

Critical point drying of brain tissue for X‐ray phase‐contrast imaging

open access: yesJournal of Synchrotron Radiation, EarlyView.
X‐ray phase contrast tomography can efficiently image brain tissue at subcellular resolution. Critical point drying allows a gentle replacement of interstitial material by air, enhancing X‐ray phase contrast of the ultrastructural features.X‐ray phase‐contrast tomography can efficiently image brain tissue at subcellular resolution.
Safe Khan   +15 more
wiley   +1 more source

The oscillatory response of the electroretinogram and neuronal adaptation

open access: yesActa Ophthalmologica, EarlyView.
Abstract After more than 50 years, there still remains a challenge and an interest to know more as well as extend and deepen our understanding of the small rapid wavelets, the oscillatory potentials (OPs), of the electroretinogram (ERG) and the neuronal adaptation of the retina.
Lillemor Wachtmeister, Anders Eklund
wiley   +1 more source

Microtubule dynamics in adult retinal ganglion cells and dorsal root ganglion neurons. [PDF]

open access: yesFront Mol Neurosci
Vecino E   +8 more
europepmc   +1 more source

Tau‐targeting active immunotherapy slows progression and reduces pathology in mouse models of tauopathy

open access: yesBrain Pathology, EarlyView.
The efficacy of the novel anti‐tau active immunotherapy, p5555kb, was tested using two mouse models of tau pathology. p5555kb inoculation increased the survival rate and reduced tau pathology in tau‐overexpressing P301L mice and decreased tau seeding in the brains of C57BL/6 mice injected with human‐purified Alzheimer's disease tau.
Christopher M. Brown   +7 more
wiley   +1 more source

CDK2 inhibition promotes neuronal differentiation in neuroblastoma. [PDF]

open access: yesSci Rep
Alzrigat M   +9 more
europepmc   +1 more source

Frontotemporal dementia: Clinical aspects, genetics, and neuropathology of a family with a C9ORF72 expansion in Argentina

open access: yesBrain Pathology, EarlyView.
Immunohistochemistry for TDP‐43: (A)—Dentate gyrus; (B)—Temporal lobe. Abstract Frontotemporal dementia (FTD) is the second most common cause of early‐onset dementia, typically manifesting before the age of 65, with a mean onset at 58 years. FTD may encompass a spectrum of neurodegenerative disorders resulting from frontotemporal lobar degeneration ...
Karen Daniela Román   +13 more
wiley   +1 more source

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