Results 31 to 40 of about 95,315 (199)

Thrombin enhances NGF-mediated neurite extension via increased and sustained activation of p44/42 MAPK and p38 MAPK. [PDF]

PLoS ONE, 2014
Rapid neurite remodeling is fundamental to nervous system development and plasticity. It involves neurite extension that is regulated by NGF through PI3K/AKT, p44/42 MAPK and p38 MAPK.
Rania E Mufti, Krishna Sarker, Yan Jin, Songbin Fu, Jesusa L Rosales, Ki-Young Lee   +5 more
doaj   +1 more source

Piconewton Mechanical Forces Promote Neurite Growth [PDF]

, 2018
Investigations over half a century have indicated that mechanical forces induce neurite growth, with neurites elongating at a rate of 0.1–0.3 μm h−1 pN−1 when mechanical force exceeds a threshold, with this being identified as 400–1000 pN for neurites of
DE VINCENTIIS, SARA, Falconieri, A., FALCONIERI, ALESSANDRO, Raffa, Vittoria, Raffa, V., Falcone, F., Calatayud, M. Pilar, Goya, Gerardo F., De Vincentiis, S., Calatayud, Maria P., Calatayud, M.P., Cuschieri, Alfred, Cuschieri, A., FALCONE, FRANCESCA, Goya, G.F.   +14 more
core   +1 more source

Transdifferentiation of Human Circulating Monocytes Into Neuronal-Like Cells in 20 Days and Without Reprograming

Frontiers in Molecular Neuroscience, 2018
Despite progress, our understanding of psychiatric and neurological illnesses remains poor, at least in part due to the inability to access neurons directly from patients.
Alfredo Bellon, Alfredo Bellon, Alfredo Bellon, Alfredo Bellon, Alfredo Bellon, Alfredo Bellon, Alfredo Bellon, Amelie Wegener, Amelie Wegener, Amelie Wegener, Amelie Wegener, Adam R. Lescallette, Michael Valente, Michael Valente, Michael Valente, Seung-Kwon Yang, Seung-Kwon Yang, Robert Gardette, Robert Gardette, Julien Matricon, Julien Matricon, Faycal Mouaffak, Faycal Mouaffak, Faycal Mouaffak, Paula Watts, Lene Vimeux, Lene Vimeux, Lene Vimeux, Jong K. Yun, Yuka Imamura Kawasawa, Yuka Imamura Kawasawa, Gary A. Clawson, Elisabeta Blandin, Elisabeta Blandin, Boris Chaumette, Boris Chaumette, Boris Chaumette, Boris Chaumette, Therese M. Jay, Therese M. Jay, Marie-Odile Krebs, Marie-Odile Krebs, Marie-Odile Krebs, Vincent Feuillet, Vincent Feuillet, Vincent Feuillet, Anne Hosmalin, Anne Hosmalin, Anne Hosmalin   +48 more
doaj   +1 more source

Morphology and Nanomechanics of Sensory Neurons Growth Cones following Peripheral Nerve Injury [PDF]

, 2012
A prior peripheral nerve injury in vivo, promotes a rapid elongated mode of sensory neurons neurite regrowth in vitro. This in vitro model of conditioned axotomy allows analysis of the cellular and molecular mechanisms leading to an improved neurite re ...
Vivien Szabo, Scamps, Frédérique, Végh Attila-Gergely, Attila-Gergely Végh, Lucas Olivier, Scamps Frédérique, Ouafa Benzina, Thierry Cloitre, Csilla Gergely, Benzina Ouafa, Szabo, Vivian, Szabo, Vivien, Cloitre, Thierry, Marta Martin, Gergely, Csilla, Frédérique Scamps, Szabo Vivien, Cloitre Thierry, Olivier Lucas, Gergely Csilla, Benzina, Ouafa, Lucas, Olivier, Martin Marta, Martin, Marta, Végh, Attila Gergely   +24 more
core   +2 more sources

Neurite Damage in Patients with Migraine

Neurology International
We examined neurite orientation dispersion and density imaging in patients with migraine. We found that patients with medication overuse headache exhibited lower orientation dispersion than those without.
Yasushi Shibata, Sumire Ishiyama
doaj   +1 more source

MK-STYX Alters the Morphology of Primary Neurons, and Outgrowths in MK-STYX Overexpressing PC-12 Cells Develop a Neuronal Phenotype

Frontiers in Molecular Biosciences, 2017
We previously reported that the pseudophosphatase MK-STYX (mitogen activated kinase phosphoserine/threonine/tyrosine binding protein) dramatically increases the number of what appeared to be primary neurites in rat pheochromocytoma (PC-12) cells; however,
Dallas A. Banks, Arya Dahal, Alexander G. McFarland, Brittany M. Flowers, Brittany M. Flowers, Christina A. Stephens, Benjamin Swack, Ayele Gugssa, Winston A. Anderson, Shantá D. Hinton   +9 more
doaj   +1 more source

NEURITIC FORM OF SYRINGOMYELIA [PDF]

The Journal of Nervous and Mental Disease, 1909
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openaire   +2 more sources

Growth of Neurites toward Neurite– Neurite Contact Sites Increases Synaptic Clustering and Secretion and Is Regulated by Synaptic Activity [PDF]

Cerebral Cortex, 2005
The integrative properties of dendrites are determined by several factors, including their morphology and the spatio-temporal patterning of their synaptic inputs. One of the great challenges is to discover the interdependency of these two factors and the mechanisms which sculpt dendrites' fine morphological details.
Joshua, Cove, Pablo, Blinder, Elia, Abi-Jaoude, Myriam, Lafrenière-Roula, Luc, Devroye, Danny, Baranes   +5 more
openaire   +2 more sources

Probenecid Disrupts a Novel Pannexin 1-Collapsin Response Mediator Protein 2 Interaction and Increases Microtubule Stability

Frontiers in Cellular Neuroscience, 2018
Neurite formation relies on finely-tuned control of the cytoskeleton. Here we identified a novel protein-protein interaction between the ion and metabolite channel protein Pannexin 1 (Panx1) and collapsin response mediator protein 2 (Crmp2), a positive ...
Xiaoxue Xu, Leigh E. Wicki-Stordeur, Juan C. Sanchez-Arias, Mei Liu, Mei Liu, Maria S. Weaver, Catherine S. W. Choi, Leigh A. Swayne, Leigh A. Swayne, Leigh A. Swayne   +9 more
doaj   +1 more source

The development of a ε-polycaprolactone (PCL) scaffold for CNS repair [PDF]

, 2013
Potential treatment strategies for the repair of spinal cord injury (SCI) currently favour a combinatorial approach incorporating several factors, including exogenous cell transplantation and biocompatible scaffolds. The use of scaffolds for bridging the
Boomkamp, S.D., Rebecca Lamond (7128584), Donoghue, P.S., Lamond, R., Nikolaj Gadegaard (1292763), Riehle, M.O., Stephanie D. Boomkamp (7128587), Mathis O. Riehle (1292769), Tao, S., Barnett, S.C., Peter S. Donoghue (7128581), Tao Sun (1255119), Gadegaard, N., Susan C. Barnett (7128590)   +13 more
core   +1 more source