Results 11 to 20 of about 95,315 (199)

Mechanisms of neurite repair [PDF]

open access: yesCurrent Opinion in Neurobiology, 2020
Upon receiving injury signals, neurons can activate various pathways to reduce harm, initiate neuroprotection, and repair damaged neurite without cell death. Here, we review recent progresses in the study of neurite repair focusing on neuronal cell-autonomous mechanisms, including new findings on ion channels that serve as key regulators to initiate ...
Liu, Han-Hsuan, Jan, Yuh-Nung
openaire   +6 more sources

Interplay between cell migration and neurite outgrowth determines SH2B1β-enhanced neurite regeneration of differentiated PC12 cells. [PDF]

open access: yesPLoS ONE, 2012
The regulation of neurite outgrowth is crucial in developing strategies to promote neurite regeneration after nerve injury and in degenerative diseases.
Chia-Ling Wu   +5 more
doaj   +4 more sources

Competitive dynamics during resource-driven neurite outgrowth. [PDF]

open access: yesPLoS ONE, 2014
Neurons form networks by growing out neurites that synaptically connect to other neurons. During this process, neurites develop complex branched trees. Interestingly, the outgrowth of neurite branches is often accompanied by the simultaneous withdrawal ...
J J Johannes Hjorth   +3 more
doaj   +2 more sources

An organized 3D in vitro model for peripheral nerve studies [PDF]

open access: yes, 2013
Three-dimensional cell cultures have been proposed to address the limitations in two-dimensional cell cultures (i.e. lack of relevant architectural features) and very few have developed 3D cell culture methods for peripheral nerve studies. Therefore, the
Daud, Muhammad Fauzi
core   +6 more sources

Imaging of Neurite Network with an Anti-L1CAM Aptamer Generated by Neurite-SELEX

open access: yesJournal of the American Chemical Society, 2018
Neurite outgrowth is the critical step of nervous development. Molecular probes against neurites are essential for evaluation of the nervous system development, compound neurotoxicity, and drug efficacy on nerve regeneration. To obtain a neurite probe, we developed a neurite-SELEX strategy and generated a DNA aptamer, yly12, that strongly binds ...
Linlin Wang   +7 more
core   +4 more sources

Optimization of Neurite Tracing and Further Characterization of Human Monocyte-Derived-Neuronal-like Cells

open access: yesBrain Sciences, 2021
Deficits in neuronal structure are consistently associated with neurodevelopmental illnesses such as autism and schizophrenia. Nonetheless, the inability to access neurons from clinical patients has limited the study of early neurostructural changes ...
Alfredo Bellon   +8 more
doaj   +1 more source

Neurite Outgrowth Assay [PDF]

open access: yesBIO-PROTOCOL, 2016
Neurite outgrowth in culture provides an easy way to determine the effects of a particular substrate or exogenous factor on neuron behavior. Dissociated neurons can be plated on a variety of substrates and the length of the longest neurite outgrowth can be compared.
Angela Filous, Jerry Silver
openaire   +3 more sources

Computer vision profiling of neurite outgrowth mordphodynamics reveals spatio-temporal modularity of Rho GTPase signaling [PDF]

open access: yes, 2014
Neurite outgrowth is essential to build the neuronal processes that produce axons and dendrites that connect the adult brain. In cultured cells, the neurite outgrowth process is highly dynamic, and consists of a series of repetitive morphogenetic sub ...
Fusco, Ludovico
core   +1 more source

Construction of an image recognition algorithm based on neurite outgrowth of human motor neurons and its application in toxicological evaluation

open access: yes陆军军医大学学报, 2023
Objective To develop an MATLAB algorithm for the automated measurement of motor neuron (MN) neurites and apply this algorithm to evaluate the organophosphate flame retardant tris (2-chloroethyl) phosphate (TCEP) on the growth of MN neurites.
DAI Zhiyuan   +5 more
doaj   +1 more source

Local mRNA translation in the regulation of neurite outgrowth [PDF]

open access: yes, 2012
Local mRNA translation allows to synthesize proteins in discrete subcellular locations upon induction by various stimuli, therefore contributing to the control of gene expression in space and in time.
Feltrin, Daniel
core   +1 more source

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