Investigating Connectivity Deficits in Alzheimer's Disease Using a Novel 3D Bioprinted Model Designed to Quantify Neurite Outgrowth. [PDF]
Whitehouse C +6 more
europepmc +1 more source
A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo +18 more
wiley +1 more source
Selection of DNA Aptamers That Promote Neurite Outgrowth in Human iPSC-Derived Sensory Neuron Organoid Cultures. [PDF]
Wilbanks B +7 more
europepmc +1 more source
Deconstruction of Human Age‐Related Cataract Capsules Defines Aging
We generate a comprehensive atlas of age‐related cataracts (ARC) at a single‐cell resolution, encompassing three disease states—mild cataract group (Mild), severe cortical cataract group (Severe_C), and severe nuclear cataract group (Severe_N). We find that ARC involves seven distinct lens capsule cell types, with notable differences in cellular ...
Qiaomei Tang +9 more
wiley +1 more source
Pathogenic PPP2R5D variants disrupt neuronal development and neurite outgrowth in patient-derived neurons that are reversed by allele-specific knockdown. [PDF]
Young RE +6 more
europepmc +1 more source
A murine model of amyloid enhanced tauopathy: progressive changes in tau pathology and behavior
Abstract BACKGROUND Our prior work demonstrated systemic P301L‐tau injections in mice with mature amyloid resulted in several‐fold enhancement of tauopathy compared to non‐transgenic (NTg) littermates. METHODS APP+PS1 mice were injected intravenously with AAV.CAP‐B10 expressing P301L tau (A/P+P301L).
Dylan J. Finneran +4 more
wiley +1 more source
Technical report: Efficient and accurate assessment of neurite outgrowth in spiral ganglion explants using Sholl analysis and repeated measurement ANOVA. [PDF]
Geißler C +4 more
europepmc +1 more source
Bovine Lactoferrin Promotes Neurite Outgrowth in PC12 Cells via the TrkA Receptor. [PDF]
Nagashima D +7 more
europepmc +1 more source
Proanthocyanidins from Ginkgo extract EGb 761<sup>®</sup> improve bioenergetics and stimulate neurite outgrowth <i>in vitro</i>. [PDF]
Lejri I +3 more
europepmc +1 more source
ROCK Inhibitor Enhances Neurite Outgrowth In Vitro and Corneal Sensory Nerve Reinnervation In Vivo. [PDF]
Karpinski BA +5 more
europepmc +1 more source

