Results 261 to 270 of about 87,065 (293)

Procognitive Compounds Promote Neurite Outgrowth

Pharmacology, 2015
<b><i>Background/Aims:</i></b> To this date, the only available drugs for treating Alzheimer's disease are cognitive enhancers, which may improve the cognitive function of patients for a few years while the disease continues to progress.
Matthew, Page, Nathalie, Pacico, Sadia, Ourtioualous, Tania, Deprez, Kyoko, Koshibu   +4 more
openaire   +2 more sources

Role of spastin and protrudin in neurite outgrowth

Journal of Cellular Biochemistry, 2012
AbstractHereditary spastic paraplegia (HSP) is a neurodegenerative disorder characterized by retrograde axonal degeneration that primarily affects long spinal neurons. The gene encoding spastin has a well‐established association with HSP, and protrudin is a known binding partner of spastin.
Chuanling, Zhang, Dan, Li, Yan, Ma, Jinting, Yan, Baiqing, Yang, Peng, Li, Aiping, Yu, Cailing, Lu, Xu, Ma   +8 more
openaire   +2 more sources

Neurite outgrowth and the amyloid protein precursor

Neurobiology of Aging, 1989
Neurite outgrowth in Alzheimer's disease may well be a multifactorial phenomenon. Recent evidence suggests possible roles for the protease inhibitor domain of the 751 amino acid amyloid precursor protein (APP), as well as for the 695 amino acid APP.
openaire   +2 more sources

Graphene substrate for inducing neurite outgrowth

Biochemical and Biophysical Research Communications, 2015
A few recent studies demonstrated that graphene may have cytocompatibility with several cell types. However, when assessing cell behavior on graphene, there has been no precise control over the quality of graphene, number of graphene layers, and substrate surface coverage by graphene.
Jeong Soon, Lee, Alexey, Lipatov, Ligyeom, Ha, Mikhail, Shekhirev, Mohammad Nahid, Andalib, Alexander, Sinitskii, Jung Yul, Lim   +6 more
openaire   +2 more sources

Acetylcholinesterase modulates neurite outgrowth on fibronectin

Biochemical and Biophysical Research Communications, 2007
Acetylcholinesterase (AChE) has been reported to be involved in the modulation of neurite outgrowth. To understand the role played by different domains, we transfected neuroblastoma cells with three constructs containing the invariant region of AChE, differing in the exon encoding the C-terminus and therefore in AChE cellular fate and localization. All
Cinzia Giordano, POIANA, Giancarlo, TOCCO, Gabriella, BIAGIONI, Stefano   +3 more
openaire   +3 more sources

Neurite Outgrowth Inhibitors in Gliotic Tissue

1999
Gliotic tissue is the major obstacle to axon regeneration after CNS injury. We designed tissue culture assays to search for molecules responsible for neurite outgrowth inhibition in gliotic tissue. All the inhibitory activity in injured brain tissue was located in a plasma membrane heparan-sulphate and condroitin-sulphate type-proteoglycan of apparent ...
openaire   +2 more sources

Structurally different lysophosphatidylethanolamine species stimulate neurite outgrowth in cultured cortical neurons via distinct G-protein-coupled receptors and signaling cascades

Biochemical and Biophysical Research Communications, 2021
Takeshi Uemura, Tamotsu Tsukahara, Yoshikazu Matsuda   +2 more
exaly  

Neurite Outgrowth

2017
Tamara IN Nasser, Gaynor E Spencer
openaire   +1 more source

The tumor suppressor protein p53 is required for neurite outgrowth and axon regeneration

EMBO Journal, 2006
Alan I Faden, Simone Di Giovanni, Mahadev Rao   +2 more
exaly  

Core Protein of Chondroitin Sulfate Proteoglycan Promotes Neurite Outgrowth from Cultured Neocortical Neurons

Journal of Neurochemistry, 1991
Shinichi Kohsaka, Atsuhiko Oohira, Katsuaki Kitabatake   +2 more
exaly