Results 81 to 90 of about 87,065 (293)
Advanced Science, EarlyView.Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen +19 more
wiley +1 more source
SCF+G-CSF promotes neurite outgrowth.
, 2013 (A) Measurements of the neurite length 24h after seeding. Note that the neurite length is significantly increased by SCF+G-CSF. (B) SCF+G-CSF promotes neurite extension 48h after plating.
Bin Li (39349) +4 more
core +1 more source
Computer vision profiling of neurite outgrowth dynamics reveals spatiotemporal modularity of Rho GTPase signaling [PDF]
, 2016 Rho guanosine triphosphatases (GTPases) control the cytoskeletal dynamics that power neurite outgrowth. This process consists of dynamic neurite initiation, elongation, retraction, and branching cycles that are likely to be regulated by specific ...
Fua, Pascal +26 more
core +3 more sources
Advanced Science, EarlyView.A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait +7 more
wiley +1 more source
Scientific Reports, 2018 Neurite growth is controlled by a complex molecular signaling network that regulates filamentous actin (F-actin) dynamics at the growth cone. The evolutionarily conserved ezrin, radixin, and moesin family of proteins tether F-actin to the cell membrane ...
Eun-Ju Jin +7 more
doaj +1 more source
Signaling involved in neurite outgrowth of postnatally born subventricular zone neurons in vitro
BMC Neuroscience, 2010 Background Neurite outgrowth is a key process during neuronal migration and differentiation. Complex intracellular signaling is involved in the initiation of neurite protrusion and subsequent elongation.
Monyer Hannah, Khodosevich Konstantin
doaj +1 more source
Pea3 transcription factor promotes neurite outgrowth [PDF]
Frontiers in Molecular Neuroscience, 2014 Pea3 subfamily of E-twenty six transcription factors consist of three major -exhibit branching morphogenesis, the function of Pea3 family in nervous system development and regeneration is only beginning to unfold. In this study, we provide evidence that Pea3 can directs neurite extension and axonal outgrowth in different model systems, and that Serine ...
Kandemir, Basak +8 more
openaire +5 more sources
Competitive dynamics during resource-driven neurite outgrowth. [PDF]
, 2014 Neurons form networks by growing out neurites that synaptically connect to other neurons. During this process, neurites develop complex branched trees. Interestingly, the outgrowth of neurite branches is often accompanied by the simultaneous withdrawal ...
Huibert D Mansvelder +8 more
core +1 more source
Advanced Science, EarlyView.Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang +6 more
wiley +1 more source
Biofunctionalized peptide-based hydrogels provide permissive scaffolds to attract neurite outgrowth from spiral ganglion neurons. [PDF]
, 2017 Cochlear implants (CI) allow for hearing rehabilitation in patients with sensorineural hearing loss or deafness. Restricted CI performance results from the spatial gap between spiral ganglion neurons and the CI, causing current spread that limits ...
Wank, Ute, +16 more
core +1 more source