Results 1 to 10 of about 6,633 (126)

Guide Cells Support Muscle Regeneration and Affect Neuro-Muscular Junction Organization [PDF]

open access: yesInternational Journal of Molecular Sciences, 2021
Muscular regeneration is a complex biological process that occurs during acute injury and chronic degeneration, implicating several cell types. One of the earliest events of muscle regeneration is the inflammatory response, followed by the activation and differentiation of muscle progenitor cells.
Mattia Quattrocelli, Jens van Herck
exaly   +10 more sources

The Muscle Function Deficit Concept and Inflammaging [PDF]

open access: yesBiomedicines
Aging-related muscle dysfunction has been conceptualized through the model of sarcopenia, but it embraces several other characteristics, e.g., dynapenia, myosteatosis, and powerpenia.
Giada Mariano   +4 more
doaj   +2 more sources

Trimetazidine stimulates intracellular Ca2+ transients and zebrafish locomotor activity in spinal neurons [PDF]

open access: yesScientific Reports
The metabolic modulator trimetazidine (TMZ) is an antianginal recently found to improve skeletal muscle performance in mice models of sarcopenia and of amyotrophic lateral sclerosis (ALS).
Sara Bernardi   +4 more
doaj   +2 more sources

THE MODE OF ACTION OF ω-AMINOACYLCHOLINES ON THE NEURO-MUSCULAR JUNCTION

open access: yesThe Japanese Journal of Pharmacology, 1965
The effects of 5-aminopentanoyl- (I), 6-aminohexanoyl- (II) and 7-aminoheptanoyl- (III) cholines and 6-aminohexanoy11-β-methylcholine chlorides on the neuromuscular junction were studied in dogs' and cats' tibial and gastrocnemius muscles.1. Compounds (II) and (III) have the same potency of neuromuscular blocking (one tenth potency of succinylcholine),
ONO, HIROSHI, HASHIMOTO, KOROKU
exaly   +4 more sources

The action of botulinum toxin on the neuro‐muscular junction [PDF]

open access: yesJournal of Physiology, 1949
A S V, BURGEN, F, DICKENS, L J, ZATMAN
exaly   +3 more sources

Drosophila motor neuron retraction during metamorphosis is mediated by inputs from TGF-β/BMP signaling and orphan nuclear receptors. [PDF]

open access: yesPLoS ONE, 2012
Larval motor neurons remodel during Drosophila neuro-muscular junction dismantling at metamorphosis. In this study, we describe the motor neuron retraction as opposed to degeneration based on the early disappearance of β-Spectrin and the continuing ...
Ana Boulanger   +4 more
doaj   +1 more source

Signaling of nicotinic acetylcholine receptors in mononuclear phagocytes

open access: yesPharmacological Research, 2023
Nicotinic acetylcholine receptors are not only expressed by the nervous system and at the neuro-muscular junction but also by mononuclear phagocytes, which belong to the innate immune system.
Katrin Richter, Veronika Grau
doaj   +1 more source

Secreted miRNAs in the tripartite neuromuscular junction [PDF]

open access: yesExRNA, 2019
microRNAs are small, non-coding, single-stranded RNAs that can suppress mRNA translation at the posttranscriptional level by binding to imperfect complementary sequences on mRNA targets and then cause their degradation or hinder protein translation ...
Liangsheng Lu   +6 more
doaj   +1 more source

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