Results 21 to 30 of about 658,405 (249)

Etiology and clinical profile of childhood optic nerve atrophy at a tertiary eye care center in South India

Indian Journal of Ophthalmology, 2014
Background: Optic nerve atrophy is an important ophthalmological sign that may be associated with serious systemic conditions having a significant bearing on the overall morbidity of the child.
Supriya Chinta, Batriti S Wallang, Virender Sachdeva, Amit Gupta, Preeti Patil-Chhablani, Ramesh Kekunnaya   +5 more
doaj   +1 more source

Neuro-ophthalmology as a career

Indian Journal of Ophthalmology, 2014
This essay was written to discuss the reasoning behind the personal decisions made by 2 current neuro-ophthalmology fellows to pursue neuro-ophthalmology as a career.
Arielle Spitze, Nagham Al-Zubidi, Peter Lam, Sushma Yalamanchili, Andrew G Lee   +4 more
doaj   +1 more source

Controversies in neuro-ophthalmology: Steroid therapy for traumatic optic neuropathy

Indian Journal of Ophthalmology, 2014
Background: There is an increase in the incidence of traumatic optic neuropathy (TON) due to increasing urbanization and rapid spurt in the number of motor vehicles on the road.
Rohit Saxena, Digvijay Singh, Vimla Menon   +2 more
doaj   +1 more source

Intellectual and behavioural functioning in boys with Duchenne Muscular Dystrophy : neuropsychological testing and correlation with genotype [PDF]

, 2008
Includes bibliographical references (leaves 76-82).The spectrum of central nervous system manifestations of DMD is less well described than its musculoskeletal aspects. Although international studies have reported intellectual function ranging from above-
Donald, Kirsten Ann Mary
core   +1 more source

The diagnostic yield of neuroimaging in sixth nerve palsy - Sankara Nethralaya Abducens Palsy Study (SNAPS): Report 1

Indian Journal of Ophthalmology, 2014
Aims: The aim was to assess the etiology of sixth nerve palsy and on the basis of our data, to formulate a diagnostic algorithm for the management in sixth nerve palsy. Design: Retrospective chart review. Results: Of the 104 neurologically isolated cases,
Akshay Gopinathan Nair, Selvakumar Ambika, Veena Olma Noronha, Rashmin Anilkumar Gandhi   +3 more
doaj   +1 more source

Treatment modalities of thyroid related orbitopathy

Indian Journal of Ophthalmology, 2014
Aims: The aim was to highlight recent advances in the treatment of thyroid eye disease. Settings and Design: Review article. Materials and Methods: Existing literature and the authors′ experience was reviewed.
Eric S Ahn, Prem S Subramanian
doaj   +1 more source

Neuromuscular junction visualization in paraffin‐embedded thyroarytenoid muscle sections: Expanding options beyond frozen section analysis

Laryngoscope Investigative Otolaryngology
Objective(s) The current gold standard for immunofluorescent (IF) visualization of neuromuscular junctions (NMJs) in muscle utilizes frozen tissue sections with fluorescent conjugated antibodies to demarcate neurons and IF alpha‐bungarotoxin (α‐BTX) to ...
Samuel L. Kaefer, Elizabeth O. Shay, Rachel A. Morrison, Lujuan Zhang, Sherry Voytik‐Harbin, Stacey Halum   +5 more
doaj   +1 more source

Spatial transcriptomics in embryonic mouse diaphragm muscle reveals regional gradients and subdomains of developmental gene expression

iScience
Summary: The murine embryonic diaphragm is a primary model for studying myogenesis and neuro-muscular synaptogenesis, both representing processes regulated by spatially organized genetic programs of myonuclei located in distinct myodomains.
Mehmet Mahsum Kaplan, Maximilian Zeidler, Annabella Knapp, Martina Hölzl, Michaela Kress, Helga Fritsch, Anne Krogsdam, Bernhard E. Flucher   +7 more
doaj   +1 more source

Axonal Transport Defects in a Mitofusin 2 Loss of Function Model of Charcot-Marie-Tooth Disease in Zebrafish.

PLoS ONE, 2013
Charcot-Marie-Tooth disease (CMT) represents a group of neurodegenerative disorders typically characterised by demyelination (CMT1) or distal axon degeneration (CMT2) of motor and sensory neurons.
Anna L Chapman, Ellen J Bennett, Tennore M Ramesh, Kurt J De Vos, Andrew J Grierson   +4 more
doaj   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source