Results 71 to 80 of about 5,499 (175)

Altered methylation pattern of the SRD5A2 gene in the cerebrospinal fluid of post-finasteride patients: a pilot study

Endocrine Connections, 2019
Context: Post-finasteride syndrome (PFS) occurs in patients with androgenic alopecia after suspension of the finasteride treatment, leading to a large variety of persistent side effects.
Roberto Cosimo Melcangi, Livio Casarini, Marco Marino, Daniele Santi, Samantha Sperduti, Silvia Giatti, Silvia Diviccaro, Maria Grimoldi, Donatella Caruso, Guido Cavaletti, Manuela Simoni   +10 more
doaj   +1 more source

Combined liquid and solid-phase extraction improves quantification of brain estrogen content

Frontiers in Neuroanatomy, 2011
Accuracy in quantifying brain-derived steroid hormones (‘neurosteroids’) has become increasingly important for understanding the modulation of neuronal activity, development, and physiology.
Andrew eChao, Andrew eChao, Barney A Schlinger, Luke eRemage-Healey, Luke eRemage-Healey   +4 more
doaj   +1 more source

Differential effects of allopregnanolone and diazepam on social behavior through modulation of neural oscillation dynamics in basolateral amygdala and medial prefrontal cortex

Frontiers in Cellular Neuroscience
Effective treatments for major depressive disorder (MDD) have long been needed. One hypothesis for the mechanism of depression involves a decrease in neuroactive steroids such as allopregnanolone, an endogenous positive allosteric modulator of the γ ...
Yosuke Yawata, Ryoichi Tashima, Hiroyuki Aritomi, Shinji Shimada, Tsukasa Onodera, Teruhiko Taishi, Keiko Takasu, Koichi Ogawa   +7 more
doaj   +1 more source

Developmental and adult stress: effects of steroids and neurosteroids

Stress
In humans, exposure to early life adversity has profound implications for susceptibility to developing neuropsychiatric disorders later in life. Studies in rodents have shown that stress experienced during early postnatal life can have lasting effects on
Isha R. Gore, Elizabeth Gould
doaj   +1 more source

Optimizing Neuroactive Steroid Treatments for Stress-Related Affective Symptoms: Brief Reflections on Patient Population, Timing, and Access. [PDF]

Biol Psychiatry, 2023
Eisenlohr-Moul TA, Barone JC.
europepmc   +1 more source

Neonatal exposure to a neuroactive steroid alters low-frequency oscillations in the subiculum. [PDF]

Exp Biol Med (Maywood), 2023
Fine-Raquet B, Manzella FM, Joksimovic SM, Dietz RM, Orfila JE, Sampath D, Tesic V, Atluri N, Covey DF, Raol YH, Jevtovic-Todorovic V, Herson PS, Todorovic SM.   +12 more
europepmc   +1 more source

Clinical Utility of Zuranolone for Postpartum Depression: A Narrative Review

Neuropsychiatric Disease and Treatment
Athanasia Giannopoulos,1 Joshna Singh,2 Kristina M Deligiannidis1,3 1Division of Psychiatry Research, Zucker Hillside Hospital, Northwell Health, New York, NY, USA; 2Department of Psychiatry, Jacobs School of Medicine and Biomedical Sciences, University ...
Giannopoulos A, Singh J, Deligiannidis KM   +2 more
doaj  

Circulating Neuroactive Steroid Levels in a Patient With Schizophrenia Who Showed Periodic Catatonia. [PDF]

JCEM Case Rep, 2023
Muneoka K, Shirayama Y, Watanabe H, Kimura H.   +3 more
europepmc   +1 more source

Exploring the Impact of the Microbiome on Neuroactive Steroid Levels in Germ-Free Animals. [PDF]

Int J Mol Sci, 2021
Diviccaro S, Caputi V, Cioffi L, Giatti S, Lyte JM, Caruso D, O'Mahony SM, Melcangi RC.   +7 more
europepmc   +1 more source

Loss of CDKL5 Causes Synaptic GABAergic Defects That Can Be Restored with the Neuroactive Steroid Pregnenolone-Methyl-Ether. [PDF]

Int J Mol Sci, 2022
De Rosa R, Valastro S, Cambria C, Barbiero I, Puricelli C, Tramarin M, Randi S, Bianchi M, Antonucci F, Kilstrup-Nielsen C.   +9 more
europepmc   +1 more source