Results 101 to 110 of about 8,012 (216)

The Effects of Neurosteroids, such as Pregnenolone Sulfate and its receptor, TrpM3 in the Retina. [PDF]

, 2019
Pregnenolone sulfate (PregS) is the precursor to all steroid hormones and is produced in neurons in an activity dependent manner. Studies have shown that PregS production is upregulated during certain critical periods of development, such as in the first
Webster, Corey Michael
core  

Peripheral benzodiazepines receptor (PBR) stimulates steroidogenesis: A potential neuroprotective pathway following brain damage

Frontiers in Cellular Neuroscience, 2015
The effects of neuroactive steroids have been highly assessed for their significance on inflammation resolution induced by cytotoxic agents. Steroids are derived from cholesterol, and this regulatory pathway may be a target for possible protective ...
George E. Barreto
doaj   +1 more source

A clickable oxysterol photolabel retains NMDA receptor activity and accumulates in neurons [PDF]

, 2018
Oxysterol analogs that modulate NMDA receptor function are candidates for therapeutic development to treat neuropsychiatric disorders. However, the cellular actions of these compounds are still unclear.
Benz, Ann, Chen, Daniel M, Covey, Douglas F, Mennerick, Steven, Qian, Mingxing, Ziolkowski, Luke, Zorumski, Charles F   +6 more
core   +3 more sources

Neuroesteroides y adicción alcohólica [PDF]

, 2007
Los neuroesteroides (NE) son esteroides sintetizados de novo en el SNC a partir del colesterol independientemente de las fuentes periféricas. NE como la allopregnanolona (AlloP) actúan como moduladores positivos endógenos del receptor GABAA, acción ...
Pallarés Añó, Marc
core  

Electrophysiological Characterization of Sex-Dependent Hypnosis by an Endogenous Neuroactive Steroid Epipregnanolone

Biomolecules
Neuroactive steroids (NAS) have long been recognized for their hypnotic and anesthetic properties in both clinical and preclinical settings. While sex differences in NAS sensitivity are acknowledged, the underlying mechanisms remain poorly understood ...
Tamara Timic Stamenic, Ian Coulter, Douglas F. Covey, Slobodan M. Todorovic   +3 more
doaj   +1 more source

Addiction and the adrenal cortex [PDF]

, 2016
. 7 8 Substantial evidence shows that the hypophyseal-pituitary-adrenal 9 (HPA) axis and corticosteroids are involved in the process of addiction to 10 a variety of agents, and the adrenal cortex has key role.
Brennan, CH, Vinson, GP
core   +2 more sources

Peak visual gamma frequency is modified across the healthy menstrual cycle [PDF]

, 2018
Fluctuations in gonadal hormones over the course of the menstrual cycle are known to cause functional brain changes and are thought to modulate changes in the balance of cortical excitation and inhibition.
McMilllan, Rebecca L., Muthukumaraswamy, Suresh D., Shaw, Alexander D., Singh, Krish D., Sumner, Rachael L., Sundram, Fred   +5 more
core   +2 more sources

Multiple sclerosis lesions exhibit sex-specific steroid changes

Neurobiology of Disease
Sex differences in disease susceptibility and progression in multiple sclerosis (MS) indicate hormonal influences. We previously found sex differences in steroidogenic enzyme expression in mixed active/inactive (mixed) and inactive lesions, suggesting ...
Sabina Luchetti, Matthew R.J. Mason, Philippe Liere, Antoine Pianos, Sara Cossu, Marloes Hofstee, Arja Sluiter, Adelia, Jackelien van Scheppingen, Eleonora Aronica, Michael Schumacher, Inge Huitinga   +11 more
doaj   +1 more source

Effects of estrogen and progesterone on neuroactive steroids and cytokines in patients with suicidality. [PDF]

Psychoneuroendocrinology, 2023
Barone JC, Wenzel E, Alluri V, Moriarity D, Pinna G, Walsh E, Rubinow DR, Morrow AL, Eisenlohr-Moul TA.   +8 more
europepmc   +1 more source

NEUROACTIVE STEROIDS [PDF]

Pediatric Research, 1993
openaire   +1 more source