Results 71 to 80 of about 4,357 (193)
Chemistry &Biodiversity, Volume 23, Issue 5, May 2026.Withanolide D Exhibits Anxiolytic and Memory‐Protective Effects. ABSTRACT This study evaluated the anxiolytic and memory‐protective effects of withanolide D in adult zebrafish (Danio rerio). The compound was administered at doses of 4, 20, and 40 mg/kg and showed no signs of toxicity after 96 h of observation at any of the doses tested.
Cléia Rocha de Sousa Feitosa +17 more
wiley +1 more source
Flavour and Fragrance Journal, Volume 41, Issue 3, Page 656-672, May 2026.The pesticidal potential of Agave angustifolia by assessing its anti‐nematic, antimicrobial, and insecticidal activities, alongside phytochemical profiling. ABSTRACT Plant diseases caused by fungi, bacteria, nematodes, and viruses contribute significantly to annual crop losses and economic hardship. Reliance on chemical pesticides, over a thousand used
Rashika Tamta +7 more
wiley +1 more source
Food Science &Nutrition, Volume 14, Issue 5, May 2026.GLE fractions were prepared from Ganoderma lingzhi using gradient ethanol elution and evaluated for their biological activities. Among the fractions, GLE70 exhibited the strongest antioxidant and hepatoprotective effects. Integrated chemical characterization, network pharmacology, molecular docking, and in vivo validation suggested that GLE70 may exert
Yanjun Chen +7 more
wiley +1 more source
Psychopharmacologic and behavioral effects of neurosteroids
Psychiatry and Clinical Psychopharmacology, 2021 Steroids are known to act via genomic mechanism by binding to their own intracellular receptors. In addition to the steroids which are synthesized in the endocrine organs and able to easily cross to the brain, some steroids have been reported to be ...
Şükrü Kartalcı, Ertuğrul Eşel
doaj
Divergent mechanisms of steroid inhibition in the human ρ1 GABAA receptor
Nature Communicationsρ-type γ-aminobutyric acid-A (GABAA) receptors are widely distributed in the retina and brain, and are potential drug targets for the treatment of visual, sleep and cognitive disorders.
Chen Fan +3 more
doaj +1 more source
Neural Regeneration Research, 2017 The development, maturation and regeneration of Schwann cells (SCs), the main glial cells of the peripheral nervous system, require the coordinate and complementary interaction among several factors, signals and intracellular pathways.
Luca Franco Castelnovo +5 more
doaj +1 more source
Neuroactive steroids and diabetic complications in the nervous system
, 2018 Important complications of diabetes mellitus in the nervous system are represented by diabetic peripheral neuropathy and diabetic encephalopathy. In this context, an important link is represented by neuroactive steroids (i.e., steroids coming from ...
S. Giatti +9 more
core +1 more source
Steroids in childhood epilepsy
Annals of Indian Academy of Neurology, 2006 Treatment of epileptic encephalopathies can be very challenging as most anticonvulsant drugs fail to achieve good seizure control. Steroids are disease modifying as well as anticonvulsant in these conditions.
Ramachandrannair Rajesh
doaj
Progesterone receptor-mediated effects on neuroactive steroids
, 1993 Several 3 alpha-hydroxysteroids accumulate in the brain after local synthesis or after metabolization of steroids that are provided by the adrenals. The 3 alpha-hydroxy ring A-reduced pregnane steroids allopregnanolone and tetrahydrodeoxycorticosterone ...
Reul, J. +16 more
core
BiomoleculesNeuroactive steroids (NAS) have long been recognized for their hypnotic and anesthetic properties in both clinical and preclinical settings. While sex differences in NAS sensitivity are acknowledged, the underlying mechanisms remain poorly understood ...
Tamara Timic Stamenic +3 more
doaj +1 more source