Results 51 to 60 of about 4,357 (193)

Neuroactive steroids: focus on human brain

, 2011
Studies in experimental animals have revealed important roles of neuroactive steroids in the control of central nervous system functions during physiological and pathological conditions, suggesting that they may represent good candidates for the ...
L.M. Garcia-Segura, C. Melcangi, L. M. Garcia Segura, R.C. Melcangi, G. Panzica   +4 more
core   +1 more source

The Neuroprotective Effect of a Waste Byproduct Obtained From Pomegranate (Punica granatum)

Phytotherapy Research, Volume 40, Issue 7, Page 4588-4610, July 2026.
The Effect of a Waste Byproduct Obtained From Pomegranate on Neurodegeneration. ABSTRACT Pomegranate is an exceptional fruit that can have several beneficial effects on human health. The peel of pomegranate, a waste product, should be recovered as it still contains valuable constituents, including phenolic compounds, minerals and fibre. The recovery of
Jessica Maiuolo, Valeria Mazza, Rosamaria Caminiti, Francesca Oppedisano, Saverio Nucera, Salvatore Ragusa, Sara Ilari, Lucia Carmela Passacatini, Luigi Tucci, Giuseppe Trunfio, Vincenzo Mollace, Carolina Muscoli   +11 more
wiley   +1 more source

Treatment of Postpartum Depression with Neurosteroids

Neurologijos seminarai
Neurosteroids, such as allopregnanolone, are primarily synthesized substances in the central nervous system which influence processes occurring in the brain.
Reda Stankevičiūtė, Robertas Strumila
doaj   +3 more sources

Pregnenolone Reduces Stress-Induced Craving, Anxiety, and Autonomic Arousal in Individuals with Cocaine Use Disorder

Biomolecules, 2022
Chronic cocaine use leads to adaptations in stress biology and in neuroactive steroid system. These adaptations are associated with high cocaine craving and increased relapse risk.
Verica Milivojevic, Lily Charron, Nia Fogelman, Gretchen Hermes, Rajita Sinha   +4 more
doaj   +1 more source

Response to Durability of zuranolone in postpartum depression versus major depressive disorder

Psychiatry and Clinical Neurosciences, Volume 80, Issue 7, Page 631-632, July 2026.
This article relates to Response to Durability of zuranolone in postpartum depression versus major depressive disorder.
Masaki Kato, Kazuyuki Nakagome, Takamichi Baba, Takuhiro Sonoyama, Hiroki Fukuju, Ryosuke Shimizu, Juan Carlos Gomez, Tomoko Motomiya, Takeshi Inoue   +8 more
wiley   +1 more source

Data for: Pitfalls of NMDA receptor modulation by neuroactive steroids

, 2021
Data set contains data from a Carousel maze experiment. We evaluated antipsychotic potential of two neuroactive steroids in an animal model of schizophrenia induced by systemic MK-801 application.
Holubova, K (via Mendeley Data)
core   +1 more source

Neuroactive steroids: State of the art and new perspectives

, 2012
Neuroactive steroids include synthetic steroidal compounds and endogenous steroids, produced by endocrine glands (hormonal steroids) or the nervous tissue (neurosteroids), which regulate neural functions.
García-Segura, Luis M., Melcangi, R. C., Mensah-Nyagan, A. G.   +2 more
core   +2 more sources

Integrating Pharmacovigilance Data Mining and Mendelian Randomization to Identify Risk Profiles and Causal Targets of Opioid‐Induced Delirium

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
Opioids like methadone and oxycodone pose a high risk for delirium, particularly in older adults and females. By integrating pharmacovigilance data and Mendelian randomization, we identify key genes (COMT, MYD88, CYP1B1) that influence delirium risk.
Xuetai Chen, Yuting Liu, Mingxuan Zhu, Xingman Chen, Fengyun Liu, Jiahao Jin, Zhiguo Jiang, Bin Qian, Feng Li   +8 more
wiley   +1 more source

Investigation Into the Variations in the Interactions Between Different Selenium Sources and Gut Microbiota

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
Molecular weight and charge of polysaccharides dictate the microbial utilization efficiency of selenium nanoparticles. Chitosan‐based selenium nanoparticles optimize Se metabolism and gut health via specific microbial enrichment. ABSTRACT Selenium (Se) exists in various chemical forms, including inorganic Se, organic Se, and Se nanoparticles (SeNPs ...
Meiyu Yuan, Yihong Li, Zixuan Zhou, Wanting Dai, Xian Cui, Shuang Bi, Xiaoxiao Song   +6 more
wiley   +1 more source

Distinct mechanisms of allopregnanolone and diazepam underlie neuronal oscillations and differential antidepressant effect

Frontiers in Cellular Neuroscience
The rapid relief of depressive symptoms is a major medical requirement for effective treatments for major depressive disorder (MDD). A decrease in neuroactive steroids contributes to the pathophysiological mechanisms associated with the neurological ...
Keiko Takasu, Yosuke Yawata, Ryoichi Tashima, Hiroyuki Aritomi, Shinji Shimada, Tsukasa Onodera, Teruhiko Taishi, Koichi Ogawa   +7 more
doaj   +1 more source