Results 61 to 70 of about 30,473 (233)
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT The ciliopathies are a group of genetic disorders caused by defective function of either the primary cilia (a large number) or the motile cilia (a much smaller number). These have been defined as diseases with mutations in genes encoding individual ciliary or cilia‐associated proteins.
Robert P. Erickson +1 more
wiley +1 more source
eLife, 2018 The long-range coupling within prefrontal-hippocampal networks that account for cognitive performance emerges early in life. The discontinuous hippocampal theta bursts have been proposed to drive the generation of neonatal prefrontal oscillations, yet ...
Joachim Ahlbeck +4 more
doaj +1 more source
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background Olfactory dysfunction is common in aging and an early symptom of neurodegenerative diseases, but how structural (olfactory bulb [OB] volume) and functional (olfactory network [OFN] functional connectivity [FC]) brain features interact to shape odor identification ability remains unclear.
Weiyi Zeng +4 more
wiley +1 more source
Probabilistic Lesion Mapping to Optimize Thalamotomy Targets for Focal Hand Dystonia
Annals of Neurology, EarlyView.Objective Focal hand dystonia (FHD) severely impairs task‐specific motor control, yet the optimal surgical target for stereotactic intervention remains uncertain. This study aimed to identify the precise thalamic lesion site associated with symptomatic improvement and to clarify its network connectivity. Methods We retrospectively analyzed 164 patients
Masahiko Nishitani +12 more
wiley +1 more source
Scientific ReportsThe hippocampal CA2 region has recently been linked to oscillatory activity, spatial navigation, and social behavior. Its predominant neuronal population, CA2 pyramidal neurons (CA2-PNs), critically contributes to hippocampal computations, yet the ...
Pia Kruse +3 more
doaj +1 more source
Sex-specific features of spine densities in the hippocampus
Scientific Reports, 2020 Previously, we found that in dissociated hippocampal cultures the proportion of large spines (head diameter ≥ 0.6 μm) was larger in cultures from female than from male animals.
Nicola Brandt +3 more
doaj +1 more source
The Anatomical Record, EarlyView.Abstract In birds, the neural canal houses a variety of anatomical structures including the spinal cord, meninges, spinal vasculature, and respiratory diverticula. Among these, paramedullary diverticula and the extradural dorsal spinal vein may leave behind osteological correlates in the form of pneumatic foramina and fossae, and a bilobed geometry of ...
Jessie Atterholt +5 more
wiley +1 more source
The Anatomical Record, EarlyView.Abstract A recent debate has emerged between Caspar et al. (2024) and Herculano‐Houzel (2023) on inferring extinct dinosaur cognition by estimating brain neuron counts. While thought‐provoking, the discussion largely overlooks the function of cognition, as well as partly neglects the difficulties involved in estimating neuron numbers, which according ...
Thomas Rejsenhus Jensen +7 more
wiley +1 more source
Studying estrogen effects in an in vitro-model of traumatic brain injury (TBI)
Brain Organoid and Systems Neuroscience JournalIn traumatic brain injury (TBI), mechanical forces trigger a series of detrimental processes in the affected brain, which eventually result in substantial neuronal death. TBI has thus become a leading cause of death and disability worldwide.
Houman Hemmat +3 more
doaj +1 more source
Frontiers in Neuroanatomy, 2017 Poly (ADP-ribose) polymerases (PARPs) are enzymes that catalyze ADP-ribose units transfer from NAD to their substrate proteins. It has been observed that PARP-1 is able to increase both post-ischemic and excitotoxic neuronal death.
Emanuela Paldino +6 more
doaj +1 more source