Results 41 to 50 of about 3,995 (161)

Calcium-driven regulation of voltage-sensing domains in BK channels

eLife, 2019
Allosteric interactions between the voltage-sensing domain (VSD), the Ca2+-binding sites, and the pore domain govern the mammalian Ca2+- and voltage-activated K+ (BK) channel opening.
Yenisleidy Lorenzo-Ceballos, Willy Carrasquel-Ursulaez, Karen Castillo, Osvaldo Alvarez, Ramon Latorre   +4 more
doaj   +1 more source

Interspecies relationships of natural amoebae and bacteria with C. elegans create environments propitious for multigenerational diapause

mSystems
The molecular and physical communication within the microscopic world underpins the entire web of life as we know it. However, how organisms, such as bacteria, amoebae, and nematodes—all ubiquitous—interact to sustain their ecological niches ...
Marcela Serey, Esteban Retamales, Gabriel Ibañez, Gonzalo Riadi, Patricio Orio, Juan P. Castillo, Andrea Calixto   +6 more
doaj   +1 more source

Optochemical modulation of corneal cold nerve terminal impulse activity with a photochromic ion channel blocker

British Journal of Pharmacology, Volume 183, Issue 3, Page 545-559, February 2026.
Background and Purpose The functional organization of corneal cold nerve endings, critical structures in maintaining the ocular surface, remains poorly understood. Here, the photoisomerizable small‐molecule diethylamine‐azobenzene‐quaternary ammonium (DENAQ) was used to photomodulate activity of cold‐sensing nerve terminals in control and chronic tear ...
David Ares‐Suárez, Almudena Iñigo‐Portugués, Enrique Velasco, Susana Quirce, Fernando Aleixandre‐Carrera, Ariadna Díaz‐Tahoces, M. Carmen Acosta, Wan‐Chen Lin, Richard H. Kramer, Carlos Belmonte, Juana Gallar, Victor Meseguer   +11 more
wiley   +1 more source

Artificial intelligence‐powered microscopy: Transforming the landscape of parasitology

Journal of Microscopy, Volume 301, Issue 2, Page 280-329, February 2026.
Abstract Microscopy and image analysis play a vital role in parasitology research; they are critical for identifying parasitic organisms and elucidating their complex life cycles. Despite major advancements in imaging and analysis, several challenges remain. These include the integration of interdisciplinary data; information derived from various model
Mariana De Niz, Sara Silva Pereira, David Kirchenbuechler, Leandro Lemgruber, Constadina Arvanitis   +4 more
wiley   +1 more source

Actualidades en neurociencias.

Colombia Medica, 1985
El enfoque multidisciplinario de los problemas que se presentan en el estudio del sistema nervioso requiere del esfuerzo colectivo para obtener respuestas más completas a los interrogantes que se plantean.
openaire   +1 more source

Association between basal forebrain volume and age in the presenilin‐1 E280A autosomal dominant Alzheimer's disease kindred

Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION The basal forebrain (BF), a key cholinergic hub, undergoes atrophy in Alzheimer's disease (AD), contributing to cognitive decline. However, its age‐related differences and early vulnerability in autosomal dominant AD (ADAD) remain unclear.
Bing He, Paula Ospina Lopera, Alejandro Espinosa, Juan Camilo Becerra, Laura Osorio, Diana Alzate, Sergio Alvarez, Alice Grazia, Stefan J. Teipel, Vincent Malotaux, Catarina Tristão‐Pereira, Meredith C. Rowe, Averi Giudicessi, Yi Su, Yinghua Chen, Sonia Do Carmo, David Aguillón, A. Claudio Cuello, Yakeel T. Quiroz   +18 more
wiley   +1 more source

Neurociencias

, 2022
Este material se dirige a estudiantes de Psicología de los primeros ciclos, durante los que se recibe formación elemental en lo concerniente a las bases biológicas del comportamiento. No obstante, puede ser empleado por psicólogos y profesionales de la salud o neurociencia que quieran consolidar y profundizar los contenidos teóricos.
openaire   +1 more source

Brain volume trajectories in Down syndrome and autosomal dominant Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION It is unknown if neurodegeneration trajectories differ between Down syndrome (DS) and autosomal dominant Alzheimer's disease (ADAD), both of which are genetic forms of Alzheimer's disease (AD). METHODS We compared brain volumes in DS, ADAD, and unaffected family members serving as controls.
James T. Kennedy, Julie K. Wisch, Anna H. Boerwinkle, Peter R. Millar, Nicole S. McKay, Adam M. Brickman, Jasmeer P. Chhatwal, Patricio Chrem Mendez, Bradley T. Christian, Anne Cohen, Carlos Cruchaga, Alisha Daniels, Shaney Flores, Benjamin L. Handen, Sigan L. Hartley, Elizabeth Head, Laura Ibanez, Sharon J. Krisnsky‐McHale, Christian la Fougere, Florence Lai, Charles M. Laymon, Joseph H. Lee, Jae‐Hong Lee, Johannes Levin, Jorge Llibre‐Guerra, David F. Aguillon, Ira T. Lott, Mark Mapstone, Eric McDade, John Morris, Sid E. O'Bryant, Julie C. Price, Michael S. Rafii, Jee Hoon Roh, H. Diana Rosas, Nicole Schupf, Charlene Supnet‐Bell, Chengjie Xiong, Shahid Zaman, Tammie L. S. Benzinger, Brian A. Gordon, Beau M. Ances, the Alzheimer's Brain Consortium – Down Syndrome, and the Dominantly Inherited Alzheimer's Network   +43 more
wiley   +1 more source

Diffusion approximation-based simulation of stochastic ion channels: which method to use?

Frontiers in Computational Neuroscience, 2014
To study the effects of stochastic ion channel fluctuations on neural dynamics, several numerical implementation methods have been proposed. Gillespie’s method for Markov Chains (MC) simulation is highly accurate, yet it becomes computationally intensive
Danilo ePezo, Daniel eSoudry, Patricio eOrio, Patricio eOrio   +3 more
doaj   +1 more source

Neurociencia

, 2021
Neurociencia. Emoción y aprendizaje; es una contribución más para los maestros y maestras que aman y valoran la educación de los niños, púberes, adolescentes y jóvenes; cuyo propósito es compartir experiencias y vivencias de este emocionante camino para encontrar una verdadera educación que mejore la vida de las personas en la forma de ser, pensar ...
openaire   +1 more source