Results 61 to 70 of about 44,972 (227)

Efficacy and Safety of the Use of Interspinous Spacers in the Treatment of Lumbar Spinal Stenosis: Mapping Gap and Scoping Review

open access: yesPain Practice, Volume 26, Issue 5, June 2026.
ABSTRACT Objectives Low back pain is a common pathology in the general population. In people over 60 years of age, it is associated with degenerative changes that cause narrowing of the vertebral canal. Its treatment includes conservative measures and even surgery with decompression and fusion.
Juan Carlos Acevedo‐Gonzalez   +3 more
wiley   +1 more source

Foxa4 favours notochord formation by inhibiting contiguous mesodermal fates and restricts anterior neural development in Xenopus embryos [PDF]

open access: yes, 2014
In vertebrates, the embryonic dorsal midline is a crucial signalling centre that patterns the surrounding tissues during development. Members of the FoxA subfamily of transcription factors are expressed in the structures that compose this centre.
Aguirre, Cecilia Elena   +7 more
core   +4 more sources

Unraveling the Dynamics of Oxytocin in Hypothalamic Neurons

open access: yesTraffic, Volume 27, Issue 2, June 2026.
Oxytocin (OT) plays an important role in regulating social behavior, and dysregulation of the oxytocinergic system leads to social impairments, such as autism spectrum disorder. Central OT release is poorly understood. Using live‐cell imaging to track vesicle trajectories, combined with machine learning‐based classification, the analysis reveals ...
Beatriz Aznar‐Escolano   +6 more
wiley   +1 more source

Preliminary evidence about the effects of meditation on interoceptive sensitivity and social cognition [PDF]

open access: yes, 2013
Background: Interoception refers to the conscious perception of body signals. Mindfulness is a meditation practice that encourages individuals to focus on their internal experiences such as bodily sensations, thoughts, and emotions.
Canales Johnson, Andres   +9 more
core   +3 more sources

GNL3 Orchestrates AR Transcriptional Programs to Drive Castration‐Resistant Prostate Cancer and Immune Evasion

open access: yesAdvanced Science, Volume 13, Issue 26, 8 May 2026.
GNL3 is a novel AR coregulator with dual coactivator and corepressor functions in prostate cancer (PCa). Our study uncovers a previously unrecognized mechanism by which the AR transcriptional complex integrates oncogenic signaling and immune suppression.
Cuiting Zhang   +12 more
wiley   +1 more source

Calcium-driven regulation of voltage-sensing domains in BK channels

open access: yeseLife, 2019
Allosteric interactions between the voltage-sensing domain (VSD), the Ca2+-binding sites, and the pore domain govern the mammalian Ca2+- and voltage-activated K+ (BK) channel opening.
Yenisleidy Lorenzo-Ceballos   +4 more
doaj   +1 more source

Micro‐Stimulation Timing Framed Around an Averaged Theta Period of Stimulation Determines Hippocampal Recruitment in Cued Fear Conditioning

open access: yesHippocampus, Volume 36, Issue 3, May 2026.
ABSTRACT The importance of precise timing of neuronal activity, relative to ongoing slower oscillations, is reshaping the engram theory and our understanding of how memories are encoded and stored. The hippocampal theta‐wave phase‐encoding of neuronal firing predicts behavioral outcomes and cognitive performance in memory tasks.
Paula Gonçalves Vieira Teixeira   +3 more
wiley   +1 more source

Evaluation of the in vitro otoprotective potential of 4-aminopyridine for cisplatin-induced ototoxicity

open access: yesFrontiers in Audiology and Otology
BackgroundCisplatin, an effective chemotherapy, is a cause of ototoxicity. It enters inner ear cells through Organic Cation Transporter 2 (OCT2). Recently, we identified another cochlear transporter, Multidrug and Toxin Extrusion Protein 1 (MATE1); it ...
Sofia Waissbluth   +5 more
doaj   +1 more source

On the normative implications of social neuroscience [PDF]

open access: yes, 2013
En las últimas décadas, la neurociencia y la psicología cognitiva nos ha permitido comenzar a entender la relación entre procesos psicológicos diversos y hasta sobre las bases neurológicas de las creencias, las emociones, los juicios y las decisiones ...
Salles, Arleen
core   +3 more sources

Interspecies relationships of natural amoebae and bacteria with C. elegans create environments propitious for multigenerational diapause

open access: yesmSystems
The molecular and physical communication within the microscopic world underpins the entire web of life as we know it. However, how organisms, such as bacteria, amoebae, and nematodes—all ubiquitous—interact to sustain their ecological niches ...
Marcela Serey   +6 more
doaj   +1 more source

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