Results 41 to 50 of about 4,242 (182)
Calcium-driven regulation of voltage-sensing domains in BK channels
eLife, 2019 Allosteric interactions between the voltage-sensing domain (VSD), the Ca2+-binding sites, and the pore domain govern the mammalian Ca2+- and voltage-activated K+ (BK) channel opening.
Yenisleidy Lorenzo-Ceballos +4 more
doaj +1 more source
Journal of Medical Virology, Volume 98, Issue 7, July 2026.ABSTRACT The Kaposi Sarcoma herpesvirus (KSHV) causes Kaposi sarcoma (KS), primary effusion lymphoma, a lymphoproliferative disease (KSHV‐multicentric Castleman's disease), and a cytokine inflammatory syndrome (KICS). These diseases occur more frequently, though not exclusively, among people living with HIV or other types of immune dysregulation. While
Julian Naipauer +10 more
wiley +1 more source
Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.Abstract Patients with atypical variants of Alzheimer's disease (AD) often present at a younger age with predominantly non‐amnestic impairments and a more aggressive disease course. Historically, individuals with atypical presentations have not been included in large‐scale clinical trials, which typically focus on late‐onset, sporadic amnestic ...
Nick Corriveau‐Lecavalier +36 more
wiley +1 more source
Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.Abstract INTRODUCTION Adverse social conditions across the life course influence brain aging and dementia, yet their compounded impact on clinical phenotypes remains underexplored, particularly in Latin America, where social inequality and dementia burden are high.
Temitope Farombi +36 more
wiley +1 more source
Frontiers in Audiology and OtologyBackgroundCisplatin, an effective chemotherapy, is a cause of ototoxicity. It enters inner ear cells through Organic Cation Transporter 2 (OCT2). Recently, we identified another cochlear transporter, Multidrug and Toxin Extrusion Protein 1 (MATE1); it ...
Sofia Waissbluth +5 more
doaj +1 more source
Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.Abstract INTRODUCTION In Peru, the Global Deterioration Scale is the only available tool for assessing dementia severity. The Spanish translation and cultural adaptation of the Clinical Dementia Rating (CDR) is used locally but requires formal psychometric validation in the Peruvian sociocultural context.
Junior Senador +9 more
wiley +1 more source
mSystemsThe molecular and physical communication within the microscopic world underpins the entire web of life as we know it. However, how organisms, such as bacteria, amoebae, and nematodes—all ubiquitous—interact to sustain their ecological niches ...
Marcela Serey +6 more
doaj +1 more source
The include network: Advancing cross‐linguistic equity in brain health research
Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.Abstract Speech and language measures are increasingly recognized as sensitive, scalable, non‐invasive markers of diverse brain disorders. Yet, current research is overwhelmingly English‐centric, neglecting the world's vast linguistic diversity and undermining these markers’ global applicability.
Adolfo M. García +13 more
wiley +1 more source
, 2021 Neurociencia. Emoción y aprendizaje; es una contribución más para los maestros y maestras que aman y valoran la educación de los niños, púberes, adolescentes y jóvenes; cuyo propósito es compartir experiencias y vivencias de este emocionante camino para encontrar una verdadera educación que mejore la vida de las personas en la forma de ser, pensar ...
openaire +1 more source
Diffusion approximation-based simulation of stochastic ion channels: which method to use?
Frontiers in Computational Neuroscience, 2014 To study the effects of stochastic ion channel fluctuations on neural dynamics, several numerical implementation methods have been proposed. Gillespie’s method for Markov Chains (MC) simulation is highly accurate, yet it becomes computationally intensive
Danilo ePezo +3 more
doaj +1 more source