Results 131 to 140 of about 366,723 (337)

The dopaminergic system in the aging brain of Drosophila

open access: yesFrontiers in Neuroscience, 2010
Drosophila models of Parkinson’s disease are characterised by two principal phenotypes: the specific loss of dopaminergic neurons in the aging brain and defects in motor behavior.
Katherine E White   +2 more
doaj   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

open access: yesAdvanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth   +2 more
wiley   +1 more source

Reply to “A role for GAPDH in apoptosis and neurodegeneration” [PDF]

open access: bronze, 1996
Allen D. Roses   +3 more
openalex   +1 more source

The down-regulation of pank2 gene in zebrafish as a model of Pantothenate Kinase Associated Neurodegeneration. [PDF]

open access: yes, 2016
open9siThe increased iron deposition is a hallmark of many neurodegenerative diseases, but its pathogenic role is still unclear. A strong link between iron and neurodegeneration is evident in a set of heterogeneous neurological disorders, known as ...
ARGENTON, FRANCESCO   +8 more
core  

Molecular Mechanisms of Extracellular Vesicle Biogenesis and Their Impact on the Design of Custom EVs

open access: yesAdvanced Healthcare Materials, EarlyView.
Extracellular vesicles (EVs) are pivotal mediators of intercellular communication and disease, yet the fundamental mechanisms controlling their biogenesis and cargo selection remain unclear. This limitation hinders their diagnostic utility and therapeutic development.
Luís Carvalho Ferraz   +2 more
wiley   +1 more source

Multienzyme (3‐in‐1)‐Mimicking a Single Nucleobase‐Derived Bionanozyme for Versatile Environmental and Biomedical Applications

open access: yesAdvanced Healthcare Materials, EarlyView.
This study reports the development of bioinspired 2D crystalline Bionanozyme derived from a single nucleobase. It effectively mimics multienzyme activity to detect and remove phenolic pollutants, identify disease biomarkers with high sensitivity, and protect cells from oxidative stress.
Subrat Vishwakarma   +8 more
wiley   +1 more source

Dynamic changes in the hippocampal neuronal circuits activity following acute stress revealed by miniature fluorescence microscopy imaging

open access: yesMolecular Brain
Coordinated activity of neuronal ensembles is a basis for information processing in the brain. Recent development of miniscope imaging technology enabled recordings of neuronal circuits activity in vivo in freely behaving animals.
Evgenii Gerasimov   +3 more
doaj   +1 more source

Light‐Harvesting Nanomaterials Based on Dyes for Energy Transfer and Amplified Biosensing

open access: yesAdvanced Materials, EarlyView.
Light harvesting (LH) in plants inspires researchers to develop artificial LH nanomaterials. Here, LH nanomaterials based on organic dyes are reviewed, considering fundamental challenges on aggregation‐caused quenching, excitation energy transfer, and exciton migration length.
Andrey S. Klymchenko   +2 more
wiley   +1 more source

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