Results 291 to 300 of about 366,723 (337)

Tuning Cellular Perception in Pluripotent Stem Cells through Topography, Stiffness, and Patterning

Advanced NanoBiomed Research, EarlyView.
Micro‐ and nanotopographical cues, substrate stiffness, and mechanical patterning synergistically direct pluripotent stem cell fate and function by tuning cellular perception at the biointerface. Pluripotent stem cells (PSCs), comprised of embryonic stem cells and induced PSCs, hold tremendous therapeutic potential.
Yuan Jiang, Jann Harberts, Yaping Chen, Richard J. Williams, Wei Duan, Rasika M. Samarasinghe, Nicolas H. Voelcker, Roey Elnathan   +7 more
wiley   +1 more source

Erratum for: MRI-based Deep Learning Assessment of Amyloid, Tau, and Neurodegeneration Biomarker Status across the Alzheimer Disease Spectrum. [PDF]

Radiology
Lew CO, Zhou L, Mazurowski MA, Doraiswamy PM, Petrella JR, Alzheimer’s Disease Neuroimaging Initiative.   +5 more
europepmc   +1 more source

Comparison of visual and analytic methods of Alzheimer's disease pathologic staging. [PDF]

Alzheimers Dement
Lopresti BJ, Cohen AD, DelBene A, Reese A, Matan C, Gogola A, Chiang M, Snitz BE, Laymon CM, Berman SB, Royse SK, Lopez OL, Villemagne VL.   +12 more
europepmc   +1 more source

Netrin-1: Dual Roles in Neuroinflammation and Neurodegenerative Disease Dynamics. [PDF]

Int J Inflam
Farahani H, Ganji A, Mosayebi G, Monfared ME, Ghazavi A.   +4 more
europepmc   +1 more source

Anatolian ground squirrel (Spermophilus xanthoprymnus) retina: Comparative expression of synaptophysin, NeuN, calbindin‐D28k, parvalbumin, glial fibrillary acidic protein, and Iba‐1 during pre‐hibernation and hibernation

The Anatomical Record, EarlyView.
Abstract Hibernation induces significant molecular and cellular adaptations in the retina to maintain function under reduced metabolic conditions. This study aimed to investigate the expression of neuronal, synaptic, and glial markers in the retina of Spermophilus xanthoprymnus during pre‐hibernation and hibernation periods using immunohistochemical ...
Mehmet Özbek, Feyzullah Beyaz, Mustafa Öztop, Harun Karaca, Ahmet Cabir, Begüm Fatma Kiryar   +5 more
wiley   +1 more source

Transcranial photobiomodulation therapy with 808 nm light changes expression of genes and proteins associated with neuroprotection, neuroinflammation, oxidative stress, and Alzheimer's disease: Whole RNA sequencing of mouse cortex and hippocampus. [PDF]

PLoS One
Li B, Golovynska I, Stepanov YV, Golovynskyi S, Golovynskyi A, Kolesnik D, Stepanova LI, Lai P, Lin F, Qu J.   +9 more
europepmc   +1 more source

From Genome to Geroscience: How DNA Damage Shapes Systemic Decline

BioEssays, EarlyView.
Persistent DNA damage triggers systemic secretory responses including damage‐associated molecular patterns (DAMPs), the senescence‐associated secretory phenotype (SASP), and extracellular vesicles (EVs). This non‐cell‐autonomous signaling disrupts intercellular communication, driving organism‐wide dysfunction and aging, and offering new therapeutic ...
Athanasios Siametis, George A. Garinis
wiley   +1 more source

Cystamine reduces neurodegeneration and epileptogenesis following soman-induced status epilepticus in rats. [PDF]

Exp Biol Med (Maywood)
Biney AK, Schultz CR, Stone MF, Nguyen DA, Wang A, de Araujo Furtado M, Lumley LA.   +6 more
europepmc   +1 more source

Defective Ribosome Recycling: A Bridge Between Translation Fidelity, Organelle Dysfunction, and Diseases

BioEssays, EarlyView.
The Role of Ribosome Recycling in Human Diseases This diagram highlights how disruptions in ribosome translation and recycling can negatively impact cellular and organismal health. Usually, these processes operate efficiently to maintain cellular protein homeostasis.
Foozhan Tahmasebinia, Zhihao Wu
wiley   +1 more source

Relationship Between Depression and Neurodegeneration: Risk Factor, Prodrome, Consequence, or Something Else? A Scoping Review. [PDF]

Biomedicines
Papa D, Ingenito A, von Gal A, De Pandis MF, Piccardi L.   +4 more
europepmc   +1 more source