Results 121 to 130 of about 18,329 (223)
Eye of the Tiger: Looking Beyond Neurodegeneration with Brain Iron Accumulation Disorders. [PDF]
J Pediatr Genet, 2023 Ranganath P, Patil M.
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Hereditary neurodegeneration with brain iron accumulation (clinical case) [PDF]
, 2019 Neurodegeneration with brain iron accumulation is a clinically and genetically heterogeneous group of rare hereditary progressive diseases of the central nervous system with a pronounced accumulation of iron in the basal ganglia and a characteristic ...
Вол, А. Е. +5 more
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Medicinal Research Reviews, Volume 46, Issue 4, Page 1173-1229, July 2026.ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur +6 more
wiley +1 more source
Neurodegeneration with brain iron accumulation.
Folia neuropathologica, 2006 Neurodegeneration with brain iron accumulation (NBIA) describes a group of progressive extrapyramidal disorders with radiographic evidence of focal iron accumulation in the brain, usually in the basal ganglia. Patients previously diagnosed with Hallervorden-Spatz syndrome fall into this category.
Allison, Gregory, Susan J, Hayflick
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Natural Sciences, Volume 6, Issue 3, July 2026.The essential oils of three Origanum species were chemically characterized and evaluated for their antioxidant and enzyme inhibitory activities. The different compositions confer selective bioactivities: O. vulgare exhibits good antioxidant and α‐glucosidase inhibitory activity, O. majorana shows promising tyrosinase inhibition, and O.
Giuseppe Amato +6 more
wiley +1 more source
Amyloid‐β aggregates induce vasculopathy via ferroptosis in brain endothelial cells
Brain Pathology, Volume 36, Issue 4, July 2026.Blood–brain barrier (BBB) disruption is evident in brains with amyloidopathy. In this study, we demonstrate that amyloid β (Aβ) drives abnormal lipid metabolism and lipid droplet formation in brain endothelial cells, leading to lipid peroxidation and ferroptosis.
Suhyeon Son +7 more
wiley +1 more source
Chapter 11 - Neurodegeneration with brain iron accumulation
, 2018 Neurodegeneration with brain iron accumulation (NBIA) describes a heterogeneous group of inherited rare clinical and genetic entities. Clinical core symptoms comprise a combination of early-onset dystonia, pyramidal and extrapyramidal signs with ataxia ...
Houlden, Henry, Wiethoff, Sarah
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ChemBioChem, Volume 27, Issue 11, 15 June 2026.This review reconsiders the amyloid cascade by placing lipid dynamics at its core. It shows that free lipids, governed by critical micellar concentration, act as pathological chaperones that redirect amyloid aggregation toward membrane‐damaging species.
Sofia Serravalle +6 more
wiley +1 more source
Clinical and genetic features of neurodegeneration with brain iron accumulation
Chinese Journal of Contemporary Neurology and Neurosurgery, 2011 DOI: 10.3969/j.issn.1672-6731.2011.06 ...
Yang WANG +3 more
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Eye of the tiger sign in neurodegeneration with brain iron accumulation: a case report
, 2017 Neurodegeneration with brain iron accumulation (NBIA) is a rare autosomal recessive disorder characterized by abnormal accumulation of ferritin in globus pallidus of brain.
Dey, Debasish +6 more
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