Results 181 to 190 of about 18,329 (223)

Coenzyme A mitigates cystine‐deprivation‐induced ferroptosis by suppressing the iron‐starvation response

The FEBS Journal, Volume 293, Issue 11, Page 3288-3302, June 2026.
Cystine (Cys2) deprivation in pancreatic cancer cells induces oxidative stress that destabilizes cytosolic iron–sulfur cluster (ISC) proteins, triggering an iron‐regulatory protein (IRP)‐mediated iron‐starvation response (ISR). This leads to increased iron uptake (via TFRC), an expanded labile iron pool, and ferroptosis.
Mingjun Tan, Yunzhan Li, Lei Sang, Min Wang, Qin Li, Zekun Li, Dongxiao Sun, Xiuchao Wang, Shengyu Yang   +8 more
wiley   +1 more source

Energy Stress‐Induced Neuroprotection Against Ferroptosis in Dopaminergic Neurons

Journal of Neurochemistry, Volume 170, Issue 6, June 2026.
Energy stress via glucose deprivation activates AMPK and protects dopaminergic neurons from ferroptosis by limiting lipid peroxidation. In contrast, glucose availability supports ferroptosis through oxidizable lipid pools. ABSTRACT Ferroptosis, an iron‐dependent form of regulated necrosis, is implicated in the pathogenesis of Parkinson's disease (PD ...
Aurélie Jonneaux, William Laine, Patrice Maboudou, Jérôme Kluza, Marie‐Amandine Bonte, Flore Gouel, David Devos, Philippe Marchetti, Jean‐Christophe Devedjian   +8 more
wiley   +1 more source

Neuregulin‐1 Mitigates Kidney Injury in Humanized Sickle Cell Mice

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
Compared with untreated sickle cell (HbSS) mice, neuregulin‐1 (NRG‐1) treatment reduced plasma heme, lactate dehydrogenase, and pro‐inflammatory cytokines while increasing the proportion of circulating F‐cells. NRG‐1 improved urinary biomarkers of kidney health, decreasing cystatin C and NGAL levels and increased renal repair markers clusterin and ...
William K. Agbozo, Wesley Solomon, Isaac Joe Erskine, Cecilia E. Lekpor, Oguljahan Babayewa, Alaijah Bashi, Adriana Harbuzariu, Aqua Asberry, Driss Adel, Samuel Adjei, Lily Paemka, Solomon F. Ofori‐Acquah, Jonathan K. Stiles   +12 more
wiley   +1 more source

Neurodegeneration with brain iron accumulation

, 2009
Haris Sair, Koushik Tripathy, Keshaw Kumar   +2 more
openaire   +1 more source

Plenary Abstracts Session & Oral Presentations

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Newly characterized forms of neurodegeneration with brain iron accumulation. [PDF]

Curr Neurol Neurosci Rep, 2013
Doorn JM, Kruer MC.
europepmc   +1 more source

The Role of Iron in Neuronal Homeostasis: A Double-Edged Sword. [PDF]

Cells
Sgalletta B, Agostini F, Bisaglia M.
europepmc   +1 more source

Impact of Oxidative Stress-Driven Ferroptosis in Neurodegeneration. [PDF]

Int J Mol Sci
Rafique A, Junaid A, Bakovic M.
europepmc   +1 more source