Results 301 to 310 of about 581,379 (326)
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Radiologic Clinics of North America, 2008
This article outlines the changes seen using various imaging modalities in the normally aging brain and then discusses in detail the changes seen with various pathologic conditions. Entities discussed include primary degenerative dementias, extrapyramidal system diseases, and vascular dementias.
Gallucci M. +3 more
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This article outlines the changes seen using various imaging modalities in the normally aging brain and then discusses in detail the changes seen with various pathologic conditions. Entities discussed include primary degenerative dementias, extrapyramidal system diseases, and vascular dementias.
Gallucci M. +3 more
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Reclassifying neurodegenerative diseases
Nature Biomedical Engineering, 2020Neuropathologies can be classified, on the basis of post-mortem histopathology and by using machine learning, into six transdiagnostic clusters associated with clinical phenotypes.
Pablo, Villoslada +2 more
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Nihon rinsho. Japanese journal of clinical medicine, 2009
Cloning of responsible genes for hereditary neurological diseases has been one of the most important fields in disease genome research since early days. To date, over two hundred genes for degenerative diseases have been identified. The accomplishment of the Human Genome Project and the development of DNA chip technology enabled man to conduct genome ...
Jun, Goto, Seiji, Tsuji
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Cloning of responsible genes for hereditary neurological diseases has been one of the most important fields in disease genome research since early days. To date, over two hundred genes for degenerative diseases have been identified. The accomplishment of the Human Genome Project and the development of DNA chip technology enabled man to conduct genome ...
Jun, Goto, Seiji, Tsuji
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Neuroprotection and Neurodegenerative Disease
Journal of Clinical Neuroscience, 2002This paper will focus on commonalities in the aetiology and pathology in five areas of neurological disease with illustrative examples of therapy. Possibilities of multimodal and neuroprotective therapies in human disease, employing currently available drugs and showing evidence of neuroprotective potential in animal models, are discussed.
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2016
Neurodegenerative diseases (NDDs) are growing in frequency and represent a major threat to public health. Advances in scientific progress have made it clear that NDDs share many underlying processes, including shared intracellular mechanisms such as protein misfolding and aggregation, cell-to-cell prion-like spread, growth factor signaling ...
Jeffrey L. Cummings, Jagan A. Pillai
+4 more sources
Neurodegenerative diseases (NDDs) are growing in frequency and represent a major threat to public health. Advances in scientific progress have made it clear that NDDs share many underlying processes, including shared intracellular mechanisms such as protein misfolding and aggregation, cell-to-cell prion-like spread, growth factor signaling ...
Jeffrey L. Cummings, Jagan A. Pillai
+4 more sources
IDrugs : the investigational drugs journal, 2005
Although this meeting included thousands of presentations spanning the full diversity of neuroscience at the millennium, this report focuses on pharmacological developments of relevance to neurodegenerative diseases.
James Filiano, Ardis L. Olson
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Although this meeting included thousands of presentations spanning the full diversity of neuroscience at the millennium, this report focuses on pharmacological developments of relevance to neurodegenerative diseases.
James Filiano, Ardis L. Olson
openaire +3 more sources
Clinical Chemistry and Laboratory Medicine (CCLM), 2007
Abstract No Abstract ...
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Abstract No Abstract ...
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Innere Medizin (Heidelberg, Germany), 2023
Alexei Verkhratsky, Arthur M. Butt
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Alexei Verkhratsky, Arthur M. Butt
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Reproduction, Fertility and Development, 2011
In the past few decades, a tremendous amount of effort has been invested in developing gene and cell therapies for inherited genetic diseases such as Huntington's disease (HD). However, progress in their clinical application has been very limited. One of the major barriers is the lack of appropriate animal models that allow precise prediction patterns ...
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In the past few decades, a tremendous amount of effort has been invested in developing gene and cell therapies for inherited genetic diseases such as Huntington's disease (HD). However, progress in their clinical application has been very limited. One of the major barriers is the lack of appropriate animal models that allow precise prediction patterns ...
openaire +1 more source