Results 201 to 210 of about 148,627 (233)
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Nature Communications
Prenatal exposure to metals has been associated with impaired neurodevelopment in children, but the detailed molecular mechanisms remain largely unknown.
Ya Xie +7 more
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Prenatal exposure to metals has been associated with impaired neurodevelopment in children, but the detailed molecular mechanisms remain largely unknown.
Ya Xie +7 more
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Chromatin accessibility during human first-trimester neurodevelopment
NatureThe human brain develops through a tightly organized cascade of patterning events, induced by transcription factor expression and changes in chromatin accessibility.
C. Mannens +10 more
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Antiepileptic drugs and neurodevelopment
Current Neurology and Neuroscience Reports, 2006Clinical studies have documented the teratogenic potential of antiepileptic drugs (AEDs). More recent cohort studies have been trying to sort out which AEDs impose the highest risk of teratogenicity. Currently, there is evidence demonstrating an increased risk of major congenital malformations (MCMs) for valproate, phenobarbital, and polytherapy during
Gholam K, Motamedi, Kimford J, Meador
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Fatty Acids and Neurodevelopment
Journal of Pediatric Gastroenterology and Nutrition, 2008ABSTRACTKnowledge of the importance of docosahexaenoic acid (DHA), arachidonic acid (AA), and long‐chain polyunsaturated fatty acids (LCPUFAs) in neurodevelopment was originally obtained from animal studies. These fatty acids are rapidly accreted in brain during the first postnatal year in animal and human infants, and they are found in high ...
J, Belkind-Gerson +4 more
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Norepinephrine, neurodevelopment and behavior
Neurochemistry International, 2020Neurotransmitters play critical roles in the developing nervous system. Among the neurotransmitters, norepinephrine (NE) is in particular postulated to be an important regulator of brain development. NE is expressed during early stages of development and is known to regulate both the development of noradrenergic neurons and the development of target ...
Ehsan, Saboory +2 more
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Histone Acetylation in Neurodevelopment
Current Pharmaceutical Design, 2013Post-translational modification of histones is a primary mechanism through which epigenetic regulation of DNA transcription does occur. Among these modifications, regulation of histone acetylation state is an important tool to influence gene expression.
Antonio, Contestabile, Silvia, Sintoni
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Debugging neurodevelopment disorders
Cell Host & MicrobeGut bacteria are thought to contribute to neurodevelopmental disorders, but whether they are causal or predictive of disease remains unclear. In a prospective longitudinal study of thousands of children, Ahrens et al. generate evidence for the role of the gut microbiome in neurodevelopmental disorders while highlighting important open questions.
Jennie Sotelo-Orozco, Diana H. Taft
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2012
AbstractThis chapter discusses neural induction, organogenesis of the central nervous system, histogenesis of the spinal cord, histogenesis of the brainstem and cerebellum, histogenesis of the cerebral cortex, hemispheric shape and the formation of gyri, and genetic factors during development.
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AbstractThis chapter discusses neural induction, organogenesis of the central nervous system, histogenesis of the spinal cord, histogenesis of the brainstem and cerebellum, histogenesis of the cerebral cortex, hemispheric shape and the formation of gyri, and genetic factors during development.
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Pesticides and child neurodevelopment
Current Opinion in Pediatrics, 2008This review summarizes the recent research on pesticide exposure and child neurobehavioral development with a focus on in-utero exposure to organochlorine and organophosphate pesticides.Recent studies on in-utero exposure to the organochlorine pesticide dichlorodiphenyltrichloroethane and its breakdown product, dichlorodiphenyldichloroethene, indicate ...
Lisa G, Rosas, Brenda, Eskenazi
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Neurodevelopment and Mood Stabilizers
Current Molecular Medicine, 2003Mood disorders and schizophrenia share a number of common properties, including: genetic susceptibility; differences in brain structure and drug based therapy. Some genetic loci may even confer susceptibility for bipolar mood disorder and schizophrenia, and some atypical antipsychotic drugs are used as mood stabilizers.
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