Results 121 to 130 of about 241,752 (284)

Neurodevelopmental Disorder

Psychological Counseling and Psychotherapy, 2019
An approach to define a neurodevelopment disorders, intellectual, neuromotor and autism spectrum disabilities, but also of that wide border area that falls within the current definition of Special Educational Needs (SEDs), through a comparison between neuropsychiatric and pedagogical perspectives, focusing on two complementarity disciplines, which can ...
openaire   +4 more sources

PAIR: Reconstructing Single‐Cell Open‐Chromatin Landscapes for Transcription Factor Regulome Mapping

Advanced Science, EarlyView.
scATAC‐seq analysis is often constrained by limited sequencing depth, extreme sparsity, and pervasive technical missingness. PAIR is a probabilistic framework that restores scATAC‐seq accessibility profiles by directly modeling the native cell–peak bipartite structure of chromatin accessibility.
Yanchi Su, Qi Qi, Yi Fan, Yubo Wang, Gaoyang Hao, Ka‐Chun Wong, Yunhe Wang, Xiangtao Li   +7 more
wiley   +1 more source

Sociodemographic predictors of mental health service utilization among young adults with support in daily living in Sweden: a register-based study

BMC Psychiatry
Background An increasing number of young adults in Sweden are being granted support in daily living through social services. To enhance service planning and resource allocation for this growing group of young service users, we aimed to provide an ...
Jenny Meyer, Sergej Engström, Maria Löthberg, Steve Berggren, Adriana Ramirez, Sonya Girdler, Tatja Hirvikoski, Sven Bölte, Ulf Jonsson   +8 more
doaj   +1 more source

Paternal Caffeine Exposure Programs Offspring Stress Vulnerability via Sperm Dlk1‐Dio3 Imprinting‐Directed Remodeling of a Novel Neural Circuit

Advanced Science, EarlyView.
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu, Gaole Dai, Sen Zhu, Shuai Zhang, Tingting Wang, Yuan Meng, Fang Yang, Xiaoyi Han, Hui Wang, Hao Kou, Dan Xu   +10 more
wiley   +1 more source

Development of a Human 3D Immune‐Competent Neurovascular Model Enabling Time‐Resolved Monitoring of Neuroinflammatory Dynamics and Neuroimmune Interactions

Advanced Science, EarlyView.
Neuroinflammation alters blood–brain barrier integrity and contributes to neurological disorders, yet existing models lack human immune complexity. This study presents a 3D, immune‐responsive platform that reconstructs key neurovascular components and enables real‐time monitoring.
Pavlo Gordiichuk, Jing Bai, Olurotimi A. Bolonduro, Andrew M. Silverman, Robert Madison Green, Jason H. Lasser, Paul W. Fleming, Lishomwa C. Ndhlovu, James F. Saunders, Dmitry Shvartsman   +9 more
wiley   +1 more source

Harnessing Large Language Models to Advance Microbiome Research: From Sequence Analysis to Clinical Applications

Advanced Intelligent Discovery, EarlyView.
Large language models are transforming microbiome research by enabling advanced sequence profiling, functional prediction, and association mining across complex datasets. They automate microbial classification and disease‐state recognition, improving cross‐study integration and clinical diagnostics.
Jieqi Xing, He Wang, Yangyang Sun, Xiaoquan Su, Shunyao Wu   +4 more
wiley   +1 more source

Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics

Advanced Intelligent Discovery, EarlyView.
Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong, Zijian Huang, Xuanwu Wang, Zhenghui Feng, Wei Liu, Bingding Huang   +5 more
wiley   +1 more source

Corpus Callosum Abnormalities at Term-Equivalent Age Are Associated with Language Development at 2 Years’ Corrected Age in Infants Born Very Preterm

Journal of Pediatrics: Clinical Practice
We studied the effect of microstructural abnormalities in the corpus callosum on language development in 348 infants born very prematurely. We discovered that the fractional anisotropy of the corpus callosum anterior midbody was a significant predictor ...
Katsuaki Kojima, MD, PhD, MPH, Julia E. Kline, PhD, Mekibib Altaye, PhD, Beth M. Kline-Fath, MD, Nehal A. Parikh, DO, MS, Armin Allahverdy, PhD, Mekibib Altaye, PhD, Anita Arnsperger, RRT, Traci Beiersdorfer, RN, BSN, Kaley Bridgewater, RT(MR), CNMT, Tanya Cahill, MD, Kim Cecil, PhD, Kent Dietrich, RT, Christen Distler, BSN, RNC-NIC, Juanita Dudley, RN, BSN, Brianne Georg, BS, Meredith Glover, BS, Cathy Grisby, RN, BSN, CCRC, Lacey Haas, RT(MR), CNMT, Karen Harpster, PhD, OT/RL, Lili He, PhD, Scott K. Holland, PhD, V.S. Priyanka Illapani, MS, Kristin Kirker, CRC, Julia E. Kline, PhD, Beth M. Kline-Fath, MD, Hailong Li, PhD, Matt Lanier, RT(MR), RT(R), Stephanie L. Merhar, MD, MS, Greg Muthig, BS, Brenda B. Poindexter, MD, MS, David Russell, JD, Kar Tepe, BSN, RNC-NIC, Leanne Tamm, PhD, Julia Thompson, RN, BSN, Jean A. Tkach, PhD, Hui Wang, PhD, Jinghua Wang, PhD, Brynne Williams, RT(MR), CNMT, Kelsey Wineland, RT(MR), CNMT, Sandra Wuertz, RN, BSN, CCRP, Donna Wuest, AS, Weihong Yuan, PhD   +42 more
doaj   +1 more source

A Robust Deep Temporal Causal Discovery Platform for Single‐Cell Gene Regulatory Network Reconstruction

Advanced Intelligent Discovery, EarlyView.
scTIGER2.0 is a deep‐learning framework that infers gene regulatory networks from single‐cell RNA sequencing data. By integrating correlation, pseudotime ordering, deep learning and bootstrap‐based significance testing, it reduces false positives and reveals directional gene interactions.
Nishi Gupta, Madison Dautle, Shaoqiang Zhang, Yong Chen   +3 more
wiley   +1 more source

Sleep and Neurodevelopmental Disorders [PDF]

Neuropediatrics, 2015
openaire   +2 more sources