Results 1 to 10 of about 470,350 (340)

Somatostatin Analogues in the Treatment of Neuroendocrine Tumors: Past, Present and Future [PDF]

International Journal of Molecular Sciences, 2019
In recent decades, the incidence of neuroendocrine tumors (NETs) has steadily increased. Due to the slow-growing nature of these tumors and the lack of early symptoms, most cases are diagnosed at advanced stages, when curative treatment options are no ...
Amthauer, Holger, Jann, Henning, Kayser, Antonin, Roderburg, Christoph, Stueven, Anna Kathrin, Tacke, Frank, Wetz, Christoph, Wiedenmann, Bertram, Wree, Alexander   +8 more
core   +2 more sources

Recruitment strategies to increase racial and ethnic diversity in anorexia nervosa clinical research

Journal of Eating Disorders, 2023
Objective Inclusion of underrepresented racial and ethnic groups in eating disorder (ED) research is a critical unmet need, but evidence-based recruitment strategies are lacking.
Julianne Strauch, Alexandra Agnew, Erinne Meenaghan, Karen K. Miller, Melanie S. Haines   +4 more
doaj   +1 more source

Pasireotide for Refractory Hypoglycemia in Malignant Insulinoma- Case Report and Review of the Literature

Frontiers in Endocrinology, 2022
Malignant insulinomas are functional neuroendocrine tumors of the pancreas and the primary cause of tumor-related hypoglycemia. Malignant insulinoma is rare and has a poor prognosis.
Sandrine Oziel-Taieb, Jemima Maniry-Quellier, Brice Chanez, Flora Poizat, Jacques Ewald, Patricia Niccoli   +5 more
doaj   +1 more source

Methylmalonic acid promotes colorectal cancer progression via activation of Wnt/β-catenin pathway mediated epithelial–mesenchymal transition

Cancer Cell International, 2023
Background It has been manifested in several studies that age-related metabolic reprogramming is associated with tumor progression, in particular, colorectal cancer (CRC).
Chunhua Hu, Mujie Ye, Jianan Bai, Pengfei Liu, Feiyu Lu, Jinhao Chen, Ping Yu, Tiaotiao Chen, Xiaoting Shi, Qiyun Tang   +9 more
doaj   +1 more source

Down-regulated FTO and ALKBH5 co-operatively activates FOXO signaling through m6A methylation modification in HK2 mRNA mediated by IGF2BP2 to enhance glycolysis in colorectal cancer

Cell & Bioscience, 2023
Background N6-methyladenosine (m6A) modification is the most abundant reversible methylation modification in eukaryotes, and it is reportedly closely associated with a variety of cancers progression, including colorectal cancer (CRC).
Mujie Ye, Jinhao Chen, Feiyu Lu, Minghui Zhao, Suwen Wu, Chunhua Hu, Ping Yu, Jingbao Kan, Jianan Bai, Ye Tian, Qiyun Tang   +10 more
doaj   +1 more source

Low bone mineral density is found in low weight female youth with avoidant/restrictive food intake disorder and associated with higher PYY levels

Journal of Eating Disorders, 2023
Background Avoidant/restrictive food intake disorder (ARFID) is a restrictive eating disorder commonly associated with medical complications of undernutrition and low weight.
Aluma Chovel Sella, Kendra R. Becker, Meghan Slattery, Kristine Hauser, Elisa Asanza, Casey Stern, Megan Kuhnle, Nadia Micali, Kamryn T. Eddy, Madhusmita Misra, Jennifer J. Thomas, Elizabeth A. Lawson   +11 more
doaj   +1 more source

ALKBH5 enhances lipid metabolism reprogramming by increasing stability of FABP5 to promote pancreatic neuroendocrine neoplasms progression in an m6A-IGF2BP2-dependent manner

Journal of Translational Medicine, 2023
The process of post-transcriptional regulation has been recognized to be significantly impacted by the presence of N6-methyladenosine (m6A) modification.
Jinhao Chen, Mujie Ye, Jianan Bai, Zhihui Gong, Lijun Yan, Danyang Gu, Chunhua Hu, Feiyu Lu, Ping Yu, Lin Xu, Yan Wang, Ye Tian, Qiyun Tang   +12 more
doaj   +1 more source

Duodenal carcinoid tumour – a case report [PDF]

, 2020
Duodenal carcinoids are rare tumours of the small intestine with heterogenous clinical and pathological characteristics. The long-term prognosis is very good if discovered in the early stages.
Alexescu, Teodora Gabriela, Buchman, Cristina, Domsa, Iacob, Milaciu, Mircea, Negrean, Vasile, Orasan, Olga Hilda, Para, Ioana, Perne, Mirela Georgiana   +7 more
core   +2 more sources

Neural activation of regions involved in food reward and cognitive control in young females with anorexia nervosa and atypical anorexia nervosa versus healthy controls

Translational Psychiatry, 2023
Anorexia nervosa (AN) and atypical AN (AtypAN) are complex neurobiological illnesses that typically onset in adolescence with an often treatment-refractory and chronic illness trajectory.
Kamryn T. Eddy, Franziska Plessow, Lauren Breithaupt, Kendra R. Becker, Meghan Slattery, Christopher J. Mancuso, Alyssa M. Izquierdo, Avery L. Van De Water, Danielle L. Kahn, Melissa J. Dreier, Seda Ebrahimi, Thilo Deckersbach, Jennifer J. Thomas, Laura M. Holsen, Madhusmita Misra, Elizabeth A. Lawson   +15 more
doaj   +1 more source

Point-Substitution of Phenylalanine Residues of 26RFa Neuropeptide: A Structure-Activity Relationship Study

Molecules, 2021
26RFa is a neuropeptide that activates the rhodopsin-like G protein-coupled receptor QRFPR/GPR103. This peptidergic system is involved in the regulation of a wide array of physiological processes including feeding behavior and glucose homeostasis. Herein,
Benjamin Lefranc, Karima Alim, Cindy Neveu, Olivier Le Marec, Christophe Dubessy, Jean A. Boutin, Julien Chuquet, David Vaudry, Gaëtan Prévost, Marie Picot, Hubert Vaudry, Nicolas Chartrel, Jérôme Leprince   +12 more
doaj   +1 more source