Results 1 to 10 of about 75,268 (264)

When Immunophenotype Is Not Identity: A Clinicopathological Review of Neuroendocrine Differentiation in Tumors of the Female Genital Tract [PDF]

Diagnostics
Neuroendocrine differentiation in tumors of the female genital tract is an uncommon but diagnostically consequential finding. Its interpretation is challenging because neuroendocrine marker expression does not necessarily define a neuroendocrine neoplasm.
Catalin-Bogdan Satala, Alina-Mihaela Gurau, Gabriela Patrichi, Roxana-Cristina Mehedinti, Andy Radu Leibovici, Gabriela Gurau   +5 more
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Extragonadal yolk sac tumor of the ureter with neuroendocrine differentiation: A case report [PDF]

Urology Case Reports
Extragonadal germ cell tumors in the urinary tract are exceptionally rare, with only a small number of cases documented in the literature. Although these neoplasms exhibit considerable histologic heterogeneity, neuroendocrine differentiation within these
Masato Takanashi, Jiro Kumagai, Takayuki Murakami   +2 more
doaj   +2 more sources

Point-Substitution of Phenylalanine Residues of 26RFa Neuropeptide: A Structure-Activity Relationship Study

Molecules, 2021
26RFa is a neuropeptide that activates the rhodopsin-like G protein-coupled receptor QRFPR/GPR103. This peptidergic system is involved in the regulation of a wide array of physiological processes including feeding behavior and glucose homeostasis. Herein,
Benjamin Lefranc, Karima Alim, Cindy Neveu, Olivier Le Marec, Christophe Dubessy, Jean A. Boutin, Julien Chuquet, David Vaudry, Gaëtan Prévost, Marie Picot, Hubert Vaudry, Nicolas Chartrel, Jérôme Leprince   +12 more
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Achievement of complete in vitro spermatogenesis in testicular tissues from prepubertal mice exposed to mono- or polychemotherapy

Scientific Reports, 2022
The assessment of the impact of chemotherapies on in vitro spermatogenesis in experimental models is required before considering the application of this fertility restoration strategy to prepubertal boys who received these treatments before testicular ...
Marion Delessard, Laura Stalin, Aurélie Rives-Feraille, Laura Moutard, Justine Saulnier, Ludovic Dumont, Nathalie Rives, Christine Rondanino   +7 more
doaj   +1 more source

Intermittent hypoxia in a mouse model of apnea of prematurity leads to a retardation of cerebellar development and long-term functional deficits

Cell & Bioscience, 2022
Background Apnea of prematurity (AOP) is caused by respiratory control immaturity and affects nearly 50% of premature newborns. This pathology induces perinatal intermittent hypoxia (IH), which leads to neurodevelopmental disorders.
S. Leroux, A. Rodriguez-Duboc, A. Arabo, M. Basille-Dugay, D. Vaudry, D. Burel   +5 more
doaj   +1 more source

Blood Levels of Neuropeptide 26RFa in Relation to Anxiety and Aggressive Behavior in Humans—An Exploratory Study

Brain Sciences, 2023
26RFa, also referred to as QRFP, is a hypothalamic neuropeptide mainly known for its role in the regulation of appetite and glucose metabolism. Its possible relevance to emotional regulation is largely unexplored.
Henning Værøy, Saloua Takhlidjt, Yamina Cherifi, Emilie Lahaye, Nicolas Chartrel, Serguei O. Fetissov   +5 more
doaj   +1 more source

Immunoglobulin G is a natural oxytocin carrier which modulates oxytocin receptor signaling: relevance to aggressive behavior in humans

Discover Mental Health, 2023
Oxytocin is a neuropeptide produced mainly in the hypothalamus and secreted in the CNS and blood. In the brain, it plays a major role in promoting social interactions.
Henning Værøy, Emilie Lahaye, Christophe Dubessy, Magalie Benard, Marion Nicol, Yamina Cherifi, Saloua Takhlidjt, Jean-Luc do Rego, Jean-Claude do Rego, Nicolas Chartrel, Sergueï O. Fetissov   +10 more
doaj   +1 more source

Intranasal Administration of PACAP Is an Efficient Delivery Route to Reduce Infarct Volume and Promote Functional Recovery After Transient and Permanent Middle Cerebral Artery Occlusion

Frontiers in Endocrinology, 2021
Intranasal (IN) administration appears to be a suitable route for clinical use as it allows direct delivery of bioactive molecules to the central nervous system, reducing systemic exposure and sides effects.
Asma Cherait, Asma Cherait, Asma Cherait, Julie Maucotel, Julie Maucotel, Benjamin Lefranc, Benjamin Lefranc, Jérôme Leprince, Jérôme Leprince, David Vaudry, David Vaudry   +10 more
doaj   +1 more source

Cell-penetrating, antioxidant SELENOT mimetic protects dopaminergic neurons and ameliorates motor dysfunction in Parkinson's disease animal models

Redox Biology, 2021
Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor dysfunction for which there is an unmet need for better treatment options.
Ifat Alsharif, Loubna Boukhzar, Benjamin Lefranc, David Godefroy, Juliette Aury-Landas, Jean-Luc do Rego, Jean-Claude do Rego, Frédéric Naudet, Arnaud Arabo, Abdeslam Chagraoui, David Maltête, Abdelhamid Benazzouz, Catherine Baugé, Jérôme Leprince, Abdel G. Elkahloun, Lee E. Eiden, Youssef Anouar   +16 more
doaj   +1 more source

Gut Microbiota–Brain Axis in Regulation of Feeding Behavior

Microorganisms, 2023
The survival of microorganisms inhabiting the intestinal tract depends on the nutrients provided by the host, with the latter obtaining them through food intake.
Sergueï O. Fetissov
doaj   +1 more source