Results 21 to 30 of about 75,268 (264)
Frontiers in Pharmacology, 2022 Huntington’s disease (HD) is a hereditary neurodegenerative disorder caused by the expression of mutant huntingtin (mHtt). One of the main features of HD is the degeneration of the striatum that leads to motor discoordination. Pituitary adenylate cyclase-
Irene Solés-Tarrés +11 more
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Trichilemmal carcinoma with neuroendocrine differentiation [PDF]
Clinical and Experimental Dermatology, 2008 We report a 12-mm nodular, cream-coloured skin lesion that appeared on the left nasal ala in an 81-year-old man. This trabecular infiltrative tumour showed keratin microcysts, stromal hyalization, cytoarchitectural malignancy features, colonizing melanocytes, and immunoexpression of epithelial membrane antigen, cytokeratin 15/20, chromogranin ...
Diaz-Cano, Salvador J., L Pozo-Garcia
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Frontiers in Endocrinology, 2018 The European eel (Anguilla anguilla) presents a blockade of sexual maturation at a prepubertal stage due to a deficient production of gonadotropins.
Jérémy Pasquier +10 more
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Biomolecules, 2021 Biomolecules has launched a Special Issue entitled “Dopamine D3 Receptor: Contemporary Views of Its Function and Pharmacology for Neuropsychiatric Diseases [...]
Philippe De Deurwaerdère +1 more
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Frontiers in Psychiatry, 2019 Adrenocorticotropic hormone together with arginine vasopressin and oxytocin, the neuropeptides regulating the stress response and the hypothalamic-pituitary-adrenal axis activity, are known to modulate aggressive behavior.
Henning Vaeroy +2 more
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Cellular neurothekeoma with neuroendocrine differentiation
Dermatology Online Journal, 2011 We report a case of cellular neurothekeoma with unusual clinicopathological features in which neuroendocrine markers, determined by immunohistochemistry were observed. Histologically, the tumor showed a micronodular architecture with hypercellular lobules composed of slightly spindled to epithelioid cells, with nuclear atypia or pleomorphism and ...
D'Antonio A. +4 more
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Journal of Medical Case Reports, 2020 Background Metastatic neuroendocrine carcinoma often presents as carcinoma of unknown primary. Although most cases display immunohistochemical positivity for neuroendocrine markers, subsets of cases display reduced or negative expression for some of ...
Carl Christofer Juhlin +2 more
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Is neuroendocrine differentiation a prognostic factor in poorly differentiated colorectal cancer?
World Journal of Surgical Oncology, 2017 Background To determine the prognostic relevance of neuroendocrine differentiation in poorly differentiated colorectal cancer. Methods The clinicopathological features and survival of 70 patients with poorly differentiated colorectal cancer were analyzed
Yue Chen +3 more
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Does Biochemical Life Exist for a Receptor Agonist Outside Its Receptor? The Case of Melatonin
ReceptorsMelatonin is reported to exert two types of actions: those based on its interaction with cognate receptors (characterized by very high affinities—1 nM and below), and those mediated by unknown targets (characterized by high concentrations—100 µM and ...
Jean A. Boutin, Jérôme Leprince
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Neuroendocrine differentiation in prostate cancer
Vojnosanitetski pregled, 2004 Background. In numerous recent studies attention has been focused to neuroendocrine differentiation (NED) in prostate cancer (PC). Focal NED is present in almost all PCs, but it is prominent in only 5-10% of the carcinomas. The prognostic significance of focal NED in PC is controversial, but current evidence suggests its influence on the onset and/or ...
Snezana Cerovic +3 more
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