Aberrant synaptophysin expression in classic Hodgkin lymphoma
Background Synaptophysin is an immunohistochemical marker for neuroendocrine differentiation and is widely used in pathologic diagnosis. Its expression in malignant lymphoma has not yet been described.
Soyoung Im +3 more
doaj +3 more sources
Case Report: Feline adrenal pheochromocytoma with a synaptophysin-positive, chromogranin A–negative immunophenotype [PDF]
Pheochromocytoma is a rare adrenal medullary neoplasm in cats, with limited published cases and diagnostic challenges due to variable clinical presentation.
Jihyun Kim, Sooa Yoon, Seungjin Lee
doaj +2 more sources
Abiraterone Acetate Affects Gene Expression Profile in a Human Male Neuronal Cell Line: Potential Mechanism for Cognitive Deficits with Prostate Cancer Therapy [PDF]
Background and Objectives: Cornerstone therapies for metastatic prostate cancer include androgen deprivation and androgen receptor pathway inhibition, but cognitive impairment is a recognized, life-altering potential adverse effect of this treatment ...
Shelly Gulkarov +6 more
doaj +2 more sources
Post-translational processing of synaptophysin in the rat retina is disrupted by diabetes. [PDF]
Synaptophysin, is an abundant presynaptic protein involved in synaptic vesicle recycling and neurotransmitter release. Previous work shows that its content is significantly reduced in the rat retina by streptozotocin (STZ)-diabetes. This study tested the
Travis S D'Cruz +3 more
doaj +1 more source
Single Centre Based Clinicopathological Experience of Adrenal Tumours Including Some Rare Entities [PDF]
Adrenal tumours are relatively uncommon neoplasms, broadly divided into adrenal cortical and medullary tumours. They show bimodal age distribution.
Moumita Maiti +2 more
doaj +1 more source
Clinico-epidemiological Profile of Incidentally Detected Gastrointestinal Neuroendocrine Tumours on Gastrointestinal Endoscopy: A Retrospective Study [PDF]
Introduction: Neuroendocrine tumours (NETs) are rare tumours, with the Gastrointestinal (GI) tract and the lung as the most common sites with indolent course.
AK Koushik +3 more
doaj +1 more source
A Fine Balance of Synaptophysin Levels Underlies Efficient Retrieval of Synaptobrevin II to Synaptic Vesicles. [PDF]
Synaptobrevin II (sybII) is a vesicular soluble NSF attachment protein receptor (SNARE) protein that is essential for neurotransmitter release, and thus its correct trafficking to synaptic vesicles (SVs) is critical to render them fusion competent.
Sarah L Gordon +3 more
doaj +1 more source
Effects of citicoline administration on synaptic proteins in rapid eye movement sleep-deprived rats [PDF]
Objective(s): Sleep has a pivotal role in learning-memory and sleep deprivation (SD) negatively affects synaptic functioning. Cytidine-5-diphosphocholine (Citicoline) has been known to improve learning and memory functions.
Ayşen Cakir +5 more
doaj +1 more source
Complementary to synaptophysin and chromogranin A, insulinoma‐associated protein 1 (INSM1) has emerged as a sensitive marker for the diagnosis of neuroendocrine neoplasms.
Anne‐Sophie Litmeyer +16 more
doaj +1 more source
Synaptophysin immunoreactivity in adrenocortical adenomas: a correlation between synaptophysin and CYP17A1 expression [PDF]
Design and methodsThe adrenal cortex is not considered to be an intrinsic part of the diffuse neuroendocrine system, but adrenocortical neoplasms possess neuroendocrine properties. In this study, we examined synaptophysin (SYP) and neural cell adhesion molecule (NCAM) expression in adrenocortical adenomas in relation to adrenal function ...
Kazuto, Shigematsu +7 more
openaire +2 more sources

