Results 11 to 20 of about 47,565 (201)
Synaptophysin Is a Reliable Marker for Axonal Damage [PDF]
Journal of Neuropathology & Experimental Neurology, 2017 Synaptophysin is an abundant membrane protein of synaptic vesicles. The objective of this study was to determine the utility of identifying synaptophysin accumulations (spheroids/ovoids/bulbs) in CNS white matter as an immunohistochemical marker of axonal damage in demyelinating and neuroinflammatory conditions.
Gudi, Viktoria +11 more
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Synaptophysin immunoreactivity in the cat cochlear nuclei. [PDF]
Histology and histopathology, 1998 The presence of synaptophysin, a presynaptic Ca2+ binding glycoprotein, has been analyzed in the cochlear nucleus complex of the adult cat using an antisynaptophysin monoclonal antibody. Synaptophysin immunoreactivity was differently distributed between regions of cochlear nuclei.
Gil-Loyzaga, P. +2 more
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Clinical Ophthalmology, 2018 José Carlos López López,1 Nieves Fernández Alonso,1 Juan Cuevas Álvarez,1,2 Tomás García-Caballero,2 José Carlos Pastor Jimeno3 1Ocular Pathology Laboratory, Instituto Universitario de ...
López López JC +4 more
doaj +1 more source
Neuroendocrine cancer of the prostate. Two case reports
Journal of Men's Health, 2022 Background: Neuroendocrine cancer of the prostate can present in diverse clinical pictures, potentially hampering the diagnosis and probably leading to underdiagnosis.
Tamás Kullmann +3 more
doaj +1 more source
Room for Two: The Synaptophysin/Synaptobrevin Complex [PDF]
Frontiers in Synaptic Neuroscience, 2021 Synaptic vesicle release is regulated by upwards of 30 proteins at the fusion complex alone, but disruptions in any one of these components can have devastating consequences for neuronal communication. Aberrant molecular responses to calcium signaling at the pre-synaptic terminal dramatically affect vesicle trafficking, docking, fusion, and release. At
Dustin N. White, Michael H. B. Stowell
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Synaptophysin and synaptoporin expression in the developing rat olfactory system [PDF]
, 1993 The expressions of two closely related synaptic vesicle antigens synaptophysin and synaptoporin were examined in the olfactory system of the adult rat and during pre- and postnatal development.
Traurig, H. +7 more
core +1 more source
Differential expression of synaptophysin and synaptoporin during pre- and postnatal development of the hippocampal network [PDF]
, 1994 The closely related synaptic vesicle membrane proteins synaptophysin and synaptoporin are abundant in the hippocampal formation of the adult rat. But the prenatal hippocampal formation contains only synaptophysin, which is first detected at embryonic day
M. Gratzl +11 more
core +1 more source
Synaptophysin Immunoreactivity as Marker for Fetal Hippocampal and Cortical Development
Pediatric Neurology Briefs, 2010 Researchers at University of Calgary Faculty of Medicine and Alberta Children's Hospital, Canada, have studied synaptophysin immunoreactivity (sIR) in postmortem sections of 162 normal human fetal and neonatal brains of both sexes from 6 to 41 weeks ...
J Gordon Millichap
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Amyloid-β acts as a regulator of neurotransmitter release disrupting the interaction between synaptophysin and VAMP2. [PDF]
, 2012 BACKGROUND: It is becoming increasingly evident that deficits in the cortex and hippocampus at early stages of dementia in Alzheimer's disease (AD) are associated with synaptic damage caused by oligomers of the toxic amyloid-β peptide (Aβ42).
Russell, CL +17 more
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Ontogeny of synaptophysin and synaptoporin in the central nervous system [PDF]
, 1993 The expression of the synaptic vesicle antigens synaptophysin (SY) and synaptoporin (SO) was studied in the rat striatum, which contains a nearly homogeneous population of GABAergic neurons. In situ hybridization revealed high levels of SY transcripts in
Marquéze-Pouey, B. +15 more
core +1 more source