Results 21 to 30 of about 47,565 (201)
Medulloblastoma (MB) is the most common malignant brain tumor in childhood. The alterations found include: presence of oncoproteins p53 and HER2, elevated mitotic index, and presence of neuronal differentiation. The aim of this study was to determine the
Rosalva Thereza Meurer +6 more
doaj +1 more source
Pure small cell neuroendocrine carcinoma of urinary bladder: A case report
Small cell neuroendocrine carcinoma of the bladder is rare. We report a case of small cell carcinoma of the bladder with extensive regional lymph node metastases who underwent radical cystoprostatectomy and subsequent adjuvant systemic chemotherapy and ...
Abbas Eshraghi +5 more
doaj +1 more source
Correlation with basic differentiation processes of neurons [PDF]
The development of the spinal cord involves the proliferation of neurons, their migration to well-defined areas, fiber outgrowth and synapse formation. The present study was designed to correlate the spatiotemporal pattern of expression of synaptophysin,
Lahr, G. +3 more
core +1 more source
Immunohistochemistry and Radiomic Features for Survival Prediction in Small Cell Lung Cancer
Background: The aim of the study was to evaluate the role of different immunohistochemical and radiomics features in patients with small cell lung cancer (SCLC).Methods: Consecutive patients with histologically proven SCLC with limited (n = 47, 48%) or ...
Eleni Gkika +25 more
doaj +1 more source
Ndufs4 ablation decreases synaptophysin expression in hippocampus [PDF]
AbstractAltered function of mitochondrial respiratory chain in brain cells is related to many neurodegenerative diseases. NADH Dehydrogenase (Ubiquinone) Fe-S protein 4 (Ndufs4) is one of the subunits of mitochondrial complex I and its mutation in human is associated with Leigh syndrome.
Subrata Kumar Shil +9 more
openaire +3 more sources
Hydrogen Inhalation Protects against Ototoxicity Induced by Intravenous Cisplatin in the Guinea Pig
Introduction: Permanent hearing loss and tinnitus as side-effects from treatment with the anticancer drug cisplatin is a clinical problem. Ototoxicity may be reduced by co-administration of an otoprotective agent, but the results in humans have so far ...
Anette E. Fransson +5 more
doaj +1 more source
Effects of Environmental Enrichment in Maternally Separated Rats: Age and Sex-Specific Outcomes
Maternal separation (MS) early in life is related to an increase in anxiety and depressive-like behaviors and neurobiological alterations mostly related to alterations in hypothalamic pituitary adrenal (HPA) axis reactivity. Environmental enrichment (EE)
Raura Doreste-Mendez +7 more
doaj +1 more source
Fast repetitive synaptic transmission depends on efficient exocytosis and retrieval of synaptic vesicles around a presynaptic active zone. However, the functional organization of an active zone and regulatory mechanisms of exocytosis, endocytosis and ...
Junichiro Funahashi +2 more
doaj +1 more source
Effect of Bone Marrow-Derived Mesenchymal Stem Cells on the Hippocampal CA1 Area of Aluminium Chloride-Induced Alzheimer's Disease in Adult Male Albino Rat: A Histological and Immunohistochemical Study [PDF]
Introduction: Alzheimer’s disease (AD) is the commonest cause of dementia among the elderly. Aluminium is a toxic metal that primarily affects the hippocampus.
Eman El-Beltagi +4 more
doaj +1 more source
IntroductionIn Alzheimer’s disease, the severity of symptoms is linked to a loss of synaptic density and the spread of pathologically hyperphosphorylated tau.
Janine Utz +9 more
doaj +1 more source

