Results 21 to 30 of about 47,565 (201)

Immunohistochemical expression of markers Ki-67, neun, synaptophysin, p53 and HER2 in medulloblastoma and its correlation with clinicopathological parameters Expressão imunoistoquímica dos marcadores Ki-67, neun, sinaptofisina, p53 e HER2 em meduloblastoma e sua correlação com os parâmetros clínico-patológicos

open access: yesArquivos de Neuro-Psiquiatria, 2008
Medulloblastoma (MB) is the most common malignant brain tumor in childhood. The alterations found include: presence of oncoproteins p53 and HER2, elevated mitotic index, and presence of neuronal differentiation. The aim of this study was to determine the
Rosalva Thereza Meurer   +6 more
doaj   +1 more source

Pure small cell neuroendocrine carcinoma of urinary bladder: A case report

open access: yesClinical Case Reports, 2022
Small cell neuroendocrine carcinoma of the bladder is rare. We report a case of small cell carcinoma of the bladder with extensive regional lymph node metastases who underwent radical cystoprostatectomy and subsequent adjuvant systemic chemotherapy and ...
Abbas Eshraghi   +5 more
doaj   +1 more source

Correlation with basic differentiation processes of neurons [PDF]

open access: yes, 1991
The development of the spinal cord involves the proliferation of neurons, their migration to well-defined areas, fiber outgrowth and synapse formation. The present study was designed to correlate the spatiotemporal pattern of expression of synaptophysin,
Lahr, G.   +3 more
core   +1 more source

Immunohistochemistry and Radiomic Features for Survival Prediction in Small Cell Lung Cancer

open access: yesFrontiers in Oncology, 2020
Background: The aim of the study was to evaluate the role of different immunohistochemical and radiomics features in patients with small cell lung cancer (SCLC).Methods: Consecutive patients with histologically proven SCLC with limited (n = 47, 48%) or ...
Eleni Gkika   +25 more
doaj   +1 more source

Ndufs4 ablation decreases synaptophysin expression in hippocampus [PDF]

open access: yesScientific Reports, 2021
AbstractAltered function of mitochondrial respiratory chain in brain cells is related to many neurodegenerative diseases. NADH Dehydrogenase (Ubiquinone) Fe-S protein 4 (Ndufs4) is one of the subunits of mitochondrial complex I and its mutation in human is associated with Leigh syndrome.
Subrata Kumar Shil   +9 more
openaire   +3 more sources

Hydrogen Inhalation Protects against Ototoxicity Induced by Intravenous Cisplatin in the Guinea Pig

open access: yesFrontiers in Cellular Neuroscience, 2017
Introduction: Permanent hearing loss and tinnitus as side-effects from treatment with the anticancer drug cisplatin is a clinical problem. Ototoxicity may be reduced by co-administration of an otoprotective agent, but the results in humans have so far ...
Anette E. Fransson   +5 more
doaj   +1 more source

Effects of Environmental Enrichment in Maternally Separated Rats: Age and Sex-Specific Outcomes

open access: yesFrontiers in Behavioral Neuroscience, 2019
Maternal separation (MS) early in life is related to an increase in anxiety and depressive-like behaviors and neurobiological alterations mostly related to alterations in hypothalamic pituitary adrenal (HPA) axis reactivity. Environmental enrichment (EE)
Raura Doreste-Mendez   +7 more
doaj   +1 more source

Visualization of Synchronous or Asynchronous Release of Single Synaptic Vesicle in Active-Zone-Like Membrane Formed on Neuroligin-Coated Glass Surface

open access: yesFrontiers in Cellular Neuroscience, 2018
Fast repetitive synaptic transmission depends on efficient exocytosis and retrieval of synaptic vesicles around a presynaptic active zone. However, the functional organization of an active zone and regulatory mechanisms of exocytosis, endocytosis and ...
Junichiro Funahashi   +2 more
doaj   +1 more source

Effect of Bone Marrow-Derived Mesenchymal Stem Cells on the Hippocampal CA1 Area of Aluminium Chloride-Induced Alzheimer's Disease in Adult Male Albino Rat: A Histological and Immunohistochemical Study [PDF]

open access: yesThe Egyptian Journal of Histology, 2022
Introduction: Alzheimer’s disease (AD) is the commonest cause of dementia among the elderly. Aluminium is a toxic metal that primarily affects the hippocampus.
Eman El-Beltagi   +4 more
doaj   +1 more source

Cerebrospinal Fluid of Patients With Alzheimer’s Disease Contains Increased Percentages of Synaptophysin-Bearing Microvesicles

open access: yesFrontiers in Aging Neuroscience, 2021
IntroductionIn Alzheimer’s disease, the severity of symptoms is linked to a loss of synaptic density and the spread of pathologically hyperphosphorylated tau.
Janine Utz   +9 more
doaj   +1 more source

Home - About - Disclaimer - Privacy