Results 11 to 20 of about 75,268 (264)

Neuroendocrine differentiation of prostate cancer [PDF]

Asian Journal of Andrology, 2013
Benign prostate and prostatic adenocarcinoma contain rare quiescent neuroendocrine cells while small cell neuroendocrine carcinoma (SCNC), a variant form of prostate cancer, contains highly proliferative neuroendocrine tumor cells. We provide evidence that IL-8-CXCR2-P53 pathway keeps the NE cells in a quiescent state normally. P53 mutation inactivates
Zhen, Li, Clark J, Chen, Jason K, Wang, Elaine, Hsia, Wei, Li, Jill, Squires, Yin, Sun, Jiaoti, Huang   +7 more
openaire   +2 more sources

Correlation of Neuroendocrine Differentiation with Neuroendocrine Cell Hyperplasia and Vascular Endothelial Growth Factor in Colorectal Adenocarcinoma

مجلة بغداد للعلوم, 2021
Neuroendocrine differentiation has been mentioned in many cancers of non-neuroendocrinal organs, involving the gastrointestinal tract. In contrast, the correlation of focally diffused neuroendocrine differentiation in colorectal adenocarcinoma with ...
Khesar Hussein Khalil, Bashar Al-Hassawi , Jasim Abdo   +2 more
doaj   +1 more source

Neuroendocrine differentiation in prostate neoplasms. [PDF]

Pathologie (Heidelb)
Abstract Neuroendocrine (NE) cells in the prostate are part of the diffuse NE system and are found in both the normal prostate and acinar adenocarcinomas, occasionally exhibiting Paneth cell-like morphology. NE cells produce peptide hormones and biogenic amines that influence the differentiation and growth of the ...
Grobholz R.
europepmc   +3 more sources

Neuroendocrine differentiation in prostatic malignancy [PDF]

Cancer, 1996
The prostatic neuroendocrine cell is a regulatory cell that produces serotonin and peptide hormones. This cell is part of a more widely dispersed diffuse neuroendocrine regulatory system known as the APUD system. Focal neuroendocrine differentiation is seen in virtually all prostate carcinomas to one degree or another.
P A, di Sant'Agnese, A T, Cockett
openaire   +2 more sources

Cytoprotective and Neurotrophic Effects of Octadecaneuropeptide (ODN) in in vitro and in vivo Models of Neurodegenerative Diseases

Frontiers in Endocrinology, 2020
Octadecaneuropeptide (ODN) and its precursor diazepam-binding inhibitor (DBI) are peptides belonging to the family of endozepines. Endozepines are exclusively produced by astroglial cells in the central nervous system of mammals, and their release is ...
Olfa Masmoudi-Kouki, Amira Namsi, Amira Namsi, Yosra Hamdi, Seyma Bahdoudi, Seyma Bahdoudi, Ikram Ghouili, Julien Chuquet, Jérôme Leprince, Jérôme Leprince, Benjamin Lefranc, Benjamin Lefranc, Taoufik Ghrairi, Marie-Christine Tonon, Gérard Lizard, David Vaudry, David Vaudry   +16 more
doaj   +1 more source

Rectal carcinoma with dual differentiation toward enteroblastic and neuroendocrine features arising in a patient with ulcerative colitis: a case report

World Journal of Surgical Oncology, 2022
Background Colorectal carcinoma with enteroblastic differentiation is a rare subtype of colorectal carcinomas expressing at least one characteristic immunohistochemical marker among α-fetoprotein, glypican-3, and spalt-like transcription factor 4. On the
Takako Kihara, Ryuichi Kuwahara, Kurando Kusunoki, Tomohiro Minagawa, Yuki Horio, Motoi Uchino, Hiroki Ikeuchi, Seiichi Hirota   +7 more
doaj   +1 more source

Characterization of the EM66 Biomarker in the Pituitary and Plasma of Healthy Subjects With Different Gonadotroph Status and Patients With Gonadotroph Tumor

Frontiers in Endocrinology, 2019
Granins and their derived-peptides are useful markers of secretion from normal and tumoral neuroendocrine cells. The need to identify new diagnostic markers for neuroendocrine tumors, including pituitary tumors prompted us to determine plasma levels of ...
Johann Guillemot, Marlène Guérin, Anne-Françoise Cailleux, Antoine-Guy Lopez, Jean-Marc Kuhn, Youssef Anouar, Laurent Yon   +6 more
doaj   +1 more source

The neuropeptide 26RFa in the human gut and pancreas: potential involvement in glucose homeostasis

Endocrine Connections, 2019
Objective: Recent studies performed in mice revealed that the neuropeptide 26RFa regulates glucose homeostasis by acting as an incretin and by increasing insulin sensitivity.
Gaëtan Prévost, Marie Picot, Marie-Anne Le Solliec, Arnaud Arabo, Hind Berrahmoune, Mouna El Mehdi, Saloua Cherifi, Alexandre Benani, Emmanuelle Nédélec, Françoise Gobet, Valéry Brunel, Jérôme Leprince, Hervé Lefebvre, Youssef Anouar, Nicolas Chartrel   +14 more
doaj   +1 more source

The Prognostic Significance of Neuroendocrine Differentiation in Colorectal Carcinomas: Our Experience [PDF]

Journal of Clinical and Diagnostic Research, 2015
Introduction: Neuroendocrine differentiation in colorectal carcinomas, detected using immunohistochemistry and ultrastructural techniques, has been studied as a prognostic marker for invention of targeted therapy. There are a few studies done on this
Pooja Kundapur Suresh, Kausalya Kumari Sahu, Radha Ramachandra Pai, Hanaganahalli Basaviah Sridevi, Kirthinath Ballal, Binit Khandelia, Jessica Minal, Rajendra Annappa   +7 more
doaj   +1 more source

Neuroendocrine differentiation of adrenocortical tumors [PDF]

Cancer, 1995
The syndrome of multiple endocrine neoplasia type 1 frequently involves the adrenal cortex. The relationship between the diffuse neuroendocrine system and the adrenal cortex is not clear however, particularly as the adrenal cortex is not considered to be an intrinsic part of the diffuse neuroendocrine system.The possible relationship between the ...
H R, Haak, G J, Fleuren
openaire   +2 more sources