Results 41 to 50 of about 104,178 (284)
BMC Cancer, 2020 Background Gastric neoplasms containing neuroendocrine carcinoma (NEC) components are rare malignancies with highly aggressive behavior and a poor prognosis and include pure NEC and mixed tumors containing NEC components.
Jiahui Chen +4 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
World Journal of Surgical Oncology, 2023 Background/aim This study investigated the clinicopathological characteristics and treatment of appendix neuroendocrine neoplasms in appendectomy specimens of our center.
He-wei Zhang +3 more
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Surgical Procedures for Neuroendocrine Neoplasms of the Appendix: A Consensus Guideline Review [PDF]
Journal of Biomedical & Clinical Research, 2018 According to the consensus and the recommendations of the European Neuroendocrine Tumor Society (ENETS), the frequency of appendicular neuroendocrine tumors (NETs) is 0.15-0.6/100 000 a year.
Paulina Vladova +2 more
doaj +3 more sources
Surgical Therapy of Pancreatic Neuroendocrine Neoplasms
, 2015 Pancreatic neuroendocrine tumors are relatively rare entities, which consist of single or multiple benign or malignant neoplasms. It will be shown that in 10-20 % of patients, they can be associated with inherited syndromes, such as multiple endocrine ...
Muffatti F. +9 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Surgery in Practice and Science, 2022 Pancreatic neuroendocrine neoplasms (pNENs) are a group of heterogeneous neoplasms originating from pancreatic neuroendocrine cells. In recent years, with the development of diagnostic technology, the incidence has increased in the past decades.
Bohui Yin +4 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Endocrine Connections, 2021 Calcitonin-secreting neuroendocrine neoplasms of the lung are rare, with few cases reported in the literature. Differentiating between medullary th yroid carcinoma and an ectopic source of calcitonin secretion can represent a complex diagnostic conundrum
David C Llewellyn +8 more
doaj +1 more source