Lurbinectedin in treating CNS metastases from small cell neuroendocrine prostate cancer—a case report [PDF]
Frontiers in OncologyBackgroundDe novo neuroendocrine prostate cancer is an aggressive, androgen receptor-independent subtype of prostate cancer with poor prognosis. Central nervous system (CNS) metastases from de novo neuroendocrine prostate tumors are rare, and evidence ...
Avani Gunuganti +4 more
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Multimodal management of primary mixed neuroendocrine prostate cancer with bone flare phenomenon: a rare case report and therapeutic insights [PDF]
BMC UrologyBackground Neuroendocrine prostate cancer (NEPC) is a rare and aggressive subtype of prostate cancer, accounting for approximately 0.5%–2% of cases. Mixed NEPC, composed of both adenocarcinoma and neuroendocrine components, represents a biologically ...
Lijing Xu, Jialin Wang
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De novo small cell neuroendocrine prostate cancer: An atypical case presentation [PDF]
Urology Case ReportsSmall cell neuroendocrine carcinoma comprises less than 1 % of all prostate cancers. We report a case of a 62-year-old male who presented acutely with severe lower urinary tract symptoms (LUTS), including nocturia, but with normal prostate-specific ...
Yalda Rahmani +9 more
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Primary large-cell neuroendocrine carcinoma of the prostate [PDF]
Archives of the Balkan Medical Union, 2022 Introduction. Depending on neuroendocrine differentiation, the prostate cancer is divided into two major groups: primary neuroendocrine prostate tumour (carcinoid, small-cell, and large-cell neuroendocrine carcinoma) or as a focal tumour in conventional ...
Spasimir T. SHOPOV
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Serotonin sets up neutrophil extracellular traps to promote neuroendocrine prostate cancer metastasis in the liver [PDF]
The Journal of Clinical InvestigationCastration-resistant prostate cancer frequently metastasizes to the liver, and prostate cancer liver metastases often present a neuroendocrine phenotype (i.e., neuroendocrine prostate cancer [NEPC]), but the underlying molecular underpinnings remain ...
Dean G. Tang
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Neuroendocrine cancer of the prostate. Two case reports
Journal of Men's Health, 2022 Background: Neuroendocrine cancer of the prostate can present in diverse clinical pictures, potentially hampering the diagnosis and probably leading to underdiagnosis.
Tamás Kullmann +3 more
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Endocrine and paracrine characteristics of neuroendocrine prostate cancer
Frontiers in Endocrinology, 2022 Prostate cancer is a common malignancy affecting men worldwide. While the vast majority of newly diagnosed prostate cancers are categorized as adenocarcinomas, a spectrum of uncommon tumor types occur including those with small cell and neuroendocrine ...
Tarana Arman +2 more
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IJU Case Reports, 2022 Introduction Treatment strategy for castration‐resistant prostate cancer with neuroendocrine differentiation after radiation therapy has not been established.
Takahiro Komori +8 more
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Mechanisms of castration resistant prostate cancer formation and progression through neuroendocrine differentiation [PDF]
Journal of Men's Health, 2021 Normal prostate tissues consist mainly of epithelial cells, including secretory epithelial cells, basal cells, and neuroendocrine cells, and of mesenchymal cells, including smooth muscle cells and fibroblasts.
Xueping Ma +2 more
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Regulation of Neuroendocrine-like Differentiation in Prostate Cancer by Non-Coding RNAs
Non-Coding RNA, 2021 Neuroendocrine prostate cancer (NEPC) represents a variant of prostate cancer that occurs in response to treatment resistance or, to a much lesser extent, de novo.
Eva Slabáková +3 more
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