Results 41 to 50 of about 20,018 (209)
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.ABSTRACT A comprehensive synthesis of the broad range of neurodevelopmental and psychiatric manifestations in NF1 is needed to identify knowledge gaps and future directions for NF1 research. In the following scoping review, we identify and summarize the scope of research that examines neurodevelopmental and psychiatric manifestations, both as ...
Meera Chopra +5 more
wiley +1 more source
Unusual Case of a Proptosed Eye: Isolated Right Maxillary Neurofibroma
Case Reports in Pathology, 2016 Neurofibroma is a slow growing benign tumour of the peripheral nerve sheath which is frequently associated with neurofibromatosis type 1 (Prakash et al., 2014).
Darren Yap +2 more
doaj +1 more source
Integrative genomic analyses of neurofibromatosis tumours identify SOX9 as a biomarker and survival gene [PDF]
, 2013 Understanding the biological pathways critical for common neurofibromatosis type 1 (NF1) peripheral nerve tumours is essential, as there is a lack of tumour biomarkers, prognostic factors and therapeutics.
Aronow, Bruce J +19 more
core +1 more source
Trametinib in Adults with Neurofibromatosis Type 1‐Related Symptomatic Plexiform Neurofibromas
Annals of Neurology, EarlyView.Objective Mitogen‐activated protein kinase kinase inhibitors have shown promising results in treatment of plexiform neurofibromas in neurofibromatosis type 1 patients, but data in adults are limited. The aim of this phase 2 study was to investigate the efficacy and safety of trametinib in adults with neurofibromatosis type 1.
D. Christine Noordhoek +7 more
wiley +1 more source
Giant elephantiasis neuromatosa in the setting of neurofibromatosis type 1: A case report [PDF]
, 2016 Elephantiasis neuromatosa (EN) can arise from a plexiform neurofibroma of the superficial and deep nerves developing from a hyperproliferation of the perineural connective tissue infiltrating adjacent fat and muscles.
Dealis, Cristina +9 more
core +1 more source
Developmental Dynamics, EarlyView.Abstract Neural crest cells are a transient cell population that emerges from the dorsal neural tube during neurulation and migrates extensively throughout the embryo. Among their diverse derivatives, glial cells (such as Schwann and satellite ganglionic cells) and melanocytes represent two major lineages. In vitro studies suggested they share a common
Chaya Kalcheim
wiley +1 more source
Dermatopathology, 2017 Hybrid benign peripheral nerve sheath tumors are rare tumors exhibiting areas of more than one neural neoplasm such as schwannoma/neurofibroma, neurofibroma/perineurioma, or schwannoma/perineurioma.
Shirien Shanouda, Gürkan Kaya
doaj +1 more source
Primary Bladder Neurofibroma: A Rare Case with Clinical Implications and Diagnostic Challenges [PDF]
Journal of Clinical and Diagnostic Research, 2015 Neurofibroma of the genito-urinary tract is rare. Urinary bladder is the commonest organ involved in cases of urinary tract involvement. Patients present early in life and there is male preponderance.
Srikanth Umakanthan +4 more
doaj +1 more source
A patient with neurofibroma (schwannoma) in peri-sacral: A case report [PDF]
, 2015 Schwannomas are benign tumors of the nerve sheath and are usually single encapsulated and slow growing in peripheral or sympathetic nervous system. In this report a 49 year-old man is presented with one year complain of abdominal pain and intermittent ...
Jouybari, L. +3 more
core
Arteriovenous malformation underlying a plexiform neurofibroma: An unusual presentation
Indian Dermatology Online Journal, 2017 Vascular abnormalities associated with neurofibromatosis type 1 are well described in the literature, however, arteriovenous malformation is a very rare finding in neurofibromatosis type 1.
Zaheer Abbas, Sepideh Khani, Javad Zare
doaj +1 more source