Results 121 to 130 of about 253,178 (331)
In Vivo Optical Imaging of Neurogenesis: Watching New Neurons in the Intact Brain [PDF]
, 2008 Sébastien Couillard‐Després +9 more
openalex +1 more source
Label‐Free Molecular Characterization of Protein Aggregates in Differentiated Astrocytes
Advanced Science, EarlyView.Mid‐infrared photothermal microscopy enables label‐free structural, molecular, and functional imaging of protein aggregates in astrocyte cells. The processes of astrocytes differentiated on a nanomaterial interface are characterized by α‐helical signatures combined with enhanced interfacial thermal resistance properties, while the cell soma of non ...
Panagis D. Samolis +9 more
wiley +1 more source
Neuroprotection, Recovery of Function and Endogenous Neurogenesis in Traumatic Spinal Cord Injury Following Transplantation of Activated Adipose Tissue [PDF]
, 2019 Stephana Carelli +7 more
openalex +1 more source
S3RL: Enhancing Spatial Single‐Cell Transcriptomics With Separable Representation Learning
Advanced Science, EarlyView.Separable Spatial Representation Learning (S3RL) is introduced to enhance the reconstruction of spatial transcriptomic landscapes by disentangling spatial structure and gene expression semantics. By integrating multimodal inputs with graph‐based representation learning and hyperspherical prototype modeling, S3RL enables high‐fidelity spatial domain ...
Laiyi Fu +6 more
wiley +1 more source
Alzheimer’s disease and Hippocampal Adult Neurogenesis; Exploring Shared Mechanisms
Frontiers in Neuroscience, 2016 New neurons incorporate into the granular cell layer of the dentate gyrus throughout life. Neurogenesis is modulated by behavior and plays a major role in hippocampal plasticity.
Orly eLazarov +2 more
doaj +1 more source
Advanced Science, EarlyView.In Parkinson's disease, SHMT1 downregulation disrupts its interaction with PEMT in astrocytes, reducing SAM levels. This leads to H3K4me1 hypomethylation and decreased Slc1a2/Glul expression, ultimately exacerbating neuroexcitotoxicity and dopaminergic neuron loss.
Yue‐Han Chen +17 more
wiley +1 more source
The CDK8 Complex and Proneural Proteins Together Drive Neurogenesis from a Mesodermal Lineage [PDF]
, 2017 Shuo Luo, H. Robert Horvitz
openalex +1 more source
RPS3‐Enriched Extracellular Vesicles Mediate Liver‐Spinal Cord Inter‐Organ Communication
Advanced Science, EarlyView.Spinal cord injury activates the liver to send extracellular vesicles loaded with RPS3 protein to the lesion site. These vesicles are taken up by neural stem cells and astrocytes, triggering NF‐κB signaling, impairing the regeneration of neurons and myelin, and promotes harmful inflammation, ultimately hindering recovery.
Peiwen Song +11 more
wiley +1 more source
LEARNING INDUCES THE EMERGENCE OF INDIVIDUALITY
IBRO Neuroscience Reports, 2023 Warsha Barde, Gerd Kempermann
doaj +1 more source
Neural Plasticity, 2014 Glucagon-like peptide-1 (GLP-1) regulates carbohydrate metabolism and promotes neurogenesis. We reported an inverse correlation between adult body mass and neurogenesis in nonhuman primates.
Jeremy D. Coplan +6 more
doaj +1 more source