Results 151 to 160 of about 218,517 (358)
An Adaptive Threshold in Mammalian Neocortical Evolution
, 2013 Expansion of the neocortex is a hallmark of human evolution. However, it remains an open question what adaptive mechanisms facilitated its expansion.
Huttner, Wieland B +4 more
core +3 more sources
Animal Models and Experimental Medicine, EarlyView.Quercetin regulates signaling pathways in neurodegenerative diseases, including NF‐κB, sirtuins, and PI3K/Akt. Studies show quercetin improves symptoms and pathology in neurodegenerative models. The study aims to incorporate laboratory research into practical medical treatment, focusing on quercetin's neuroprotective effects and optimal dosage ...
Md. Rezaul Islam +13 more
wiley +1 more source
Fabrication and Bioactivity of Peptide‐Conjugated Biomaterial Tissue Engineering Constructs
Macromolecular Rapid Communications, Volume 44, Issue 1, January 2023., 2023 Various fabrication techniques can be used to form tissue engineering constructs. These constructs can be conjugated with peptides in a straightforward fashion providing them with bioactivity. Peptides afford distinct advantages over other techniques for imparting bioactivity making peptide‐conjugated constructs excellent candidates to improve healing ...
Nicholas Nun, Abraham Joy
wiley +1 more source
Reproduction: A New Venue for Studying Function of Adult Neurogenesis?
Cell Transplantation, 2011 Adult neurogenesis has been a focus within the past few years because it is a newly recognized form of neuroplasticity that may play significant roles in behaviors and recovery process after disease.
Benson Wui-Man Lau +2 more
doaj +1 more source
Role of adult hippocampal neurogenesis in stress resilience
Neurobiology of Stress, 2015 There is a growing appreciation that adult hippocampal neurogenesis plays a role in emotional and cognitive processes related to psychiatric disorders. Although many studies have investigated the effects of stress on adult hippocampal neurogenesis, most ...
Brunno R. Levone +2 more
doaj +1 more source
Animal Models and Experimental Medicine, EarlyView.Abstract Background Intracerebral hemorrhage (ICH) remains a devastating neurological disorder with limited therapeutic options. Neural stem cell (NSC)‐based therapies have emerged as a potential regenerative approach, yet the molecular mechanisms regulating NSC behavior require further elucidation.
Wei Dai +7 more
wiley +1 more source
The involvement of Rcc2 in mammalian neurogenesis [PDF]
, 2016 Rcc2 is a Rac guanine nucleotide exchange factor recently identified as a principal signaling component of integrin adhesion complexes that also plays a central role in the completion of mitosis and cytokinesis.
Yanushefski, Lisa
core +1 more source
Animal Models and Experimental Medicine, EarlyView.KLF4 (Krüppel‐like factor 4) plays a protective role in blood–brain barrier (BBB). KLF4 plays an ambiguous role in the central nervous system. KLF4 in the BBB endothelial cells could be a potential target for Alzheimer's disease. Abstract Alzheimer's disease is the most prevalent chronic neurodegenerative disorder worldwide, with no sufficient cure ...
Ziying Wei +4 more
wiley +1 more source
Neurogenesis-Inspired Dictionary Learning: Online Model Adaption in a Changing World [PDF]
arXiv, 2017 In this paper, we focus on online representation learning in non-stationary environments which may require continuous adaptation of model architecture. We propose a novel online dictionary-learning (sparse-coding) framework which incorporates the addition and deletion of hidden units (dictionary elements), and is inspired by the adult neurogenesis ...
arxiv
Frontiers in Molecular NeuroscienceThe Ca2+-dependent activator protein for secretion (CAPS/CADPS) family protein facilitates catecholamine release through the dense-core vesicle exocytosis in model neuroendocrine cell lines.
Hirotoshi Iguchi +16 more
doaj +1 more source