Results 111 to 120 of about 16,632 (221)

The recommendations of a consensus panel for the screening, diagnosis, and treatment of neurogenic orthostatic hypotension and associated supine hypertension

Journal of Neurology, 2017
Neurogenic orthostatic hypotension (nOH) is common in patients with neurodegenerative disorders such as Parkinson’s disease, multiple system atrophy, pure autonomic failure, dementia with Lewy bodies, and peripheral neuropathies including amyloid or ...
C. Gibbons, P. Schmidt, I. Biaggioni, Camille G. Frazier-Mills, R. Freeman, S. Isaacson, B. Karabin, L. Kuritzky, M. Lew, P. Low, A. Mehdirad, S. Raj, S. Vernino, H. Kaufmann   +13 more
semanticscholar   +1 more source

Implications and opportunities regarding biological frameworks in overt and prodromal dementia with Lewy bodies

Alzheimer's &Dementia, Volume 21, Issue 7, July 2025.
Abstract Dementia with Lewy bodies (DLB), a progressive neurodegenerative disease with heterogeneous clinical presentations, greatly impacts patients, caregivers, and society. Despite its frequency, diagnosing and treating DLB remains challenging. Advances in in vivo biomarker assays reflecting underlying pathology are improving disease identification,
Jennifer G. Goldman, Bradley F. Boeve, Douglas Galasko, John‐Paul Taylor, James E. Galvin, James B. Leverenz, Frederic Blanc, Glenda Halliday, Kejal Kantarci, Afina W. Lemstra, Iracema Leroi, Simon J. G. Lewis, Irene Litvan, Helen Medsger, John O'Brien, Sonja W. Scholz, Dag Aarsland, Manabu Ikeda, Ian McKeith, Angela Taylor   +19 more
wiley   +1 more source

Frequency of orthostatic hypotension in the Pooled Resource Open-Access ALS Clinical Trials database

Frontiers in Neurology
PurposeTo explore the frequency of orthostatic hypotension (OH) in a large sample of amyotrophic lateral sclerosis patients (ALS).MethodsFrom the PRO-ACT database, data of 1,240 ALS patients were analyzed, focusing on blood pressure and heart rate before
C. Quarracino, F. Capani, F. Capani, M. Otero-Losada, G. E. Rodríguez, S. Pérez-Lloret, S. Pérez-Lloret   +6 more
doaj   +1 more source

Comparison of Dysautonomia Across Species: Current Knowledge and Future Research Opportunities

Journal of Veterinary Internal Medicine, Volume 39, Issue 4, July/August 2025.
ABSTRACT Primary dysautonomia is a complex and often fatal autonomic nervous system disease. This literature review consolidates information on dysautonomia across species. Electronic databases (PubMed, Google Scholar and the Equine Grass Sickness Fund website) were systematically searched for veterinary and human medical literature on the topic.
Callum N. Atkins, Caroline N. Hahn, Bruce C. McGorum   +2 more
wiley   +1 more source

Being Prodromal: Current Criteria in the Context of Isolated REM Sleep Behavior Disorder

Movement Disorders Clinical Practice, Volume 12, Issue 6, Page 828-834, June 2025.
ABSTRACT Background Isolated REM sleep behavior disorder (iRBD) indicates an early α‐synucleinopathy with approximately 90% of individuals pheno‐converting to Parkinson's disease (PD), dementia with Lewy bodies (DLB), or multiple system atrophy (MSA). Recently, prodromal disease definitions (pPD, pDLB, pMSA) have been introduced.
Anja Ophey, Sinah Röttgen, Julia Reichrath, Elke Kalbe, Gereon R. Fink, Michael Sommerauer   +5 more
wiley   +1 more source

Neurogenic orthostatic hypotension – management update and role of droxidopa

Therapeutics and Clinical Risk Management, 2015
Joy Vijayan,1 Vijay K Sharma1,21Department of Medicine, Division of Neurology, National University Health System, 2Yong Loo Lin School of Medicine, National University of Singapore, SingaporeAbstract: Orthostatic hypotension (OH) is defined as a ...
Vijayan J, Sharma VK
doaj  

Cardiac sympathetic innervation and vesicular storage in pure autonomic failure

Annals of Clinical and Translational Neurology, 2020
Objective Pure autonomic failure (PAF) is a rare disease characterized by neurogenic orthostatic hypotension (nOH), absence of signs of central neurodegeneration, and profound deficiency of the sympathetic neurotransmitter norepinephrine.
David S. Goldstein, Risa Isonaka, Courtney Holmes, Yu‐Shin Ding, Yehonatan Sharabi   +4 more
doaj   +1 more source

New insights into orthostatic hypotension in multiple system atrophy: a European multicentre cohort study [PDF]

, 2015
Objectives: Orthostatic hypotension (OH) is a key feature of multiple system atrophy (MSA), a fatal progressive neurodegenerative disorder associated with autonomic failure, parkinsonism and ataxia.
Calandra Buonara, G., Cochen De Cock, V., Colosimo, C., Cortelli, P., Debs, R., Duerr, S., Fanciulli, A., Foubert Samier, A., Gerdelat, Angela, Gurevich, T., Krismer, F., Meissner, Wassilios G., Pavy Le Traon, Anne, Piedvache, A., Poewe, W., Pérez Lloret, Santiago, Rascol, Olivier, Tison, Francois, Tranchant, C., Wenning, G.   +19 more
core   +1 more source

Should Neurogenic Supine Hypertension Be Treated? Insights from Hypertension-Mediated Organ Damage Studies—A Narrative Review

Biomedicines
Neurodegenerative synucleinopathies—including Parkinson’s disease, multiple system atrophy, pure autonomic failure, and dementia with Lewy bodies—often feature cardiovascular autonomic dysfunction.
Cristiano Fava, Federica Stocchetti, Sara Bonafini   +2 more
doaj   +1 more source

Effect of Acute Exposure to Hypergravity (Gx vs. Gz) on Dynamic Cerebral Autoregulation [PDF]

We examined the effects of 30 min of exposure to either +3G(sub x) or +3G(sub z) centrifugation on cerebrovascular responses to 800 head-up tilt (HUT) in 14 healthy individuals.
Bondar, R. L., Kassam, M. S., Picot, P. A., Rupert, A. H., Schlegel, T. T., Serrador, Jorge M., Stein, F., Wood, S. J.   +7 more
core   +1 more source