Psychometric validation of a patient-reported single-item assessment of ‘Good Day Bad Day’ in a neurogenic orthostatic hypotension population treated with droxidopa [PDF]
Journal of Market Access & Health Policy, 2022 Background Symptoms of neurogenic orthostatic hypotension (nOH), including lightheadedness/dizziness, presyncope, syncope, and falls, can lead to impaired functional ability and reduced quality of life.
Clément François +5 more
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Characterization of the changes in supine blood pressure with long‐term use of droxidopa in patients with neurogenic orthostatic hypotension [PDF]
Health Science Reports, 2021 Background and Aims Patients with neurogenic orthostatic hypotension (nOH) due to autonomic dysfunction may also experience supine hypertension (defined as supine systolic blood pressure [SBP] ≥140 mmHg).
L. Arthur Hewitt +5 more
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Primary neurogenic orthostatic hypotension [PDF]
Journal of Neurology, Neurosurgery & Psychiatry, 1970 Eight further cases of neurogenic orthostatic hypotension are described together with a necropsy study on one case. Three cases showed evidence of autonomic dysfunction in isolation, while in five cases this was accompanied by evidence of more diffuse central nervous system degeneration.
R C, Hughes, N E, Cartlidge, P, Millac
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Prospects for Droxidopa in Neurogenic Orthostatic Hypotension [PDF]
Hypertension, 2015 See related article, pp 101–107 Neurogenic orthostatic hypotension (nOH) is a debilitating disorder defined by a sustained decrease in systolic blood pressure of 20 mm Hg or in diastolic blood pressure of 10 mm Hg within 3 minutes of head-up tilt or standing.1 The disorder is associated with attenuated increases in plasma norepinephrine and peripheral
Amanda J, Ross, Julian M, Stewart
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A validated test for neurogenic orthostatic hypotension at the bedside. [PDF]
Ann Neurol, 2018 Norcliffe-Kaufmann L +2 more
europepmc +6 more sources
Droxidopa in neurogenic orthostatic hypotension [PDF]
Expert Review of Cardiovascular Therapy, 2015 Neurogenic orthostatic hypotension (nOH) is a fall in blood pressure (BP) on standing due to reduced norepinephrine release from sympathetic nerve terminals. nOH is a feature of several neurological disorders that affect the autonomic nervous system, most notably Parkinson disease (PD), multiple system atrophy (MSA), pure autonomic failure (PAF), and ...
Horacio, Kaufmann +2 more
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Cerebral perfusion in neurogenic orthostatic hypotension [PDF]
The Lancet Neurology, 2008 Contains fulltext : 69875.pdf (Author’s version postprint ) (Open Access)
Jurgen A.H.R. Claassen
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Neurogenic orthostatic hypotension: pathophysiology, evaluation, and management [PDF]
Journal of Neurology, 2012 Neurogenic orthostatic hypotension is a distinctive and treatable sign of cardiovascular autonomic dysfunction. It is caused by failure of noradrenergic neurotransmission that is associated with a range of primary or secondary autonomic disorders, including pure autonomic failure, Parkinson's disease with autonomic failure, multiple system atrophy as ...
Metzler, Manuela +5 more
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Clinical management of neurogenic orthostatic hypotension
Annals of Movement Disorders, 2019 Neurogenic orthostatic hypotension is a common disorder often seen in elderly patients affected with neurodegenerative disorders and peripheral neuropathies.
Malligurki Raghurama Rukmani +3 more
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Treatment of Orthostatic Hypotension Due to Autonomic Dysfunction (Neurogenic Orthostatic Hypotension) in a Patient with Cardiovascular Disease and Parkinson's Disease [PDF]
Cardiology and Therapy, 2019 Introduction The prevalence of neurogenic orthostatic hypotension (nOH) increases with age and is associated with autonomic failure in neurodegenerative diseases (e.g., Parkinson's disease).
Peter A. McCullough
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