Results 11 to 20 of about 4,120 (174)

Droxidopa in neurogenic orthostatic hypotension [PDF]

open access: yesExpert Review of Cardiovascular Therapy, 2015
Neurogenic orthostatic hypotension (nOH) is a fall in blood pressure (BP) on standing due to reduced norepinephrine release from sympathetic nerve terminals. nOH is a feature of several neurological disorders that affect the autonomic nervous system, most notably Parkinson disease (PD), multiple system atrophy (MSA), pure autonomic failure (PAF), and ...
Horacio Kaufmann   +2 more
openaire   +3 more sources

Neurogenic Orthostatic Hypotension [PDF]

open access: yesCirculation, 2009
Orthostatic hypotension (OH) is defined as a persistent, consistent, orthostatic fall in systolic blood pressure of ≥20 mm Hg or diastolic pressure of ≥10 mm Hg by 3 minutes of standing up.1 Acute, unexpected, episodic falls in blood pressure while standing, as in neurocardiogenic syncope, do not satisfy criteria for OH.
Yehonatan Sharabi, David S. Goldstein
openaire   +2 more sources

Prospects for Droxidopa in Neurogenic Orthostatic Hypotension [PDF]

open access: yesHypertension, 2015
See related article, pp 101–107 Neurogenic orthostatic hypotension (nOH) is a debilitating disorder defined by a sustained decrease in systolic blood pressure of 20 mm Hg or in diastolic blood pressure of 10 mm Hg within 3 minutes of head-up tilt or standing.1 The disorder is associated with attenuated increases in plasma norepinephrine and peripheral
Julian M. Stewart, Amanda J. Ross
openaire   +3 more sources

Management of neurogenic orthostatic hypotension: an update [PDF]

open access: yesThe Lancet Neurology, 2008
Orthostatic hypotension (OH) is common in elderly people and in patients with disorders such as diabetes and Parkinson's disease. Grading of the severity of OH and its effect on the patient's quality of life are important. The symptoms vary with orthostatic stress, and subtle symptoms such as tiredness and cognitive impairment should be recognised ...
Phillip A. Low, Wolfgang Singer
openaire   +3 more sources

Impact of the COVID-19 pandemic on clinical autonomic practice in Europe: a survey of the European Academy of Neurology and the European Federation of Autonomic Societies [PDF]

open access: yes, 2023
Background and purpose: The objective was to investigate the impact of the coronavirus disease 2019 (COVID-19) pandemic on European clinical autonomic practice.
Adamec I.   +66 more
core   +1 more source

Author response: Effects of orthostatic hypotension on cognition in Parkinson disease [PDF]

open access: yes, 2017
OBJECTIVE: To investigate the relation between orthostatic hypotension (OH) and posture-mediated cognitive impairment in persons with Parkinson's disease (PD) without dementia.
Canova, Alexander O.   +5 more
core   +1 more source

Neurogenic orthostatic hypotension: pathophysiology, evaluation, and management [PDF]

open access: yesJournal of Neurology, 2012
Neurogenic orthostatic hypotension is a distinctive and treatable sign of cardiovascular autonomic dysfunction. It is caused by failure of noradrenergic neurotransmission that is associated with a range of primary or secondary autonomic disorders, including pure autonomic failure, Parkinson's disease with autonomic failure, multiple system atrophy as ...
David Robertson   +5 more
openaire   +3 more sources

Squatting test: A posture to study and counteract cardiovascular abnormalities associated with autonomic dysfunction. [PDF]

open access: yes, 2011
The squatting test is an active posture manoeuvre that imposes one of the most potent orthostatic stresses. In normal subjects, the changes in blood pressure and heart rate are transient because of appropriate baroreflex homeostasis and do not provoke ...
PHILIPS, Jean-Christophe, SCHEEN, André
core   +1 more source

Electrodiagnostic assessment of the autonomic nervous system: A consensus statement endorsed by the American Autonomic Society, American Academy of Neurology, and the International Federation of Clinical Neurophysiology [PDF]

open access: yes, 2021
Evaluation of disorders of the autonomic nervous system is both an art and a science, calling upon the physician's most astute clinical skills as well as knowledge of autonomic neurology and physiology.
Ah Kim H.   +18 more
core   +1 more source

Autonomic symptoms in hypertensive patients with post-acute minor ischemic stroke [PDF]

open access: yes, 2015
Background Most studies regarding autonomic dysfunction in ischemic stroke are limited to heart rate and blood pressure changes during the acute phase. However, there are few data on quantitative assessment of autonomic symptoms.
Adams   +34 more
core   +1 more source

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