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Stroke, ischemic or hemorrhagic, triggers a complex and coordinated glial response, which, to a large extent, defines the progression and outcome of this focal damage of the nervous tissue. Massive cell death in the infarction core results in a release of damage-associated molecular patterns, which, together with blood-borne factors entering the brain ...
Verkhratsky, Alexei +1 more
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Verkhratsky, Alexei +1 more
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Neuroglia-living nerve glue,Neuroglia, der lebende Nervenkitt
Fortschritte der Neurologie Psychiatrie, 2011The brain is composed of two major cell types - neurons and glial cells. While neurons have been extensively studied, research on glia cells has picked up only in the last decades. There are three types of glia cells in the central nervous system: astrocytes, oligodendrocytes and microglia cells.
Kettenmann, H., Verkhratsky, A.
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General pathophysiology of neuroglia
Neuroglia in the CNS, represented by astroglia, oligodendroglia, and microglia, are responsible for the homeostatic support and protection of the nervous tissue. Neuroglia are intimately involved in the pathogenesis of all neurologic diseases, and neuroglial changes to a large extent define the progression of these diseases and their neurologic outcome.Verkhratsky, A. +4 more
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Neuroglia in anxiety disorders
Anxiety disorders are some of the most prevalent in the world and are extraordinarily debilitating to many individuals, costing millions in disability. One of the most disabling is posttraumatic stress disorder (Snijders et al., 2020). Understanding the pathophysiology of these illnesses further and the cell types involved will allow better targeting ...Robin E, Bonomi +2 more
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Neuroglia in autoimmune encephalitis
Neuroglial cells play a crucial role in central nervous system (CNS) health and disease. Antibody-associated autoimmune encephalitis (AE) represents a group of inflammatory brain diseases with antibodies (Abs) against neuronal cell surface (e.g., anti-N-methyl-d-aspartate receptor (NMDAR), anti-leucine-rich glioma-inactivated 1 (LGI1), γ-aminobutyric ...Fatme Seval, Ismail +3 more
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