Results 71 to 80 of about 17,069 (317)

Metabotropic Glutamate Receptor 5 Antagonism Reduces Pathology and Differentially Improves Symptoms in Male and Female Heterozygous zQ175 Huntington’s Mice

Frontiers in Molecular Neuroscience, 2022
Huntington’s disease (HD) is an inherited autosomal dominant neurodegenerative disorder that leads to progressive motor and cognitive impairment. There are currently no available disease modifying treatments for HD patients. We have previously shown that
Si Han Li, Si Han Li, Tash-Lynn L. Colson, Tash-Lynn L. Colson, Khaled S. Abd-Elrahman, Khaled S. Abd-Elrahman, Khaled S. Abd-Elrahman, Stephen S. G. Ferguson, Stephen S. G. Ferguson   +8 more
doaj   +1 more source

Assessment of concurrent neoplasms and a paraneoplastic association in MOGAD

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Cases of myelin oligodendrocyte glycoprotein (MOG) antibody‐associated disease (MOGAD) co‐occurring with neoplasms have been reported. In this international, retrospective cohort study in South Korea and the USA, 16 of 445 (3.6%) patients with MOGAD had concurrent neoplasm within 2 years of MOGAD onset, resulting in a standardized incidence ...
Young Nam Kwon, Nanthaya Tisavipat, Yong Guo, Stephanie B. Syc‐Mazurek, Ji Yeon Han, Jun‐Soon Kim, Kyomin Choi, Seong‐il Oh, Seok‐Jin Choi, Eunhee Sohn, Jeeyoung Oh, Seung Woo Kim, Ha Young Shin, Byung Chan Lim, Byoung Joon Kim, Kyung Seok Park, Jung‐Joon Sung, Se Hoon Kim, Sung‐Hye Park, Anastasia Zekeridou, Claudia F. Lucchinetti, Sean J. Pittock, John J. Chen, Eoin P. Flanagan, Sung‐Min Kim   +24 more
wiley   +1 more source

Sexual Dimorphism and Hypothalamic Astrocytes: Focus on Glioprotection

Neuroglia
Sexual dimorphism refers to biological differences between males and females in the same species, including morphological, physiological, and behavioral characteristics.
Natalie K. Thomaz, Larissa Daniele Bobermin, André Quincozes-Santos   +2 more
doaj   +1 more source

Sleep Disturbance in Bipolar Disorder: Neuroglia and Circadian Rhythms

Frontiers in Psychiatry, 2019
The worldwide prevalence of sleep disorders is approximately 50%, with an even higher occurrence in a psychiatric population. Bipolar disorder (BD) is a severe mental illness characterized by shifts in mood and activity.
L. Steardo, R. de Filippis, E. Carbone, C. Segura-García, A. Verkhratsky, P. De Fazio   +5 more
semanticscholar   +1 more source

CSF cytokine, chemokine and injury biomarker profile of glial fibrillary acidic protein (GFAP) autoimmunity

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Defining the CSF cytokine/chemokine and injury biomarker signature of glial fibrillary acidic protein (GFAP) autoimmunity can inform immunopathogenesis. CSF GFAP‐IgG‐positive samples (N = 98) were tested for 17 cytokines/chemokines, neurofilament light chain (NfL), and GFAP (ELLA, Bio‐Techne).
Yahel Segal, Georgios Mangioris, Vanda Lennon, Binxia Yang, Divyanshu Dubey, Eoin P. Flanagan, Andrew McKeon, John R. Mills, Michel Toledano, Ivana Vodopivec, Sean J. Pittock, Anastasia Zekeridou   +11 more
wiley   +1 more source

Impacts of Electroconvulsive Therapy on the Neurometabolic Activity in a Mice Model of Depression: An Ex Vivo ¹H-[¹³C]-NMR Spectroscopy Study

Neuroglia
Electroconvulsive therapy (ECT) is an effective treatment for severe and drug-resistant depression, yet its mode of action remains poorly understood.
Ajay Sarawagi, Pratishtha Wadnerkar, Vrundika Keluskar, Narra Sai Ram, Jerald Mahesh Kumar, Anant Bahadur Patel   +5 more
doaj   +1 more source

136. On the Structure of the Neuroglia [PDF]

The Journal of Nervous and Mental Disease, 1898
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openaire   +2 more sources

An MRI assessment of mechanisms underlying lesion growth and shrinkage in multiple sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
By applying the tensor model, we analysed lesion orientation and the directionality of lesion expansion/contraction in multiple sclerosis. Each lesion is summarized as an ellipsoid, and the tensor model is applied to calculate lesion anisotropy. From the top to the bottom white matter atlas, surface‐in gradient segmentation and venous atlas used in the
Ermelinda De Meo, Ferran Prados Carrasco, J. William L. Brown, Alasdair J. Coles, Nick G. Cunniffe, Amy E. Jolly, Baris Kanber, Rebecca Samson, Frederik Barkhof, Declan Chard   +9 more
wiley   +1 more source

Left-Parietal Angiocentric Glioma: Our Experience and a Review of the Literature

Neuroglia
Background: Angiocentric glioma (AG) is a rare, benign, and slow-growing tumor. First described in 2005, it is now gaining attention with respect to the possibility of being diagnosed.
Antonello Curcio, Shervin Espahbodinea, Eva Azzurra Li Trenta, Rosamaria Ferrarotto, Aristide Nanni, Noemi Arabia, Giorgio Ciccolo, Giovanni Raffa, Francesca Granata, Antonino Germanò   +9 more
doaj   +1 more source

UDP‐glucose dehydrogenase variants cause dystroglycanopathy

Annals of Clinical and Translational Neurology, EarlyView.
Abstract UDP‐glucose dehydrogenase (UGDH) variants have been associated with hypotonia, developmental delay, and epilepsy. We report the first pathologic evidence of dystroglycanopathy in siblings with UGDH variants. Both presented around 6 months with developmental delay and elevated creatinine kinase.
Anna M. Reelfs, Carrie M. Stephan, Theresa M. Czech, Mary O. Cox, Soumya Joseph, Benjamin W. Darbro, Steven A. Moore, Kevin P. Campbell, Katherine D. Mathews   +8 more
wiley   +1 more source