Results 81 to 90 of about 22,201 (325)

LIN28B Promotes Cancer Cell Dissemination and Angiogenesis

open access: yesAdvanced Biology, EarlyView.
Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo   +8 more
wiley   +1 more source

Current Understanding Regarding the Glioma Microenvironment and Impact of the Immune System

open access: yesNeuroglia
High-grade gliomas are aggressive, primary, central nervous system tumors with low survival rates due to recurrence and resistance to current therapy models.
Enes Demir   +4 more
doaj   +1 more source

Advanced Micro‐OLED Integration on Thin and Flexible Polymer Neural Probes for Targeted Optogenetic Stimulation

open access: yesAdvanced Functional Materials, EarlyView.
This paper introduces a flexible neural probe with integrated micro‐OLEDs on a flexible substrate for the first time, featuring 8 micro‐OLEDs and recording electrodes for optogenetics. It uses advanced encapsulation and an IAI anode for durability, emitting 470 nm light for ChR2 activation, enabling high‐resolution, minimally invasive stimulation ...
Somin Lee   +8 more
wiley   +1 more source

Central and Peripheral Immunity Responses in Parkinson’s Disease: An Overview and Update

open access: yesNeuroglia
Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by motor and non-motor symptoms, with increasing evidence supporting the role of immune dysregulation in its pathophysiology.
Ghaidaa Ebrahim   +3 more
doaj   +1 more source

VEGF(164)-mediated inflammation is required for pathological, but not physiological, ischemia-induced retinal neovascularization [PDF]

open access: yes, 2003
Hypoxia-induced VEGF governs both physiological retinal vascular development and pathological retinal neovascularization. In the current paper, the mechanisms of physiological and pathological neovascularization are compared and contrasted.
Adamis, AP   +14 more
core   +1 more source

136. On the Structure of the Neuroglia [PDF]

open access: yesThe Journal of Nervous and Mental Disease, 1898
n ...
openaire   +2 more sources

Optimizing Angiopep‐2 Density on Polymeric Nanoparticles for Enhanced Blood–Brain Barrier Penetration and Glioblastoma Targeting: Insights From In Vitro and In Vivo Experiments

open access: yesAdvanced Functional Materials, EarlyView.
The Angiopep‐2 peptide density on polymeric nanoparticles significantly impacts blood–brain barrier (BBB) penetration. This study explores this nuanced relationship using various in vitro models and in vivo assays, revealing that dynamic models better predict BBB penetration.
Weisen Zhang   +9 more
wiley   +1 more source

Strategies to Design and Optimize Artificial Antigen‐Presenting Cells for T Cell Expansion in Cancer Immunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley   +1 more source

A new theory of depression based on the serotonin/kynurenine relationship and the hypothalamicpituitary- adrenal axis

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2018
The serotonergic and immunological hypothesis of depression proposes that certain types of excessive stress distort the relationship between the activities of the innate immune and central nervous systems, so that the stress caused by an infection, or ...
Leslie Alejandra Ramírez   +5 more
doaj   +1 more source

Nerve Tissue [PDF]

open access: yes, 2009
Histology blog entry for January 6, 2009 about nerve ...
Krause, William J., II, 1942-
core  

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