Results 61 to 70 of about 3,232,639 (308)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Ferroptosis in Neurological Diseases

Frontiers in Cellular Neuroscience, 2020
Ferroptosis is mechanism for non-apoptotic, iron-dependent, oxidative cell death that is characterized by glutathione consumption and lipid peroxides accumulation.
Jia-Xin Ren, Jia-Xin Ren, Xin Sun, Xiu-Li Yan, Zhen-Ni Guo, Yi Yang   +5 more
doaj   +1 more source

Neurological Diseases and Pregnancy

, 2018
This book is intended for practitioners in the field of neurology, maternal fetal medicine, and obstetrics and gynecology. It is comprehensive in that it covers most neurological diseases, issues related to delivery and postpartum, use of neurological ...

core   +1 more source

cell therapy in neurological diseases

, 2023
Genetically modified immune cells, especially CAR-T cells, have captured the attention of scientists over the past 10 years. In the fight against cancer, these cells have a special place.
Siamak Sandoghchian Shotorbani, Kookli, K., Narges Soltani, Mahdi Zarei, Shahabifard, H., Hesam Shahabifard, Afyouni, N. E., Keihan Kookli, Ali Adili, Nazgol Esmalian Afyouni, Sairan Maghsoodi, Javad Mahmoudi, Adili, A., Shotorbani, S. S., Shomali, N., Maghsoodi, S., Mahmoudi, J., Zarei, M., Navid Shomali, Soltani, N.   +19 more
core   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Carotid endarterectomy and blood-brain barrier permeability in subjects with bilateral carotid artery stenosis

Chinese Neurosurgical Journal
Background The increased permeability of the blood–brain barrier (BBB) is related to the occurrence and development of diseases such as acute ischemic stroke, chronic ischemia, or small vessel disease.
Changyu Lu, Chenyu Zhu, Wenjie Li, Huan Zhu, Qihang Zhang, Tong Liu, Tongyu Yang, Yan Zhang   +7 more
doaj   +1 more source

Dual antiplatelet therapy with ticagrelor vs clopidogrel in patients with TIA or minor stroke with or without symptomatic carotid artery stenosis: a post hoc analysis of the CHANCE-2 trial

Stroke and Vascular Neurology
Background and purpose Symptomatic internal carotid artery stenosis (sCAS) is an essential cause of transient ischaemic attack (TIA) or minor stroke.
Yongjun Wang, Yilong Wang, Xingquan Zhao, Jing Jing, Hao Li, Xia Meng, Anxin Wang, Yong Jiang, Jinxi Lin, Qin Xu, Xuewei Xie, Pan Chen   +11 more
doaj   +1 more source

Autoantibodies in neurological disease [PDF]

Nature Reviews Immunology, 2021
The realization that autoantibodies can contribute to dysfunction of the brain has brought about a paradigm shift in neurological diseases over the past decade, offering up important novel diagnostic and therapeutic opportunities. Detection of specific autoantibodies to neuronal or glial targets has resulted in a better understanding of central nervous
openaire   +3 more sources

MicroRNA in glutamate receptor-dependent neurological diseases

, 2017
Glutamate-mediated excitotoxicity is the major neuropathological process contributing to numerous neurological diseases. Recently, emerging evidence indicates that microRNAs (miRNAs) play essential roles in the pathophysiology of a wide range of ...
Xiaoyan Long, Walid A. Alsharafi, Bo Xiao, Zhaohui Luo, Yuanyuan Xie   +4 more
core   +1 more source

Editorial: Novel therapeutic target and drug discovery for neurological diseases

, 2022
The Research Topic “Novel Therapeutic Target and Drug Discovery for Neurological Diseases” consists of 20 articles, including 12 original research papers, seven reviews, and one systematic review, with contributions from more than 140 authors.
Liu, Rui, Zhuorong Li (2731378), Liu, Qingshan, Riu Liu (14114301), Kaiyue Zhao (11795684), Cheng, Yong, Qingshan Liu (1286793), Barreto, George E., Yong Chen (11068833), GEORGE BARRETO (12351586), Zhao, Kaiyue, Li, Zhuorong   +11 more
core   +1 more source