Results 71 to 80 of about 3,232,639 (308)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Three Cases of Brain Tumor in Pregnancy

National Board of Examinations Journal of Medical Sciences
Background: Brain tumours in pregnancy are a pathology that carries risk to both maternal and fetal health. It is considered a case of interest in the point of surgical management.
Abhijit Patra, Laxminarayan Tripathy, Harsh Jain, Sunandan Basu, Mohammad Sarwar   +4 more
doaj   +1 more source

Neurologic Disease in Women. [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 1999
Neurologic Disease in Women. Edited by Peter Kaplan. (Pp 480 $150). Published by Demos, New York 1998. ISBN 1-888799-153. This is the second time that I have been asked to review a book on this topic. The first time I approached the task with some scepticism—were neurological diseases in women really so different from those in men that they warranted ...
openaire   +2 more sources

Stage progression and neurological symptoms in Trypanosoma brucei rhodesiense sleeping sickness: role of the CNS inflammatory response [PDF]

, 2012
Background: Human African trypanosomiasis progresses from an early (hemolymphatic) stage, through CNS invasion to the late (meningoencephalitic) stage.
MacLean, L., Peter G. E. Kennedy (126080), MacLean Lorna, Sternberg, J.M., Sternberg, Jeremy M, Peter G E Kennedy, Hansotto Reiber (126078), Sternberg Jeremy M., Reiber, H., Kennedy Peter G. E., Jeremy M Sternberg, Kennedy, Peter G E, Lorna MacLean, MacLean, Lorna, Lorna MacLean (126077), Jeremy M. Sternberg (126082), Reiber Hansotto, Kennedy, P.G.E., Reiber, Hansotto, Hansotto Reiber   +19 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Ruptured Suprasellar Dermoid Cyst presenting with Chemical Meningitis and Blindness

National Board of Examinations Journal of Medical Sciences
Background: Intracranial dermoid cysts (ICDC) are rare benign lesions. They typically originate from the ectoderm and contain dermal elements like hair follicles, sweat glands, sebaceous glands, and sometimes teeth.
Lakshya Varshney, Laxminarayan Tripathy, Harsh Jain, Sunandan Basu, Mohammad Sarwar   +4 more
doaj   +1 more source

ChatGPT's potential role in non-English-speaking outpatient clinic settings

Digital Health, 2023
Researchers recently utilized ChatGPT as a tool for composing clinic letters, highlighting its ability to generate accurate and empathetic communications.
Zhoule Zhu, Yuqi Ying, Junming Zhu, Hemmings Wu   +3 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Pallidal beta power is associated with depression in Parkinson’s disease

npj Parkinson's Disease
Depression is increasingly recognized as a prevalent source of disability in individuals with Parkinson’s disease (PD), but its pathophysiology is not well understood.
Kara A. Johnson, Patricia B. Coutinho, Lauren E. Kenney, Joshua K. Wong, Justin D. Hilliard, Kelly D. Foote, Dawn Bowers, Gregory M. Pontone, Coralie de Hemptinne   +8 more
doaj   +1 more source

Renal Dysfunction and In‐Hospital Outcomes in Patients With Acute Ischemic Stroke After Intravenous Thrombolytic Therapy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background The impact of estimated glomerular filtration rate (eGFR) on clinical short‐term outcomes after stroke thrombolysis with tissue plasminogen activator remains controversial.
Zhen‐Zhen Rao, Hong‐Qiu Gu, Xian‐Wei Wang, Xue‐Wei Xie, Xin Yang, Chun‐Juan Wang, Xingquan Zhao, Ying Xian, Yi‐Long Wang, Zi‐Xiao Li, Rui‐Ping Xiao, Yong‐Jun Wang   +11 more
doaj   +1 more source