Results 91 to 100 of about 3,232,639 (308)

Neurological Diseases: Implications in Medical and Dental Practices

, 2019
Neurological and neurodegenerative diseases have a significant impact on a patient's functionality, independence, and overall quality of life. Multidisciplinary clinical care, coordination, and treatment modifications are key to increasing survival rates
Ariana, Armin
core  

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

STN Versus GPi Deep Brain Stimulation for Action and Rest Tremor in Parkinson’s Disease

Frontiers in Human Neuroscience, 2020
ObjectiveTo investigate the effects of subthalamic nucleus (STN) and globus pallidus internus (GPi), deep brain stimulation (DBS) on individual action tremor/postural tremor (AT) and rest tremor (RT) in Parkinson’s disease (PD).
Joshua K. Wong, Vyas T. Viswanathan, Kamilia S. Nozile-Firth, Robert S. Eisinger, Emma L. Leone, Anuj M. Desai, Kelly D. Foote, Adolfo Ramirez-Zamora, Michael S. Okun, Aparna Wagle Shukla   +9 more
doaj   +1 more source

Idebenone: Clinical Potential Beyond Neurological Diseases [PDF]

Bin Yi,1– 4,* Jun Zeng,1– 4,* Jiashuo Li,1– 4,* Kunfeng Liu,1– 4 Xiaocheng Zhu,4,5 Xiang Chen,4,5 Yang Gao1– 4 1Department of Thoracic Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, People’s Republic of ...
Li J, Liu K, Yi B, Zeng J, Gao Y, Zhu X, Chen X   +6 more
core  

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Neurological Presentations of Endemic Tropical Diseases in Central Europe

Climate change increases the risk of tropical diseases—previously rare in Central Europe—emerging as local or zoonotic infections, not just imported cases.
Katarzyna Sikorska, G\uf3jska-Grymaj\u142o, Anna, Beata Biernat, Biernat, Beata, Sikorska, Katarzyna, Anna Gójska-Grymajło   +5 more
core   +1 more source

Neurological symptoms in infectious diseases [PDF]

, 2019
Poleszak Julita, Szabat Przemysław, Szabat Marta, Wójcik Magdalena, Boreński Grzegorz, Milanowska Joanna. Neurological symptoms in infectious diseases. Journal of Education, Health and Sport. 2019;9(9):930-945. eISNN 2391-8306.
Wójcik, Magdalena, Szabat, Przemysław, Poleszak, Julita, Szabat, Marta, Boreński, Grzegorz, Milanowska, Joanna   +5 more
core   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Changes in Length of Stay for Neurological Geriatric Diseases in Korea between 2003 and 2007

, 2011
Background and Purpose The elderly population and the prevalence of stroke, dementia, and Parkinson's disease are increasing rapidly in Korea. The aim of this study was to establish the length of stay (LOS) for neurological geriatric diseases, and ...
Im-Seok Koh, Bae, Hee-Joon, Koh, Im-Seok, Chang, Soung Hoon, Kim, Hyeong Su, Lee, Kun Sei, Hee-Joon Bae, Do-Hui Im, Soung Hoon Chang, Jae-Hyeok Heo, Hyeong Su Kim, Kun Sei Lee, Heo, Jae-Hyeok, Im, Do-Hui   +13 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source