Results 71 to 80 of about 381,065 (262)

Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran, Malo Gaubert, Alice Dufey, Elise Bannier, Audrey Rico, Jean‐Christophe Ferré, Raphaël Chouteau, Laure Michel, Emmanuelle Le Page, Virginie Callot, Bertrand Audoin, Sarah Demortière, Benoît Combès, Anne Kerbrat   +13 more
wiley   +1 more source

Jules Joseph Dejerine: an outstanding neurologist and Charcot's enemy

Arquivos de Neuro-Psiquiatria
Jules Joseph Dejerine (1849-1917) became renowned for his many contributions to neurology, including his anatomical and anatomo-functional studies, particularly those in the field of language and the peripheral nervous system. A disciple of Vulpian and a
Gustavo Koíti Kondo, Carla Caroline Schramm, Max Rainer Rosado Novaes, Hélio Afonso Ghizoni Teive   +3 more
doaj   +1 more source

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru, Akansha Chandrasekar, Kyla Blasingame, Jonathan Rosen, Jesse M. Levine, Karla Salazar, Madhuri Chilakapati, Rod Foroozan, Victoria Hardwick, Jonathan M. Yarimi, Nikita Shukla, Timothy E. Lotze, Kristen S. Fisher, Alexander J. Sandweiss   +13 more
wiley   +1 more source

The Role and Mechanism of Metformin in the Treatment of Nervous System Diseases

Biomolecules
Nervous system diseases represent a significant global burden, affecting approximately 16% of the world’s population and leading to disability and mortality.
Hui Li, Ruhui Liu, Junyan Liu, Yi Qu
doaj   +1 more source

Impact of Plasma p‐tau181 on Cognition, Motor Phenotypes, and Disease Course in ALS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Phosphorylated tau181 (p‐tau181), an Alzheimer's disease biomarker, was recently evaluated in amyotrophic lateral sclerosis (ALS). We investigated plasma p‐tau181 in 202 ALS/ALS‐FTD patients and 94 healthy controls, assessing cognitive performance, motor function, and longitudinal dynamics.
Elisabeth Kasper, Annaliis Lehto, Nina Nordmann, Oliver Peters, Julian Hellmann, Josef Priller, Eike Jakob Spruth, Gabor C. Petzold, Ina Vogt, Patrick Weydt, Sarah Bernsen, Elisabeth Dinter, Björn Falkenburger, René Günther, Emrah Düzel, Wenzel Glanz, Matthis Synofzik, Lukas Beichert, Annika Spottke, Michael Wagner, Frederic Brosseron, Matthias C. Schmid, Anja Schneider, Stefan Teipel, Johannes Prudlo, Andreas Hermann   +25 more
wiley   +1 more source

Optimizing filter trap assay for the detection of aggregated alpha-synuclein in brain samples

Free Neuropathology, 2020
Thibauld Oullier, Alice Prigent, Guillaume Chapelet, Michel Neunlist, Franck Letournel, Pascal Derkinderen   +5 more
doaj   +1 more source

Triclosan exposure potentiates ischemic stroke risk: Multi-omics integration and molecular docking unveil neurotoxic mechanisms

Ecotoxicology and Environmental Safety
This study applied network toxicology and multimodal biological approaches integrated with machine learning to systematically identify four TCS-IS-related genes, providing a comprehensive understanding of the pathophysiological relationship between ...
Fangyuan Cheng, Han Gao, Bo Yan, Fanglian Chen, Ping Lei   +4 more
doaj   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Charcot and vascular Parkinsonism

Arquivos de Neuro-Psiquiatria
Jean-Martin Charcot (1825-1893), recognized as the founder of Neurology and the first formal teacher of nervous system diseases, died on August 16, 1893, from acute pulmonary edema secondary to myocardial infarction. In his last years, there were several
Hélio A. G. Teive, Francisco M. B. Germiniani, Renato P. Munhoz   +2 more
doaj   +1 more source

[Neurology-psychiatry interface in central nervous system diseases].

Gaceta medica de Mexico, 2010
Brain pathologies are frequent sources of mental and behavioral disorders. In order to analyze the boundary between neurology and psychiatry, we analyzed all neuropsychiatric consultations seen at the inpatient Neurology, Neurosurgery, Critical Medicine and Neurological Emergencies clinics of the National Institute of Neurology and Neurosurgery of ...
Jesús, Ramírez-Bermúdez, Luis Carlos, Aguilar-Venegas, Cristian, Calero-Moscoso, Marisol, Ramírez-Abascal, Francisco, Nente-Chávez, Samantha, Flores-Reynoso, Fabián, Dolores-Velasco, Rogelio, Ramos-Tisnado   +7 more
openaire   +1 more source